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Literature for subfamily C1A

Summary Distribution Literature

(Topics flags: S Structure, P Specificity, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Alzoubi,L., Hamzat,Y., Alqudah,A. and Aljabali,A.A.A.<br>The Cathepsin Family in Disease: From Molecular Mechanisms to Therapeutic Applications<br>Curr Neuropharmacol (2025) PubMed  Europe PubMed DOI
  2. Bai,Y., Wang,H., Wu,M. and Cheng,Z.M.<br>Identification and expression analysis of papain-like cysteine proteases gene family and response to B. cinerea stress in F. vesca<br>BMC Plant Biol (2025) 25, 1294-1294. PubMed  Europe PubMed DOI  PMC  EPMC
  3. Chakraborty,R., Kannan,S.P., Afrose,N. and Narayanasamy,D.<br>Tumor microenvironment expressed enzymes (Matrix metalloproteinases, cathepsins, urokinase-type plasminogen activator) triggered polymersomes for liquid biopsy and cancer diagnostics: A review<br>Int J Biol Macromol (2025) 321, 146375-146375. PubMed  Europe PubMed DOI
  4. Fan,K., Li,X. and Wang,Z.<br>Exploring the Role of Exercise and the Lysosomal Cathepsin Family in the Regulation of Vascular-Musculoskeletal Degenerative Diseases<br>FASEB J (2025) 39, e71104-e71104. PubMed  Europe PubMed DOI
  5. Solomonov,I., Kollet,O. and Sagi,I.<br>Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior<br>FEBS J (2025) PubMed  Europe PubMed DOI
  6. Zhu,J., Gutkin,S., Chen,S., Su,S.P., Phan,H., Shabat,D. and Bogyo,M.<br>Chemiluminescent probes for imaging cysteine cathepsin activity<br>Bioorg Med Chem Lett (2025) 132, 130480-130480. PubMed  Europe PubMed DOI
    7. 2024
  7. Giangrieco,I., Ciardiello,M.A., Tamburrini,M., Tuppo,L., Mari,A. and Alessandri,C.<br>Plant and Arthropod IgE-Binding Papain-like Cysteine Proteases: Multiple Contributions to Allergenicity<br>Foods (2024) 13 PubMed  Europe PubMed DOI  PMC  EPMC  V
  8. Rot,A.E., Hrovatin,M., Bokalj,B., Lavrih,E. and Turk,B.<br>Cysteine cathepsins: From diagnosis to targeted therapy of cancer<br>Biochimie (2024) PubMed  Europe PubMed DOI  V
    9. 2023
  9. Cheng,X.W., Narisawa,M., Wang,H. and Piao,L.<br>Overview of multifunctional cysteinyl cathepsins in atherosclerosis-based cardiovascular disease: from insights into molecular functions to clinical implications<br>Cell Biosci (2023) 13, 91-91. PubMed  Europe PubMed DOI  PMC  EPMC  V
  10. Gul,I., Abbas,M.N., Kausar,S., Luo,J., Gao,X., Mu,Y., Fan,W. and Cui,H.<br>Insight into crustacean cathepsins: Structure-evolutionary relationships and functional roles in physiological processes<br>Fish Shellfish Immunol (2023) 139, 108852-108852. PubMed  Europe PubMed DOI  V
  11. Hua,T., Robitaille,M., Roberts-Thomson,S.J. and Monteith,G.R.<br>The intersection between cysteine proteases, Ca(2+) signalling and cancer cell apoptosis<br>Biochim Biophys Acta Mol Cell Res (2023) 1870, 119532-119532. PubMed  Europe PubMed DOI  V
    12. 2022
  12. Anes,E., Pires,D., Mandal,M. and Azevedo-Pereira,J.M.<br>Spatial localization of cathepsins: Implications in immune activation and resolution during infections<br>Front Immunol (2022) 13, 955407-955407. PubMed  Europe PubMed DOI  PMC  EPMC  V
  13. Biasizzo,M., Javorsek,U., Vidak,E., Zaric,M. and Turk,B.<br>Cysteine cathepsins: A long and winding road towards clinics<br>Mol Aspects Med (2022) 88, 101150-101150. PubMed  Europe PubMed DOI  V
  14. Guan,Y., Yang,X., Zhao,R., Li,B., Yang,Z., Gao,M., Cao,X. and Jiang,C.<br>Characteristics of cathepsin members and expression responses to poly I:C challenge in Pacific cod (Gadus macrocephalus)<br>Fish Shellfish Immunol (2022) 128, 484-493. PubMed  Europe PubMed DOI
    15. 2020
  15. Pislar,A., Mitrovic,A., Sabotic,J., Pecar Fonovic,U., Perisic Nanut,M., Jakos,T., Senjor,E. and Kos,J.<br>The role of cysteine peptidases in coronavirus cell entry and replication: The therapeutic potential of cathepsin inhibitors<br>PLoS Pathog (2020) 16, e1009013-e1009013. PubMed  Europe PubMed DOI  PMC  EPMC  V
  16. Yuan,S., Ke,D., Li,R., Li,X., Wang,L., Chen,H., Zhang,C., Huang,Y., Chen,L., Hao,Q., Yang,H., Cao,D., Chen,S., Guo,W., Shan,Z., Yang,Z., Zhang,X., Qiu,D., Guan,Y. and Zhou,X.<br>Genome-wide survey of soybean papain-like cysteine proteases and their expression analysis in root nodule symbiosis<br>BMC Plant Biol (2020) 20, 517-517. PubMed  Europe PubMed DOI  PMC  EPMC
    17. 2018
  17. Liu,J., Sharma,A., Niewiara,M.J., Singh,R., Ming,R. and Yu,Q.<br>Papain-like cysteine proteases in Carica papaya: lineage-specific gene duplication and expansion<br>BMC Genomics (2018) 19, 26-26. PubMed  Europe PubMed DOI  PMC  EPMC
  18. Wang,W., Zhou,X.M., Xiong,H.X., Mao,W.Y., Zhao,P. and Sun,M.X.<br>Papain-like and legumain-like proteases in rice: genome-wide identification, comprehensive gene feature characterization and expression analysis<br>BMC Plant Biol (2018) 18, 87-87. PubMed  Europe PubMed DOI  PMC  EPMC
    19. 2016
  19. Misas-Villamil,J.C., Van Der Hoorn,R.A. and Doehlemann,G.<br>Papain-like cysteine proteases as hubs in plant immunity<br>New Phytol (2016) 212, 902-907. PubMed  Europe PubMed DOI  V
    20. 2015
  20. Saikhedkar,N., Summanwar,A., Joshi,R. and Giri,A.<br>Cathepsins of lepidopteran insects: aspects and prospects<br>Insect Biochem Mol Biol (2015) 64, 51-59. PubMed  Europe PubMed DOI
    21. 2014
  21. Diaz-Mendoza,M., Velasco-Arroyo,B., Gonzalez-Melendi,P., Martinez,M. and Diaz,I.<br>C1A cysteine protease-cystatin interactions in leaf senescence<br>J Exp Bot (2014) 65, 3825-3833. PubMed  Europe PubMed DOI
  22. Santamaria,M.E., Diaz-Mendoza,M., Diaz,I. and Martinez,M.<br>Plant protein peptidase inhibitors: an evolutionary overview based on comparative genomics<br>BMC Genomics (2014) 15, 812-812. PubMed  Europe PubMed DOI
    23. 2012
  23. Nandi,T.K., Bairagya,H.R., Mishra,D.K., Mukhopadhyay,B.P. and Banerjee,A.<br>Structural and putative functional role of conserved water molecular cluster in the X-ray structures of plant thiol proteases: a molecular dynamics simulation study<br>J Chem Crystallogr (2012) 42, 1105-1118. DOI
  24. Richau,K.H., Kaschani,F., Verdoes,M., Pansuriya,T.C., Niessen,S., Stuber,K., Colby,T., Overkleeft,H.S., Bogyo,M. and Van Der Hoorn,R.A.<br>Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics<br>Plant Physiol (2012) 158, 1583-1599. PubMed  Europe PubMed DOI  I
    25. 2009
  25. Nandi,T.K., Bairagya,H.R., Mukhopadhyay,B.P., Sekar,K., Sukul,D. and Bera,A.K.<br>Conserved water-mediated H-bonding dynamics of catalytic Asn 175 in plant thiol protease<br>J Biosci (2009) 34, 27-34. PubMed  Europe PubMed DOI
  26. Smith,G.P., Baustian,K.J., Ackerson,C.J. and Feldheim,D.L.<br>Metal oxide formation by serine and cysteine proteases<br>J Mater Chem (2009) 19, 8299-8306. DOI
  27. Xiao,K., Jehle,F., Peters,C., Reinheckel,T., Schirmer,R.H. and Dandekar,T.<br>CA/C1 peptidases of the malaria parasites Plasmodium falciparum and P. berghei and their mammalian hosts - a bioinformatical analysis<br>Biol Chem (2009) 390, 1185-1197. PubMed  Europe PubMed DOI
    28. 2008
  28. Fairhead,M., Johnson,K.A., Kowatz,T., McMahon,S.A., Carter,L.G., Oke,M., Liu,H., Naismith,J.H. and van der Walle,C.F.<br>Crystal structure and silica condensing activities of silicatein alpha-cathepsin L chimeras<br>Chem Commun (Camb) (2008) 2008, 1765-1767. PubMed  Europe PubMed DOI  S
  29. Shabab,M., Shindo,T., Gu,C., Kaschani,F., Pansuriya,T., Chintha,R., Harzen,A., Colby,T., Kamoun,S. and Van Der Hoorn,R.A.<br>Fungal effector protein AVR2 targets diversifying defense-related Cys proteases of tomato<br>Plant Cell (2008) 20, 1169-1183. PubMed  Europe PubMed DOI  PMC  EPMC
    30. 2006
  30. [YEAR:6-3-2006]Choe,Y., Leonetti,F., Greenbaum,D.C., Lecaille,F., Bogyo,M., Bromme,D., Ellman,J.A. and Craik,C.S.<br>Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities<br>J Biol Chem (6-3-2006) 281, 12824-12832. PubMed  Europe PubMed DOI  P
    31. 2004
  31. Beers,E.P., Jones,A.M. and Dickerman,A.W.<br>The S8 serine, C1A cysteine and A1 aspartic protease families in Arabidopsis<br>Phytochemistry (2004) 65, 43-58. PubMed  Europe PubMed DOI
    32. 2003
  32. [YEAR:28-11-2003]Hodder,A.N., Drew,D.R., Epa,V.C., Delorenzi,M., Bourgon,R., Miller,S.K., Moritz,R.L., Frecklington,D.F., Simpson,R.J., Speed,T.P., Pike,R.N. and Crabb,B.S.<br>Enzymic, phylogenetic, and structural characterization of the unusual papain-like protease domain of Plasmodium falciparum SERA5<br>J Biol Chem (28-11-2003) 278, 48169-48177. PubMed  Europe PubMed DOI
  33. [YEAR:15-6-2003]Hussain,S., Pinitglang,S., Bailey,T.S., Reid,J.D., Noble,M.A., Resmini,M., Thomas,E.W., Greaves,R.B., Verma,C.S. and Brocklehurst,K.<br>Variation in the pH-dependent pre-steady-state and steady-state kinetic characteristics of cysteine-proteinase mechanism: evidence for electrostatic modulation of catalytic-site function by the neighbouring carboxylate anion<br>Biochem J (15-6-2003) 372, 735-746. PubMed  Europe PubMed DOI  PMC  EPMC
  34. Nagler,D.K. and Menard,R.<br>Family C1 cysteine proteases: biological diversity or redundancy?<br>Biol Chem (2003) 384, 837-843. PubMed  Europe PubMed DOI
  35. Uinuk-Ool,T.S., Takezaki,N., Kuroda,N., Figueroa,F., Sato,A., Samonte,I.E., Mayer,W.E. and Klein,J.<br>Phylogeny of antigen-processing enzymes: cathepsins of a cephalochordate, an agnathan and a bony fish<br>Scand J Immunol (2003) 58, 436-448. PubMed  Europe PubMed DOI
    36. 1999
  36. Tort,J., Brindley,P.J., Knox,D., Wolfe,K.H. and Dalton,J.P.<br>Proteinases and associated genes of parasitic helminths<br>Adv Parasitol (1999) 43, 161-266. PubMed  Europe PubMed  V
    37. 1993
  37. [YEAR:1-4-1993]Karrer,K.M., Peiffer,S.L. and DiTomas,M.E.<br>Two distinct gene subfamilies within the family of cysteine protease genes<br>Proc Natl Acad Sci U S A (1-4-1993) 90, 3063-3067. PubMed  Europe PubMed  PMC  EPMC

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