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Literature for peptidase A22.014: Psn peptidase (Drosophila-type)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature

(Topics flags: I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Kang,J., Zhang,C., Wang,Y., Peng,J., Berger,B., Perrimon,N. and Shen,J.
    Lipophorin receptors genetically modulate neurodegeneration caused by reduction of Psn expression in the aging Drosophila brain
    Genetics (2024) 226 PubMed  Europe PubMed DOI  PMC  EPMC  K
    2. 2017
  2. Guan,J., Zhang,J., Yuan,S., Yang,B., Clark,K.D., Ling,E. and Huang,W.
    Analysis of the functions of the signal peptidase complex in the midgut of Tribolium castaneum
    Arch Insect Biochem Physiol (2017) 97 PubMed  Europe PubMed DOI
    3. 2015
  3. Zheng,Z.Z., Chao,M.L., Fan,Z.B., Zhao,Y.J. and Song,H.S.
    Molecular cloning and characterization of presenilin gene in Bombyx mori
    Mol Med Rep (2015) 12, 5508-5516. PubMed  Europe PubMed DOI
    4. 2011
  4. Zhang,Y., Zheng,Z.Z., Ge,J., Zhang,H.Y., Huang,Y.W. and Song,H.S.
    [Advances on Drosophila presenilin gene]
    Yi Chuan (2011) 33, 1164-1170. PubMed  Europe PubMed  K
    5. 2010
  5. Groth,C., Alvord,W.G., Quinones,O.A. and Fortini,M.E.
    Pharmacological analysis of Drosophila melanogaster gamma-secretase with respect to differential proteolysis of Notch and APP
    Mol Pharmacol (2010) 77, 567-574. PubMed  Europe PubMed DOI
    6. 2009
  6. Barakat,A., Mercer,B., Cooper,E. and Chung,H.M.
    Examining requirement for formation of functional presenilin proteins and their processing events in vivo
    Genesis (2009) 47, 161-168. PubMed  Europe PubMed DOI
  7. Cooper,E., Deng,W.M. and Chung,H.M.
    Aph-1 is required to regulate presenilin-mediated gamma-secretase activity and cell survival in Drosophila wing development
    Genesis (2009) 47, 169-174. PubMed  Europe PubMed DOI  PMC  EPMC
    8. 2007
  8. Knight,D., Iliadi,K., Charlton,M.P., Atwood,H.L. and Boulianne,G.L.
    Presynaptic plasticity and associative learning are impaired in a Drosophila presenilin null mutant
    Dev Neurobiol (2007) 67, 1598-1613. PubMed  Europe PubMed DOI
    9. 2006
  9. [YEAR:4-5-2006]Doglio,L.E., Kanwar,R., Jackson,G.R., Perez,M., Avila,J., Dingwall,C., Dotti,C.G., Fortini,M.E. and Feiguin,F.
    gamma-Cleavage-independent functions of presenilin, nicastrin, and Aph-1 regulate cell-junction organization and prevent Tau toxicity in vivo
    Neuron (4-5-2006) 50, 359-375. PubMed  Europe PubMed DOI
    10. 2005
  10. [YEAR:11-1-2005]Niimura,M., Isoo,N., Takasugi,N., Tsuruoka,M., Ui-Tei,K., Saigo,K., Morohashi,Y., Tomita,T. and Iwatsubo,T.
    Aph-1 contributes to the stabilization and trafficking of the gamma-secretase complex through mechanisms involving intermolecular and intramolecular interactions
    J Biol Chem (11-1-2005) 280, 12967-12975. PubMed  Europe PubMed DOI
    11. 2004
  11. [YEAR:6-2-2004]Lee,S.F., Shah,S., Yu,C., Wigley,W.C., Li,H., Lim,M., Pedersen,K., Han,W., Thomas,P., Lundkvist,J., Hao,Y.H. and Yu,G.
    A conserved GXXXG motif in APH-1 is critical for assembly and activity of the gamma-secretase complex
    J Biol Chem (6-2-2004) 279, 4144-4152. PubMed  Europe PubMed DOI
  12. Loewer,A., Soba,P., Beyreuther,K., Paro,R. and Merdes,G.
    Cell-type-specific processing of the amyloid precursor protein by presenilin during Drosophila development
    EMBO Rep (2004) 5, 405-411. PubMed  Europe PubMed DOI  PMC  EPMC
    13. 2003
  13. [YEAR:26-5-2003]Hu,Y. and Fortini,M.E.
    Different cofactor activities in gamma-secretase assembly: evidence for a nicastrin-Aph-1 subcomplex
    J Cell Biol (26-5-2003) 161, 685-690. PubMed  Europe PubMed DOI  PMC  EPMC
  14. Micchelli,C.A., Esler,W.P., Kimberly,W.T., Jack,C., Berezovska,O., Kornilova,A., Hyman,B.T., Perrimon,N. and Wolfe,M.S.
    gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila
    FASEB J (2003) 17, 79-81. PubMed  Europe PubMed DOI  I
  15. [YEAR:27-3-2003]Takasugi,N., Tomita,T., Hayashi,I., Tsuruoka,M., Niimura,M., Takahashi,Y., Thinakaran,G. and Iwatsubo,T.
    The role of presenilin cofactors in the gamma-secretase complex
    Nature (27-3-2003) 422, 438-441. PubMed  Europe PubMed DOI
    16. 2002
  16. [YEAR:20-12-2002]Takasugi,N., Takahashi,Y., Morohashi,Y., Tomita,T. and Iwatsubo,T.
    The mechanism of gamma-secretase activities through high molecular weight complex formation of presenilins is conserved in Drosophila melanogaster and mammals
    J Biol Chem (20-12-2002) 277, 50198-50205. PubMed  Europe PubMed DOI
    17. 2001
  17. Chung,H.M. and Struhl,G.
    Nicastrin is required for presenilin-mediated transmembrane cleavage in Drosophila
    Nat Cell Biol (2001) 3, 1129-1132. PubMed  Europe PubMed DOI
  18. [YEAR:2-1-2001]Struhl,G. and Greenwald,I.
    Presenilin-mediated transmembrane cleavage is required for Notch signal transduction in Drosophila
    Proc Natl Acad Sci U S A (2-1-2001) 98, 229-234. PubMed  Europe PubMed DOI  PMC  EPMC
  19. [YEAR:31-8-2001]Tomita,T., Watabiki,T., Takikawa,R., Morohashi,Y., Takasugi,N., Kopan,R., De Strooper,B. and Iwatsubo,T.
    The first proline of PALP motif at the C terminus of presenilins is obligatory for stabilization, complex formation, and gamma-secretase activities of presenilins
    J Biol Chem (31-8-2001) 276, 33273-33281. PubMed  Europe PubMed DOI
    20. 1999
  20. Annaert,W. and De Strooper,B.
    Presenilins: molecular switches between proteolysis and signal transduction
    Trends Neurosci (1999) 22, 439-443. PubMed  Europe PubMed DOI  V

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