Literature for family A1 unassigned peptidases

(Topics flags: P Specificity, I Inhibitor, E Expression. To select only the references relevant to a single topic, click the link above. See explanation.)

2024
1. Almuqdadi,H.T.A., Kifayat,S., Anwer,R., Alrehaili,J. and Abid,M.
   Fragment-based virtual screening identifies novel leads against Plasmepsin IX (PlmIX) of Plasmodium falciparum: Homology modeling, molecular docking, and simulation approaches
   Front Pharmacol15, 1387629-1387629. PubMed  Europe PubMed DOI
2. Chua,W., Marsh,C.O., Poh,S.E., Koh,W.L., Lee,M.L.Y., Koh,L.F., Tang,X.E., See,P., Ser,Z., Wang,S.M., Sobota,R.M., Dawson,T.L., Jr., Yew,Y.W., Thng,S., O'Donoghue,A.J., Oon,H.H., Common,J.E. and Li,H.
   A Malassezia pseudoprotease dominates the secreted hydrolase landscape and is a potential allergen on skin
   Biochimie216, 181-193. PubMed  Europe PubMed DOI
3. Lisauskaite,M., Nixon,G.L., Woodley,C.M., Berry,N.G., Coninckx,A., Qie,L.C., Leung,S.C., Taramelli,D., Basilico,N., Parapini,S., Ward,S.A., Vadas,O., Soldati-Favre,D., Hong,W.D. and O'Neill,P.M.
   Design, synthesis and modelling of photoreactive chemical probes for investigating target engagement of plasmepsin IX and X in Plasmodium falciparum
   RSC Chem Biol5, 19-29. PubMed  Europe PubMed DOI
4. Mishra,V., Deshmukh,A., Rathore,I., Chakraborty,S., Patankar,S., Gustchina,A., Wlodawer,A., Yada,R.Y. and Bhaumik,P.
   Inhibition of Plasmodium falciparum plasmepsins by drugs targeting HIV-1 protease: A way forward for antimalarial drug discovery
   Curr Res Struct Biol7, 100128-100128. PubMed  Europe PubMed DOI  I
2023
5. Charles,S. and Mahapatra,R.K.
   Artificial intelligence based de-novo design for novel Plasmodium falciparum plasmepsin (PM) X inhibitors
   J Biomol Struct Dyn1-16. PubMed  Europe PubMed DOI
2020
6. Granato,M.Q., Sousa,I.S., Rosa,T.L.S.A., Goncalves,D.S., Seabra,S.H., Alviano,D.S., Pessolani,M.C.V., Santos,A.L.S. and Kneipp,L.F.
   Aspartic peptidase of Phialophora verrucosa as target of HIV peptidase inhibitors: blockage of its enzymatic activity and interference with fungal growth and macrophage interaction
   J Enzyme Inhib Med Chem35, 629-638. PubMed  Europe PubMed DOI  I
7. Guo,Y., Tu,T., Zheng,J., Ren,Y., Wang,Y., Bai,Y., Su,X., Wang,Y., Yao,B., Huang,H. and Luo,H.
   A novel thermostable aspartic protease from Talaromyces leycettanus and its specific autocatalytic activation through an intermediate transition state
   Appl Microbiol Biotechnol104, 4915-4926. PubMed  Europe PubMed DOI
8. Pereira,W.E.S., da Silva,R.R., de Amo,G.S., Ruller,R., Kishi,L.T., Boscolo,M., Gomes,E. and da Silva,R.
   A collagenolytic aspartic protease from Thermomucor indicae-seudaticae expressed in Escherichia coli and Pichia pastoris
   Appl Biochem Biotechnol PubMed  Europe PubMed DOI
9. Poh,S.E., Goh,J.P.Z., Fan,C., Chua,W., Gan,S.Q., Lim,P.L.K., Sharma,B., Leavesley,D.I., Dawson TL Jr and Li,H.
   Identification of Malassezia furfur secreted aspartyl protease 1 (MfSAP1) and its role in extracellular matrix degradation
   Front Cell Infect Microbiol10, 148-148. PubMed  Europe PubMed DOI
10. Shimoda,Y., Nishigaya,Y., Yamaya-Ito,H., Inagaki,N., Umehara,Y., Hirakawa,H., Sato,S., Yamazaki,T. and Hayashi,M.
    The rhizobial autotransporter determines the symbiotic nitrogen fixation activity of Lotus japonicus in a host-specific manner
    Proc Natl Acad Sci U S A117, 1806-1815. PubMed  Europe PubMed DOI
11. Wang,X., Shi,Y., He,R., Li,B. and Huang,A.
    Label-free quantitative proteomic analysis of the biological functions of Moringa oleifera seed proteins provides insights regarding the milk-clotting proteases
    Int J Biol Macromol144, 325-333. PubMed  Europe PubMed DOI
12. Xu,J., Liu,R.D., Bai,S.J., Hao,H.N., Yue,W.W., Xu,Y.X.Y., Long,S.R., Cui,J. and Wang,Z.Q.
    Molecular characterization of a Trichinella spiralis aspartic protease and its facilitation role in larval invasion of host intestinal epithelial cells
    PLoS Negl Trop Dis14, e0008269-e0008269. PubMed  Europe PubMed DOI
2019
13. Guo,B., Wang,H., Yang,B., Jiang,W., Jing,M., Li,H., Xia,Y., Xu,Y., Hu,Q., Wang,F., Yu,F., Wang,Y., Ye,W., Dong,S., Xing,W. and Wang,Y.
    Phytophthora sojae effector PsAvh240 inhibits host aspartic protease secretion to promote infection
    Mol Plant12, 552-564. PubMed  Europe PubMed DOI
14. Guo,Y., Tu,T., Zheng,J., Bai,Y., Huang,H., Su,X., Wang,Y., Wang,Y., Yao,B. and Luo,H.
    Improvement of BsAPA aspartic protease thermostability via autocatalysis-resistant mutation
    J Agric Food Chem67, 10505-10512. PubMed  Europe PubMed DOI
15. Guo,Y., Tu,T., Yuan,P., Wang,Y., Ren,Y., Yao,B. and Luo,H.
    High-level expression and characterization of a novel aspartic protease from Talaromyces leycettanus JCM12802 and its potential application in juice clarification
    Food Chem281, 197-203. PubMed  Europe PubMed DOI
16. Gutierrez-Mendez,N., Balderrama-Carmona,A., Garcia-Sandoval,S.E., Ramirez-Vigil,P., Leal-Ramos,M.Y. and Garcia-Triana,A.
    Proteolysis and rheological properties of cream cheese made with a plant-derived coagulant from Solanum elaeagnifolium
    Foods8, PubMed  Europe PubMed DOI
17. Osuna-Ruiz,I., Espinoza-Marroquin,M.F., Salazar-Leyva,J.A., Pena,E., Alvarez-Gonzalez,C.A., Banuelos-Vargas,I. and Martinez-Montano,E.
    Biochemical characterization of a semi-purified aspartic protease from sea catfish Bagre panamensis with milk-clotting activity
    Food Sci Biotechnol28, 1785-1793. PubMed  Europe PubMed DOI
18. Soares,A., Niedermaier,S., Faro,R., Loos,A., Manadas,B., Faro,C., Huesgen,P.F., Cheung,A.Y. and Simoes,I.
    An atypical aspartic protease modulates lateral root development in Arabidopsis thaliana
    J Exp Bot70, 2157-2171. PubMed  Europe PubMed DOI
19. Wan Zakaria,W.N.A., Aizat,W.M., Goh,H.H. and Mohd Noor,N.
    Protein replenishment in pitcher fluids of Nepenthes x ventrata revealed by quantitative proteomics (SWATH-MS) informed by transcriptomics
    J Plant Res132, 681-694. PubMed  Europe PubMed DOI
2018
20. Bialkowska,A.M., Krysiak,J., Florczak,T., Szulczewska,K.M., Wanarska,M. and Turkiewicz,M.
    The psychrotrophic yeast Sporobolomyces roseus LOCK 1119 as a source of a highly active aspartic protease for the in vitro production of antioxidant peptides
    Biotechnol Appl Biochem65, 726-738. PubMed  Europe PubMed DOI
21. Ianiri,G., Heitman,J. and Scheynius,A.
    The skin commensal yeast Malassezia globosa thwarts bacterial biofilms to benefit the host
    J Invest Dermatol138, 1026-1029. PubMed  Europe PubMed DOI
22. Lotfan,M., Choudhary,S., Yadav,M.L., Kumar,S., Singh,S., Bathla,S., Rawat,P., Kaushik,J.K. and Mohanty,A.K.
    Primary structures of different isoforms of buffalo pregnancy-associated glycoproteins (BuPAGs) during early pregnancy and elucidation of the 3-dimensional structure of the most abundant isoform BuPAG 7
    PLoS ONE13, e0206143-e0206143. PubMed  Europe PubMed DOI
23. Santos,A.L.S., Matteoli,F.P., Sangenito,L.S., Branquinha,M.H., Cotrim,B.A. and Resende,G.O.
    Asymmetric peptidomimetics containing L-tartaric acid core inhibit the aspartyl peptidase activity and growth of Leishmania amazonensis promastigotes
    Acta Parasitol63, 114-124. PubMed  Europe PubMed DOI
24. Yamaya-Ito,H., Shimoda,Y., Hakoyama,T., Sato,S., Kaneko,T., Hossain,M.S., Shibata,S., Kawaguchi,M., Hayashi,M., Kouchi,H. and Umehara,Y.
    Loss-of-function of ASPARTIC PEPTIDASE NODULE-INDUCED 1 (APN1) in Lotus japonicus restricts efficient nitrogen-fixing symbiosis with specific Mesorhizobium loti strains
    Plant J93, 5-16. PubMed  Europe PubMed DOI
2017
25. Boddey,J.A.
    Plasmepsins on the antimalarial hit list
    Science358, 445-446. PubMed  Europe PubMed DOI  I
26. Bryksa,B.C., Grahame,D.A. and Yada,R.Y.
    Comparative structure-function characterization of the saposin-like domains from potato, barley, cardoon and Arabidopsis aspartic proteases
    Biochim Biophys Acta1859, 1008-1018. PubMed  Europe PubMed DOI
27. Lipka,A., Majewska,M., Panasiewicz,G., Bieniek-Kobuszewska,M. and Szafranska,B.
    Gene structure of the pregnancy-associated glycoprotein-like (PAG-L) in the Eurasian beaver (Castor fiber L.)
    Funct Integr Genomics17, 599-605. PubMed  Europe PubMed DOI
28. Mastan,B.S., Narwal,S.K., Dey,S., Kumar,K.A. and Mishra,S.
    Plasmodium berghei plasmepsin VIII is essential for sporozoite gliding motility
    Int J Parasitol47, 239-245. PubMed  Europe PubMed DOI
29. Nasamu,A.S., Glushakova,S., Russo,I., Vaupel,B., Oksman,A., Kim,A.S., Fremont,D.H., Tolia,N., Beck,J.R., Meyers,M.J., Niles,J.C., Zimmerberg,J. and Goldberg,D.E.
    Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion
    Science358, 518-522. PubMed  Europe PubMed DOI  I
30. Salehi,M., Aghamaali,M.R., Sajedi,R.H., Asghari,S.M. and Jorjani,E.
    Purification and characterization of a milk-clotting aspartic protease from Withania coagulans fruit
    Int J Biol Macromol98, 847-854. PubMed  Europe PubMed DOI
2016
31. Burggraaf,A.M., Punt,P.J. and Ram,A.F.
    The unconventional secretion of PepN is independent of a functional autophagy machinery in the filamentous fungus Aspergillus niger
    FEMS Microbiol Lett363, fnw152-fnw152. PubMed  Europe PubMed DOI
32. Li,F., Bounkeua,V., Pettersen,K. and Vinetz,J.M.
    Plasmodium falciparum ookinete expression of plasmepsin VII and plasmepsin X
    Malar J15, 111-111. PubMed  Europe PubMed DOI
33. Mandujano-Gonzalez,V., Tellez-Jurado,A., Anducho-Reyes,M.A., Arana-Cuenca,A. and Mercado-Flores,Y.
    Purification and characterization of the extracellular aspartyl protease APSm1 from the phytopathogen fungus Stenocarpella maydis
    Protein Expr Purif117, 1-5. PubMed  Europe PubMed DOI
2014
34. Beigomi,M., Mohammadifar,M.A., Hashemi,M., Rohani,M.G., Senthil,K. and Valizadeh,M.
    Biochemical and rheological characterization of a protease from fruits of Withania coagulans with a milk-clotting activity
    Food Sci Biotechnol23, 1805-1813. DOI
35. Mastan,B.S., Kumari,A., Gupta,D., Mishra,S. and Kumar,K.A.
    Gene disruption reveals a dispensable role for plasmepsin VII in the Plasmodium berghei life cycle
    Mol Biochem Parasitol195, 10-13. PubMed  Europe PubMed DOI
2013
36. Aoki,K., Matsubara,S., Umeda,M., Tachibanac,S., Doi,M. and Takenaka,S.
    Aspartic protease from Aspergillus (Eurotium) repens strain MK82 is involved in the hydrolysis and decolourisation of dried bonito (Katsuobushi)
    J Sci Food Agric93, 1349-1355. PubMed  Europe PubMed DOI  P
37. Huang,J., Zhao,X., Cheng,K., Jiang,Y., Ouyang,Y., Xu,C., Li,X., Xiao,J. and Zhang,Q.
    OsAP65, a rice aspartic protease, is essential for male fertility and plays a role in pollen germination and pollen tube growth
    J Exp Bot64, 3351-3360. PubMed  Europe PubMed DOI
2012
38. Balczun,C., Siemanowski,J., Pausch,J.K., Helling,S., Marcus,K., Stephan,C., Meyer,H.E., Schneider,T., Cizmowski,C., Oldenburg,M., Hohn,S., Meiser,C.K., Schuhmann,W. and Schaub,G.A.
    Intestinal aspartate proteases TiCatD and TiCatD2 of the haematophagous bug Triatoma infestans (Reduviidae): sequence characterisation, expression pattern and characterisation of proteolytic activity
    Insect Biochem Mol Biol42, 240-250. PubMed  Europe PubMed DOI
2011
39. Abd El-Baky,H., Linke,D., Nimtz,M., Metry,W., El-Demerdash,O. and Berger,R.G.
    The extracellular aspartic peptidase of basidiomycete Wolfiporia cocos is a highly efficient milk clotting enzyme
    Milchwissenschaft66, 406-409.
2010
40. Cho,E.Y., Cheon,S.A., Kim,H., Choo,J., Lee,D.J., Ryu,H.M., Rhee,S.K., Chung,B.H., Kim,J.Y. and Kang,H.A.
    Multiple-yapsin-deficient mutant strains for high-level production of intact recombinant proteins in Saccharomyces cerevisiae
    J Biotechnol149, 1-7. PubMed  Europe PubMed DOI
2009
41. Takahashi,K., Matsumoto,K., Nishii,W., Muramatsu,M., Kubota,K., Shibata,C. and Athauda,S.B.P.
    Comparative studies on the acid protenase activities in the digestive fluids of Nepenthes, Cephalotus, Dionaea, and Drosera
    Carniv Pl Newsletter38, 75-82.
1986
42. Yamashita,I., Hirata,D., Machida,M. and Fukui,S.
    Cloning and expression in Saccharomyces cerevisiae of the secretable acid protease gene from Saccharomycopsis fibuligera
    Agric Biol Chem50, 109-113. DOI  E