Literature for peptidase A22.004: signal peptide peptidase-like protein 2B

(Topics flags: S Structure, K Knockout, P Specificity, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2023
1. Ballin,M., Griep,W., Patel,M., Karl,M., Mentrup,T., Rivera-Monroy,J., Foo,B., Schwappach,B. and Schroder,B.
   The intramembrane proteases SPPL2a and SPPL2b regulate the homeostasis of selected SNARE proteins
   FEBS J290, 2320-2337. PubMed  Europe PubMed DOI
2022
2. Travnickova,K. and Strisovsky,K.
   On the track of intramembrane clippers: the SPPL2a/b proteases caught in the act in animal models
   FEBS J PubMed  Europe PubMed DOI
2019
3. Mentrup,T., Theodorou,K., Cabrera-Cabrera,F., Helbig,A.O., Happ,K., Gijbels,M., Gradtke,A.C., Rabe,B., Fukumori,A., Steiner,H., Tholey,A., Fluhrer,R., Donners,M. and Schroder,B.
   Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis
   J Exp Med216, 807-830. PubMed  Europe PubMed DOI
4. Mentrup,T. and Schroder,B.
   Intramembrane proteases protect from atherosclerosis
   Aging (Albany NY)11, 8041-8043. PubMed  Europe PubMed DOI
2016
5. Fleck,D., Voss,M., Brankatschk,B., Giudici,C., Hampel,H., Schwenk,B., Edbauer,D., Fukumori,A., Steiner,H., Kremmer,E., Haug-Kroper,M., Rossner,M.J., Fluhrer,R., Willem,M. and Haass,C.
   Proteolytic processing of neuregulin 1 type III by three intramembrane-cleaving proteases
   J Biol Chem291, 318-333. PubMed  Europe PubMed DOI  P
2014
6. Schneppenheim,J., Huttl,S., Mentrup,T., Lullmann-Rauch,R., Rothaug,M., Engelke,M., Dittmann,K., Dressel,R., Araki,M., Araki,K., Wienands,J., Fluhrer,R., Saftig,P. and Schroder,B.
   The intramembrane proteases signal peptide peptidase-like 2a and 2b have distinct functions in vivo
   Mol Cell Biol34, 1398-1411. PubMed  Europe PubMed DOI  K
2013
7. Voss,M., Schroder,B. and Fluhrer,R.
   Mechanism, specificity, and physiology of signal peptide peptidase (SPP) and SPP-like proteases
   Biochim Biophys Acta1828, 2828-2839. PubMed  Europe PubMed DOI
8. Zahn,C., Kaup,M., Fluhrer,R. and Fuchs,H.
   The transferrin receptor-1 membrane stub undergoes intramembrane proteolysis by signal peptide peptidase-like 2b
   FEBS J280, 1653-1663. PubMed  Europe PubMed DOI
2012
9. Fluhrer,R., Martin,L., Klier,B., Haug-Kroper,M., Grammer,G., Nuscher,B. and Haass,C.
   The alpha-helical content of the transmembrane domain of the British dementia protein-2 (Bri2) determines its processing by signal peptide peptidase-like 2b (SPPL2b)
   J Biol Chem287, 5156-5163. PubMed  Europe PubMed DOI
2009
10. Golde,T.E., Wolfe,M.S. and Greenbaum,D.C.
    Signal peptide peptidases: a family of intramembrane-cleaving proteases that cleave type 2 transmembrane proteins
    Semin Cell Dev Biol20, 225-230. PubMed  Europe PubMed DOI  V
11. Martin,L., Fluhrer,R. and Haass,C.
    Substrate requirements for SPPL2b-dependent regulated intramembrane proteolysis
    J Biol Chem284, 5662-5670. PubMed  Europe PubMed DOI  S
2008
12. Fluhrer,R., Fukumori,A., Martin,L., Grammer,G., Haug-Kroper,M., Klier,B., Winkler,E., Kremmer,E., Condron,M.M., Teplow,D.B., Steiner,H. and Haass,C.
    Intramembrane proteolysis of GxGD-type aspartyl proteases is slowed by a familial Alzheimer disease-like mutation
    J Biol Chem283, 30121-30128. PubMed  Europe PubMed DOI
13. Martin,L., Fluhrer,R., Reiss,K., Kremmer,E., Saftig,P. and Haass,C.
    Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b
    J Biol Chem283, 1644-1652. PubMed  Europe PubMed DOI
2007
14. Fluhrer,R. and Haass,C.
    Signal peptide peptidases and gamma-secretase: cousins of the same protease family?
    Neurodegener Dis4, 112-116. PubMed  Europe PubMed DOI  V
2006
15. [YEAR:9-7-2006]Fluhrer,R., Grammer,G., Israel,L., Condron,M.M., Haffner,C., Friedmann,E., Bohland,C., Imhof,A., Martoglio,B., Teplow,D.B. and Haass,C.
    A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b
    Nat Cell Biol8, 894-896. PubMed  Europe PubMed DOI
16. [YEAR:9-7-2006]Friedmann,E., Hauben,E., Maylandt,K., Schleeger,S., Vreugde,S., Lichtenthaler,S.F., Kuhn,P.H., Stauffer,D., Rovelli,G. and Martoglio,B.
    SPPL2a and SPPL2b promote intramembrane proteolysis of TNFalpha in activated dendritic cells to trigger IL-12 production
    Nat Cell Biol8, 843-848. PubMed  Europe PubMed DOI
17. Haffner,C. and Haass,C.
    Cellular functions of gamma-secretase-related proteins
    Neurodegener Dis3, 284-289. PubMed  Europe PubMed DOI
18. Nyborg,A.C., Ladd,T.B., Jansen,K., Kukar,T. and Golde,T.E.
    Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase
    FASEB J20, 1671-1679. PubMed  Europe PubMed DOI
2005
19. [YEAR:12-7-2005]Krawitz,P., Haffner,C., Fluhrer,R., Steiner,H., Schmid,B. and Haass,C.
    Differential localization and identification of a critical aspartate suggest non-redundant proteolytic functions of the presenilin homologues SPPL2b and SPPL3
    J Biol Chem280, 39515-39523. PubMed  Europe PubMed DOI
2004
20. [YEAR:21-9-2004]Friedmann,E., Lemberg,M.K., Weihofen,A., Dev,K.K., Dengler,U., Rovelli,G. and Martoglio,B.
    Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins
    J Biol Chem279, 50790-50798. PubMed  Europe PubMed DOI
2002
21. Grigorenko,A.P., Moliaka,Y.K., Korovaitseva,G.I. and Rogaev,E.I.
    Novel class of polytopic proteins with domains associated with putative protease activity
    Biochemistry (Mosc)67, 826-835. PubMed  Europe PubMed DOI