Literature for peptidase A28.003: DNA-damage inducible protein 2

(Topics flags: I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Liu,K., Hu,S., Wufuer,R., Zhang,Q., Qiu,L., Zhang,Z., Wang,M. and Zhang,Y.
   Deficiency of DDI2 suppresses liver cancer progression by worsening cell survival conditions
   Free Radic Biol Med (2025) 232, 200-213. PubMed  Europe PubMed DOI
2024
2. Conti,B.A., Ruiz,P.D., Broton,C., Blobel,N.J., Kottemann,M.C., Sridhar,S., Lach,F.P., Wiley,T.F., Sasi,N.K., Carroll,T. and Smogorzewska,A.
   RTF2 controls replication repriming and ribonucleotide excision at the replisome
   Nat Commun (2024) 15, 1943-1943. PubMed  Europe PubMed DOI  PMC  EPMC
2023
3. Hu,X., Zou,R., Zhang,Z., Ji,J., Li,J., Huo,X.Y., Liu,D., Ge,M.X., Cui,M.K., Wu,M.Z., Li,Z.P., Wang,Q., Zhang,X. and Zhang,Z.R.
   UBE4A catalyzes NRF1 ubiquitination and facilitates DDI2-mediated NRF1 cleavage
   Biochim Biophys Acta Gene Regul Mech (2023) 1866, 194937-194937. PubMed  Europe PubMed DOI
4. Ibtisam,I. and Kisselev,A.F.
   Recovery of proteasome activity in cells pulse-treated with proteasome inhibitors is independent of DDI2
   bioRxiv (2023) PubMed  Europe PubMed DOI  PMC  EPMC
5. Lei,L., Cao,Q., An,G., Lv,Y., Tang,J. and Yang,J.
   DDI2 promotes tumor metastasis and resists antineoplastic drugs-induced apoptosis in colorectal cancer
   Apoptosis (2023) 28, 458-470. PubMed  Europe PubMed DOI
2022
6. Collins,G.A., Sha,Z., Kuo,C.L., Erbil,B. and Goldberg,A.L.
   Mammalian Ddi2 is a shuttling factor containing a retroviral protease domain that influences binding of ubiquitylated proteins and proteasomal degradation
   J Biol Chem (2022) 298, 101875-101875. PubMed  Europe PubMed DOI  PMC  EPMC
2020
7. Gu,Y., Wang,X., Wang,Y., Wang,Y., Li,J. and Yu,F.X.
   Nelfinavir inhibits human DDI2 and potentiates cytotoxicity of proteasome inhibitors
   Cell Signal (2020) 75, 109775-109775. PubMed  Europe PubMed DOI  I
8. Motyan,J.A., Miczi,M. and Tozser,J.
   Dimer interface organization is a main determinant of intermonomeric interactions and correlates with evolutionary relationships of retroviral and retroviral-like Ddi1 and Ddi2 proteases
   Int J Mol Sci (2020) 21 PubMed  Europe PubMed DOI
9. Northrop,A., Vangala,J.R., Feygin,A. and Radhakrishnan,S.K.
   Disabling the Protease DDI2 Attenuates the Transcriptional Activity of NRF1 and Potentiates Proteasome Inhibitor Cytotoxicity
   Int J Mol Sci (2020) 21 PubMed  Europe PubMed DOI
2018
10. Xiang,Y., Halin,J., Fan,Z., Hu,S., Wang,M., Qiu,L., Zhang,Z., Mattjus,P. and Zhang,Y.
    Topovectorial mechanisms control the juxtamembrane proteolytic processing of Nrf1 to remove its N-terminal polypeptides during maturation of the CNC-bZIP factor
    Toxicol Appl Pharmacol (2018) 360, 160-184. PubMed  Europe PubMed DOI
2016
11. Koizumi,S., Irie,T., Hirayama,S., Sakurai,Y., Yashiroda,H., Naguro,I., Ichijo,H., Hamazaki,J. and Murata,S.
    The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction
    elife (2016) 5 PubMed  Europe PubMed DOI  PMC  EPMC
12. Sha,Z. and Goldberg,A.L.
    Reply to Vangala et al.: Complete inhibition of the proteasome reduces new proteasome production by causing Nrf1 aggregation
    Curr Biol (2016) 26, R836-R836. PubMed  Europe PubMed DOI
13. Siva,M., Svoboda,M., Veverka,V., Trempe,J.F., Hofmann,K., Kozisek,M., Hexnerova,R., Sedlak,F., Belza,J., Brynda,J., Sacha,P., Hubalek,M., Starkova,J., Flaisigova,I., Konvalinka,J. and Saskova,K.G.
    Human DNA-damage-inducible 2 protein is structurally and functionally distinct from its yeast ortholog
    Sci Rep (2016) 6, 30443-30443. PubMed  Europe PubMed DOI
2015
14. Li,J., Biss,M., Fu,Y., Xu,X., Moore,S.A. and Xiao,W.
    Two duplicated genes DDI2 and DDI3 in budding yeast encode a cyanamide hydratase and are induced by cyanamide
    J Biol Chem (2015) 290, 12664-12675. PubMed  Europe PubMed DOI