Literature for peptidase A28.003: DNA-damage inducible protein 2

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature

(Topics flags: I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Liu,K., Hu,S., Wufuer,R., Zhang,Q., Qiu,L., Zhang,Z., Wang,M. and Zhang,Y.
    Deficiency of DDI2 suppresses liver cancer progression by worsening cell survival conditions
    Free Radic Biol Med232, 200-213. PubMed  Europe PubMed DOI
  2. 2024
  3. Conti,B.A., Ruiz,P.D., Broton,C., Blobel,N.J., Kottemann,M.C., Sridhar,S., Lach,F.P., Wiley,T.F., Sasi,N.K., Carroll,T. and Smogorzewska,A.
    RTF2 controls replication repriming and ribonucleotide excision at the replisome
    Nat Commun15, 1943-1943. PubMed  Europe PubMed DOI
  4. 2023
  5. Hu,X., Zou,R., Zhang,Z., Ji,J., Li,J., Huo,X.Y., Liu,D., Ge,M.X., Cui,M.K., Wu,M.Z., Li,Z.P., Wang,Q., Zhang,X. and Zhang,Z.R.
    UBE4A catalyzes NRF1 ubiquitination and facilitates DDI2-mediated NRF1 cleavage
    Biochim Biophys Acta Gene Regul Mech1866, 194937-194937. PubMed  Europe PubMed DOI
  6. Ibtisam,I. and Kisselev,A.F.
    Recovery of proteasome activity in cells pulse-treated with proteasome inhibitors is independent of DDI2
    bioRxiv PubMed  Europe PubMed DOI
  7. Lei,L., Cao,Q., An,G., Lv,Y., Tang,J. and Yang,J.
    DDI2 promotes tumor metastasis and resists antineoplastic drugs-induced apoptosis in colorectal cancer
    Apoptosis28, 458-470. PubMed  Europe PubMed DOI
  8. 2022
  9. Collins,G.A., Sha,Z., Kuo,C.L., Erbil,B. and Goldberg,A.L.
    Mammalian Ddi2 is a shuttling factor containing a retroviral protease domain that influences binding of ubiquitylated proteins and proteasomal degradation
    J Biol Chem298, 101875-101875. PubMed  Europe PubMed DOI
  10. 2020
  11. Gu,Y., Wang,X., Wang,Y., Wang,Y., Li,J. and Yu,F.X.
    Nelfinavir inhibits human DDI2 and potentiates cytotoxicity of proteasome inhibitors
    Cell Signal75, 109775-109775. PubMed  Europe PubMed DOI  I
  12. Motyan,J.A., Miczi,M. and Tozser,J.
    Dimer interface organization is a main determinant of intermonomeric interactions and correlates with evolutionary relationships of retroviral and retroviral-like Ddi1 and Ddi2 proteases
    Int J Mol Sci21, PubMed  Europe PubMed DOI
  13. Northrop,A., Vangala,J.R., Feygin,A. and Radhakrishnan,S.K.
    Disabling the Protease DDI2 Attenuates the Transcriptional Activity of NRF1 and Potentiates Proteasome Inhibitor Cytotoxicity
    Int J Mol Sci21, PubMed  Europe PubMed DOI
  14. 2018
  15. Xiang,Y., Halin,J., Fan,Z., Hu,S., Wang,M., Qiu,L., Zhang,Z., Mattjus,P. and Zhang,Y.
    Topovectorial mechanisms control the juxtamembrane proteolytic processing of Nrf1 to remove its N-terminal polypeptides during maturation of the CNC-bZIP factor
    Toxicol Appl Pharmacol360, 160-184. PubMed  Europe PubMed DOI
  16. 2016
  17. Koizumi,S., Irie,T., Hirayama,S., Sakurai,Y., Yashiroda,H., Naguro,I., Ichijo,H., Hamazaki,J. and Murata,S.
    The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction
    elife5, PubMed  Europe PubMed DOI
  18. Sha,Z. and Goldberg,A.L.
    Reply to Vangala et al.: Complete inhibition of the proteasome reduces new proteasome production by causing Nrf1 aggregation
    Curr Biol26, R836-R836. PubMed  Europe PubMed DOI
  19. Siva,M., Svoboda,M., Veverka,V., Trempe,J.F., Hofmann,K., Kozisek,M., Hexnerova,R., Sedlak,F., Belza,J., Brynda,J., Sacha,P., Hubalek,M., Starkova,J., Flaisigova,I., Konvalinka,J. and Saskova,K.G.
    Human DNA-damage-inducible 2 protein is structurally and functionally distinct from its yeast ortholog
    Sci Rep6, 30443-30443. PubMed  Europe PubMed DOI
  20. 2015
  21. Li,J., Biss,M., Fu,Y., Xu,X., Moore,S.A. and Xiao,W.
    Two duplicated genes DDI2 and DDI3 in budding yeast encode a cyanamide hydratase and are induced by cyanamide
    J Biol Chem290, 12664-12675. PubMed  Europe PubMed DOI