Literature for peptidase A01.063: candidapepsin SAP5

Summary Alignment Sequences Sequence features Distribution Structure Literature

(Topics flags: S Structure, A Assay, P Specificity, I Inhibitor, K Knockout, E Expression. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Prusty,J.S. and Kumar,A.
    In silico-driven identification and experimental confirmation of antifungal proteins (AFPs) against Candidaalbicans
    Biochimie PubMed  Europe PubMed DOI
  2. 2016
  3. Winter,M.B., Salcedo,E.C., Lohse,M.B., Hartooni,N., Gulati,M., Sanchez,H., Takagi,J., Hube,B., Andes,D.R., Johnson,A.D., Craik,C.S. and Nobile,C.J.
    Global identification of biofilm-specific proteolysis in Candida albicans
    MBio7, PubMed  Europe PubMed DOI  A
  4. 2014
  5. Moazeni,M., Khoramizadeh,M.R., Teimoori-Toolabi,L., Noorbakhsh,F. and Rezaie,S.
    The effect of EFG1 gene silencing on down-regulation of SAP5 gene, by use of RNAi technology
    Acta Med Iran52, 9-14. PubMed  Europe PubMed  K
  6. 2013
  7. Cadicamo,C.D., Mortier,J., Wolber,G., Hell,M., Heinrich,I.E., Michel,D., Semlin,L., Berger,U., Korting,H.C., Holtje,H.D., Koksch,B. and Borelli,C.
    Design, synthesis, inhibition studies, and molecular modeling of pepstatin analogues addressing different secreted aspartic proteinases of Candida albicans
    Biochem Pharmacol85, 881-887. PubMed  Europe PubMed DOI  I
  8. Wu,H., Downs,D., Ghosh,K., Ghosh,A.K., Staib,P., Monod,M. and Tang,J.
    Candida albicans secreted aspartic proteases 4-6 induce apoptosis of epithelial cells by a novel Trojan horse mechanism
    FASEB J27, 2132-2144. PubMed  Europe PubMed DOI
  9. 2012
  10. Monod,M., Staib,P. and Borelli,C.
    Candidapepsin
    [ISSN:978-0-12-407744-7]3, 159-166. DOI
  11. Staniszewska,M., Bondaryk,M., Siennicka,K., Pilat,J., Schaller,M. and Kurzatkowski,W.
    Role of aspartic proteinases in Candida albicans virulence. Part II: Expression of SAP1-10 aspartic proteinase during Candida albicans infections in vivo
    Postepy Mikrobiol51, 137-142.
  12. 2011
  13. Aoki,W., Kitahara,N., Miura,N., Morisaka,H., Yamamoto,Y., Kuroda,K. and Ueda,M.
    Comprehensive characterization of secreted aspartic proteases encoded by a virulence gene family in Candida albicans
    J Biochem150, 431-438. PubMed  Europe PubMed DOI  P
  14. 2010
  15. Correia,A., Lermann,U., Teixeira,L., Cerca,F., Botelho,S., Gil Da Costa,R.M., Sampaio,P., Gartner,F., Morschhauser,J., Vilanova,M. and Pais,C.
    Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis
    Infect Immun78, 4839-4849. PubMed  Europe PubMed DOI
  16. 2009
  17. Parra-Ortega,B., Cruz-Torres,H., Villa-Tanaca,L. and Hernandez-Rodriguez,C.
    Phylogeny and evolution of the aspartyl protease family from clinically relevant Candida species
    Mem Inst Oswaldo Cruz104, 505-512. PubMed  Europe PubMed
  18. 2008
  19. Borelli,C., Ruge,E., Lee,J.H., Schaller,M., Vogelsang,A., Monod,M., Korting,H.C., Huber,R. and Maskos,K.
    X-ray structures of Sap1 and Sap5: structural comparison of the secreted aspartic proteinases from Candida albicans
    Proteins72, 1308-1319. PubMed  Europe PubMed DOI  S
  20. Lermann,U. and Morschhauser,J.
    Secreted aspartic proteases are not required for invasion of reconstituted human epithelia by Candida albicans
    Microbiology (Reading)154, 3281-3295. PubMed  Europe PubMed DOI
  21. Naglik,J.R., Moyes,D., Makwana,J., Kanzaria,P., Tsichlaki,E., Weindl,G., Tappuni,A.R., Rodgers,C.A., Woodman,A.J., Challacombe,S.J., Schaller,M. and Hube,B.
    Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis
    Microbiology (Reading)154, 3266-3280. PubMed  Europe PubMed DOI
  22. Odds,F.C.
    Secreted proteinases and Candida albicans virulence
    Microbiology (Reading)154, 3245-3246. PubMed  Europe PubMed DOI
  23. Staib,P., Lermann,U., Blass-Warmuth,J., Degel,B., Wurzner,R., Monod,M., Schirmeister,T. and Morschhauser,J.
    Tetracycline-inducible expression of individual secreted aspartic proteases in Candida albicans allows isoenzyme-specific inhibitor screening
    Antimicrob Agents Chemother52, 146-156. PubMed  Europe PubMed DOI
  24. 2007
  25. Villar,C.C., Kashleva,H., Nobile,C.J., Mitchell,A.P. and Dongari-Bagtzoglou,A.
    Mucosal tissue invasion by Candida albicans is associated with E-cadherin degradation, mediated by transcription factor Rim101p and protease Sap5p
    Infect Immun75, 2126-2135. PubMed  Europe PubMed DOI
  26. 2002
  27. Felk,A., Kretschmar,M., Albrecht,A., Schaller,M., Beinhauer,S., Nichterlein,T., Sanglard,D., Korting,H.C., Schafer,W. and Hube,B.
    Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs
    Infect Immun70, 3689-3700. PubMed  Europe PubMed DOI
  28. Kretschmar,M., Felk,A., Staib,P., Schaller,M., Hess,D., Callapina,M., Morschhauser,J., Schafer,W., Korting,H.C., Hof,H., Hube,B. and Nichterlein,T.
    Individual acid aspartic proteinases (Saps) 1-6 of Candida albicans are not essential for invasion and colonization of the gastrointestinal tract in mice
    Microb Pathog32, 61-70. PubMed  Europe PubMed DOI
  29. Staib,P., Kretschmar,M., Nichterlein,T., Hof,H. and Morschhauser,J.
    Transcriptional regulators Cph1p and Efg1p mediate activation of the Candida albicans virulence gene SAP5 during infection
    Infect Immun70, 921-927. PubMed  Europe PubMed DOI
  30. 2001
  31. De Bernardis,F., Sullivan,P.A. and Cassone,A.
    Aspartyl proteinases of Candida albicans and their role in pathogenicity
    Med Mycol39, 303-313. PubMed  Europe PubMed
  32. Hube,B. and Naglik,J.
    Candida albicans proteinases: resolving the mystery of a gene family
    Microbiology (Reading, Engl )147, 1997-2005. PubMed  Europe PubMed
  33. Schaller,M., Januschke,E., Schackert,C., Woerle,B. and Korting,H.C.
    Different isoforms of secreted aspartyl proteinases (Sap) are expressed by Candida albicans during oral and cutaneous candidosis in vivo
    J Med Microbiol50, 743-747. PubMed  Europe PubMed
  34. 2000
  35. Schaller,M., Schackert,C., Korting,H.C., Januschke,E. and Hube,B.
    Invasion of Candida albicans correlates with expression of secreted aspartic proteinases during experimental infection of human epidermis
    J Invest Dermatol114, 712-717. PubMed  Europe PubMed DOI
  36. Stehr,F., Felk,A., Kretschmar,M., Schaller,M., Schafer,W. and Hube,B.
    [Extracellular hydrolytic enzymes and their relevance during Candida albicans infections]
    Mycoses43 Suppl 2, 17-21. PubMed  Europe PubMed
  37. 1999
  38. Kretschmar,M., Hube,B., Bertsch,T., Sanglard,D., Merker,R., Schroder,M., Hof,H. and Nichterlein,T.
    Germ tubes and proteinase activity contribute to virulence of Candida albicans in murine peritonitis
    Infect Immun67, 6637-6642. PubMed  Europe PubMed
  39. Schaller,M., Korting,H.C., Schafer,W., Bastert,J., Chen,W. and Hube,B.
    Secreted aspartic proteinase (Sap) activity contributes to tissue damage in a model of human oral candidosis
    Mol Microbiol34, 169-180. PubMed  Europe PubMed DOI
  40. 1998
  41. Borg-von Zepelin,M., Beggah,S., Boggian,K., Sanglard,D. and Monod,M.
    The expression of the secreted aspartyl proteinases Sap4 to Sap6 from Candida albicans in murine macrophages
    Mol Microbiol28, 543-554. PubMed  Europe PubMed DOI  E
  42. 1997
  43. Sanglard,D., Hube,B., Monod,M., Odds,F.C. and Gow,N.A.
    A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence
    Infect Immun65, 3539-3546. PubMed  Europe PubMed
  44. 1994
  45. Hube,B., Monod,M., Schofield,D.A., Brown,A.J. and Gow,N.A.
    Expression of seven members of the gene family encoding secretory aspartyl proteinases in Candida albicans
    Mol Microbiol14, 87-99. PubMed  Europe PubMed DOI
  46. Monod,M., Togni,G., Hube,B. and Sanglard,D.
    Multiplicity of genes encoding secreted aspartic proteinases in Candida species
    Mol Microbiol13, 357-368. PubMed  Europe PubMed DOI