Literature for peptidase A01.021: plasmepsin (Plasmodium sp.)

(Topics flags: S Structure, I Inhibitor, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2020

Cheuka,P.M., Dziwornu,G., Okombo,J. and Chibale,K. Plasmepsin Inhibitors in Antimalarial Drug Discovery: Medicinal Chemistry and Target Validation (2000 to Present) J Med Chem (2020) 63, 4445-4467. PubMed Europe PubMed DOI

2019

Bobrovs,R., Jaudzems,K. and Jirgensons,A. Exploiting structural dynamics to design open-flap inhibitors of malarial aspartic proteases J Med Chem (2019) 62, 8931-8950. PubMed Europe PubMed DOI I

2014

Kumar,S., Briguglio,J.S. and Turkewitz,A.P. An aspartyl cathepsin, CTH3, is essential for proprotein processing during secretory granule maturation in Tetrahymena thermophila Mol Biol Cell (2014) 25, 2444-2460. PubMed Europe PubMed DOI

2012

Berry,C. and Goldberg,D.E. Food vacuole plasmepsins [ISSN:978-0-12-407744-7] (2012) 3, 98-103. DOI
Meyers,M.J. and Goldberg,D.E. Recent advances in plasmepsin medicinal chemistry and implications for future antimalarial drug discovery efforts Curr Top Med Chem (2012) 12, 445-455. PubMed Europe PubMed DOI I

2006

[YEAR:2-12-2006]Martins,T.M., Domingos,A., Berry,C. and Wyatt,D.M. The activity and inhibition of the food vacuole plasmepsin from the rodent malaria parasite Plasmodium chabaudi Acta Trop (2-12-2006) 97, 212-218. PubMed Europe PubMed DOI

2005

Sharma,A., Eapen,A. and Subbarao,S.K. Purification and characterization of a hemoglobin degrading aspartic protease from the malarial parasite Plasmodium vivax J Biochem (2005) 138, 71-78. PubMed Europe PubMed DOI

2004

Berry,C. and Goldberg,D.E. Plasmepsins [ISSN:0-12-079610-4] (2004) 2, 70-73. V
Na,B.K., Lee,E.G., Lee,H.W., Cho,S.H., Bae,Y.A., Kong,Y., Lee,J.K. and Kim,T.S. Aspartic proteases of Plasmodium vivax are highly conserved in wild isolates Korean J Parasitol (2004) 42, 61-66. PubMed Europe PubMed PMC EPMC

2003

[YEAR:6-6-2003]Bernstein,N.K., Cherney,M.M., Yowell,C.A., Dame,J.B. and James,M.N. Structural insights into the activation of P. vivax plasmepsin J Mol Biol (6-6-2003) 329, 505-524. PubMed Europe PubMed DOI S
Martins,T.M., Novo,C., do Rosario,V.E. and Domingos,A. Aspartic proteases from Plasmodium chabaudi: a rodent model for human malaria Acta Trop (2003) 89, 1-12. PubMed Europe PubMed DOI

2001

[YEAR:19-10-2001]Brinkworth,R.I., Prociv,P., Loukas,A. and Brindley,P.J. Hemoglobin-degrading, aspartic proteases of blood-feeding parasites: substrate specificity revealed by homology models J Biol Chem (19-10-2001) 276, 38844-38851. PubMed Europe PubMed DOI I
Coombs,G.H., Goldberg,D.E., Klemba,M., Berry,C., Kay,J. and Mottram,J.C. Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets Trends Parasitol (2001) 17, 532-537. PubMed Europe PubMed DOI
Jiang,S.P., Prigge,S.T., Wei,L., Gao,Y.E., Hudson,T.H., Gerena,L., Dame,J.B. and Kyle,D.E. New class of small nonpeptidyl compounds blocks Plasmodium falciparum development in vitro by inhibiting plasmepsins Antimicrobial Agents Chemother (2001) 45, 2577-2584. PubMed Europe PubMed DOI PMC EPMC

1999

[YEAR:10-12-1999]Humphreys,M.J., Moon,R.P., Klinder,A., Fowler,S.D., Rupp,K., Bur,D., Ridley,R.G. and Berry,C. The aspartic proteinase from the rodent parasite Plasmodium berghei as a potential model for plasmepsins from the human malaria parasite, Plasmodium falciparum FEBS Lett (10-12-1999) 463, 43-48. PubMed Europe PubMed DOI

1997

Westling,J., Yowell,C.A., Majer,P., Erickson,J.W., Dame,J.B. and Dunn,B.M. Plasmodium falciparum, P. vivax, and P. malariae: a comparison of the active site properties of plasmepsins cloned and expressed from three different species of the malaria parasite Exp Parasitol (1997) 87, 185-193. PubMed Europe PubMed DOI