Literature for peptidase A01.064: candidapepsin SAP6

(Topics flags: A Assay, P Specificity, I Inhibitor, E Expression. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Zawrotniak,M., Satala,D., Juszczak,M., Bras,G. and Rapala-Kozik,M.
   Candida albicans aspartyl protease (Sap6) inhibits neutrophil function via a "Trojan horse" mechanism
   Sci Rep15, 6946-6946. PubMed  Europe PubMed DOI
2022
2. Veni,A., Lokeswari,T.S., Pavithra,D. and Sugapriya,T.
   Melianone inhibits Secreted Aspartic Proteases (SAP), a Virulence Factor During Hyphal Formation in Candida albicans
   Curr Comput Aided Drug Des18, 327-336. PubMed  Europe PubMed DOI  I
2017
3. Kumar,R., Breindel,C., Saraswat,D., Cullen,P.J. and Edgerton,M.
   Candida albicans Sap6 amyloid regions function in cellular aggregation and zinc binding, and contribute to zinc acquisition
   Sci Rep7, 2908-2908. PubMed  Europe PubMed DOI
2016
4. Winter,M.B., Salcedo,E.C., Lohse,M.B., Hartooni,N., Gulati,M., Sanchez,H., Takagi,J., Hube,B., Andes,D.R., Johnson,A.D., Craik,C.S. and Nobile,C.J.
   Global identification of biofilm-specific proteolysis in Candida albicans
   MBio7, PubMed  Europe PubMed DOI  A
2015
5. Kumar,R., Saraswat,D., Tati,S. and Edgerton,M.
   Novel aggregation properties of Candida albicans secreted aspartyl proteinase Sap6 mediate virulence in oral candidiasis
   Infect Immun83, 2614-2626. PubMed  Europe PubMed DOI
2013
6. Buu,L.M. and Chen,Y.C.
   Sap6, a secreted aspartyl proteinase, participates in maintenance the cell surface integrity of Candida albicans
   J Biomed Sci20, 101-101. PubMed  Europe PubMed DOI
7. Pietrella,D., Pandey,N., Gabrielli,E., Pericolini,E., Perito,S., Kasper,L., Bistoni,F., Cassone,A., Hube,B. and Vecchiarelli,A.
   Secreted aspartic proteases of Candida albicans activate the NLRP3 inflammasome
   Eur J Immunol43, 679-692. PubMed  Europe PubMed DOI
8. Wu,H., Downs,D., Ghosh,K., Ghosh,A.K., Staib,P., Monod,M. and Tang,J.
   Candida albicans secreted aspartic proteases 4-6 induce apoptosis of epithelial cells by a novel Trojan horse mechanism
   FASEB J27, 2132-2144. PubMed  Europe PubMed DOI
2012
9. Monod,M., Staib,P. and Borelli,C.
   Candidapepsin
   [ISSN:978-0-12-407744-7]3, 159-166. DOI
2011
10. Aoki,W., Kitahara,N., Miura,N., Morisaka,H., Yamamoto,Y., Kuroda,K. and Ueda,M.
    Comprehensive characterization of secreted aspartic proteases encoded by a virulence gene family in Candida albicans
    J Biochem150, 431-438. PubMed  Europe PubMed DOI  P
2010
11. Correia,A., Lermann,U., Teixeira,L., Cerca,F., Botelho,S., Gil Da Costa,R.M., Sampaio,P., Gartner,F., Morschhauser,J., Vilanova,M. and Pais,C.
    Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis
    Infect Immun78, 4839-4849. PubMed  Europe PubMed DOI
12. Pietrella,D., Rachini,A., Pandey,N., Schild,L., Netea,M., Bistoni,F., Hube,B. and Vecchiarelli,A.
    The Inflammatory response induced by aspartic proteases of Candida albicans is independent of proteolytic activity
    Infect Immun78, 4754-4762. PubMed  Europe PubMed DOI
2009
13. Parra-Ortega,B., Cruz-Torres,H., Villa-Tanaca,L. and Hernandez-Rodriguez,C.
    Phylogeny and evolution of the aspartyl protease family from clinically relevant Candida species
    Mem Inst Oswaldo Cruz104, 505-512. PubMed  Europe PubMed
2008
14. Lermann,U. and Morschhauser,J.
    Secreted aspartic proteases are not required for invasion of reconstituted human epithelia by Candida albicans
    Microbiology (Reading)154, 3281-3295. PubMed  Europe PubMed DOI
15. Naglik,J.R., Moyes,D., Makwana,J., Kanzaria,P., Tsichlaki,E., Weindl,G., Tappuni,A.R., Rodgers,C.A., Woodman,A.J., Challacombe,S.J., Schaller,M. and Hube,B.
    Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis
    Microbiology (Reading)154, 3266-3280. PubMed  Europe PubMed DOI
16. Odds,F.C.
    Secreted proteinases and Candida albicans virulence
    Microbiology (Reading)154, 3245-3246. PubMed  Europe PubMed DOI
17. Staib,P., Lermann,U., Blass-Warmuth,J., Degel,B., Wurzner,R., Monod,M., Schirmeister,T. and Morschhauser,J.
    Tetracycline-inducible expression of individual secreted aspartic proteases in Candida albicans allows isoenzyme-specific inhibitor screening
    Antimicrob Agents Chemother52, 146-156. PubMed  Europe PubMed DOI
2002
18. Felk,A., Kretschmar,M., Albrecht,A., Schaller,M., Beinhauer,S., Nichterlein,T., Sanglard,D., Korting,H.C., Schafer,W. and Hube,B.
    Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs
    Infect Immun70, 3689-3700. PubMed  Europe PubMed DOI
19. Kretschmar,M., Felk,A., Staib,P., Schaller,M., Hess,D., Callapina,M., Morschhauser,J., Schafer,W., Korting,H.C., Hof,H., Hube,B. and Nichterlein,T.
    Individual acid aspartic proteinases (Saps) 1-6 of Candida albicans are not essential for invasion and colonization of the gastrointestinal tract in mice
    Microb Pathog32, 61-70. PubMed  Europe PubMed DOI
2001
20. De Bernardis,F., Sullivan,P.A. and Cassone,A.
    Aspartyl proteinases of Candida albicans and their role in pathogenicity
    Med Mycol39, 303-313. PubMed  Europe PubMed
21. Hube,B. and Naglik,J.
    Candida albicans proteinases: resolving the mystery of a gene family
    Microbiology (Reading, Engl )147, 1997-2005. PubMed  Europe PubMed
22. Schaller,M., Januschke,E., Schackert,C., Woerle,B. and Korting,H.C.
    Different isoforms of secreted aspartyl proteinases (Sap) are expressed by Candida albicans during oral and cutaneous candidosis in vivo
    J Med Microbiol50, 743-747. PubMed  Europe PubMed
2000
23. [YEAR:14-7-2000]Koelsch,G., Tang,J., Loy,J.A., Monod,M., Jackson,K., Foundling,S.I. and Lin,X.L.
    Enzymic characteristics of secreted aspartic proteases of Candida albicans
    Biochim Biophys Acta1480, 117-131. PubMed  Europe PubMed DOI
24. Schaller,M., Schackert,C., Korting,H.C., Januschke,E. and Hube,B.
    Invasion of Candida albicans correlates with expression of secreted aspartic proteinases during experimental infection of human epidermis
    J Invest Dermatol114, 712-717. PubMed  Europe PubMed DOI
25. Stehr,F., Felk,A., Kretschmar,M., Schaller,M., Schafer,W. and Hube,B.
    [Extracellular hydrolytic enzymes and their relevance during Candida albicans infections]
    Mycoses43 Suppl 2, 17-21. PubMed  Europe PubMed
1999
26. Kretschmar,M., Hube,B., Bertsch,T., Sanglard,D., Merker,R., Schroder,M., Hof,H. and Nichterlein,T.
    Germ tubes and proteinase activity contribute to virulence of Candida albicans in murine peritonitis
    Infect Immun67, 6637-6642. PubMed  Europe PubMed
27. Schaller,M., Korting,H.C., Schafer,W., Bastert,J., Chen,W. and Hube,B.
    Secreted aspartic proteinase (Sap) activity contributes to tissue damage in a model of human oral candidosis
    Mol Microbiol34, 169-180. PubMed  Europe PubMed DOI
1998
28. Borg-von Zepelin,M., Beggah,S., Boggian,K., Sanglard,D. and Monod,M.
    The expression of the secreted aspartyl proteinases Sap4 to Sap6 from Candida albicans in murine macrophages
    Mol Microbiol28, 543-554. PubMed  Europe PubMed DOI  E
1997
29. Sanglard,D., Hube,B., Monod,M., Odds,F.C. and Gow,N.A.
    A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence
    Infect Immun65, 3539-3546. PubMed  Europe PubMed
1994
30. Hube,B., Monod,M., Schofield,D.A., Brown,A.J. and Gow,N.A.
    Expression of seven members of the gene family encoding secretory aspartyl proteinases in Candida albicans
    Mol Microbiol14, 87-99. PubMed  Europe PubMed DOI
31. Monod,M., Togni,G., Hube,B. and Sanglard,D.
    Multiplicity of genes encoding secreted aspartic proteinases in Candida species
    Mol Microbiol13, 357-368. PubMed  Europe PubMed DOI