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Literature for peptidase A01.010: cathepsin E

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, T Target, P Specificity, K Knockout, E Expression, V Review, R Splicing, I Inhibitor, L Localization, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Alzoubi,L., Hamzat,Y., Alqudah,A. and Aljabali,A.A.A.
    The Cathepsin Family in Disease: From Molecular Mechanisms to Therapeutic Applications
    Curr Neuropharmacol (2025) PubMed  Europe PubMed DOI
    2. 2024
  2. Deng,T., Lu,X., Jia,X., Du,J., Wang,L., Cao,B., Yang,M., Yin,Y. and Liu,F.
    Cathepsins and cancer risk: a Mendelian randomization study
    Front Endocrinol (Lausanne) (2024) 15, 1428433-1428433. PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2022
  3. Wu,Y., Zhou,W., Yang,Z., Li,J. and Jin,Y.
    miR-185-5p Represses Cells Growth and Metastasis of Osteosarcoma via Targeting Cathepsin E
    Int J Toxicol (2022) 41, 115-125. PubMed  Europe PubMed DOI
    4. 2021
  4. Zhu,Z., Wang,Q., Chen,X., Wang,Q., Yan,C., Zhao,X., Zhao,W. and Zhu,W.H.
    An Enzyme-Activatable Aggregation-Induced-Emission Probe: Intraoperative Pathological Fluorescent Diagnosis of Pancreatic Cancer via Specific Cathepsin E
    Adv Mater (2021) , e2107444-e2107444. PubMed  Europe PubMed DOI
    5. 2020
  5. Hou,J., Li,R., Qiao,S., Chen,X.X., Xing,G. and Zhang,G.
    The Glycoprotein 5 is cleaved by cathepsin E during porcine reproductive and respiratory virus membrane fusion
    J Virol (2020) PubMed  Europe PubMed DOI
  6. Kim,J.W., Cho,J.Y., Kim,J., Kim,D.G., Nam,B.H., Kim,Y.O., An,C.M., Kim,B.S., Park,J.Y. and Kong,H.J.
    First report of cathepsin E in a teleost (Korean rose bitterling, Rhodeus uyekii): molecular characterisation and tissue distribution
    Dev Comp Immunol (2020) , 103607-103607. PubMed  Europe PubMed DOI
  7. Stotz,S., Bleher,D., Kalbacher,H. and Maurer,A.
    Grassystatin-derived peptides selectively inhibit cathepsin E and have low affinity to cathepsin D
    Biochem Biophys Res Commun (2020) 527, 238-241. PubMed  Europe PubMed DOI  I
    8. 2019
  8. Pontious,C., Kaul,S., Hong,M., Hart,P.A., Krishna,S.G., Lara,L.F., Conwell,D.L. and Cruz-Monserrate,Z.
    Cathepsin E expression and activity: role in the detection and treatment of pancreatic cancer
    Pancreatology (2019) 19, 951-956. PubMed  Europe PubMed DOI  L
    9. 2018
  9. Bozic,J., Stoka,V. and Dolenc,I.
    Glucosamine prevents polarization of cytotoxic granules in NK-92 cells by disturbing FOXO1/ERK/paxillin phosphorylation
    PLoS ONE (2018) 13, e0200757-e0200757. PubMed  Europe PubMed DOI  PMC  EPMC
    10. 2017
  10. Al-Awadhi,F.H., Law,B.K., Paul,V.J. and Luesch,H.
    Grassystatins D-F, potent aspartic protease inhibitors from marine cyanobacteria as potential antimetastatic agents targeting invasive breast cancer
    J Nat Prod (2017) 80, 2969-2986. PubMed  Europe PubMed DOI  I
  11. Harada,Y., Takayama,F., Tanabe,K., Ni,J., Hayashi,Y., Yamamoto,K., Wu,Z. and Nakanishi,H.
    Overexpression of cathepsin E interferes with neuronal differentiation of P19 embryonal teratocarcinoma cells by degradation of N-cadherin
    Cell Mol Neurobiol (2017) 37, 437-443. PubMed  Europe PubMed DOI
  12. Ivry,S.L., Sharib,J.M., Dominguez,D.A., Roy,N., Hatcher,S.E., Yip-Schneider,M.T., Schmidt,C.M., Brand,R.E., Park,W.G., Hebrok,M., Kim,G.E., O'Donoghue,A.J., Kirkwood,K.S. and Craik,C.S.
    Global protease activity profiling provides differential diagnosis of pancreatic cysts
    Clin Cancer Res (2017) 23, 4865-4874. PubMed  Europe PubMed DOI
    13. 2016
  13. Al-Awadhi,F.H., Ratnayake,R., Paul,V.J. and Luesch,H.
    Tasiamide F, a potent inhibitor of cathepsins D and E from a marine cyanobacterium
    Bioorg Med Chem (2016) 24, 3276-3282. PubMed  Europe PubMed DOI  I
  14. Cao,W.J., Li,M.H., Li,J.X., Xu,X., Ren,S.X., Rajbanshi,B. and Xu,J.F.
    High expression of cathepsin E is associated with the severity of airflow limitation in patients with COPD
    COPD (2016) 13, 160-166. PubMed  Europe PubMed DOI
  15. Nagasawa,T., Sano,K., Kawaguchi,M., Kobayashi,K., Yasumasu,S. and Inokuchi,T.
    Purification and molecular cloning of aspartic proteinases from the stomach of adult Japanese fire belly newts, Cynops pyrrhogaster
    J Biochem (2016) 159, 449-460. PubMed  Europe PubMed DOI
  16. O'Donoghue,A.J., Ivry,S.L., Chaudhury,C., Hostetter,D.R., Hanahan,D. and Craik,C.S.
    Procathepsin E is highly abundant but minimally active in pancreatic ductal adenocarcinoma tumors
    Biol Chem (2016) 397, 871-881. PubMed  Europe PubMed DOI  I
    17. 2015
  17. Fisher,O.M., Levert-Mignon,A.J., Lord,S.J., Botelho,N.K., Freeman,A.K., Thomas,M.L., Falkenback,D., Wettstein,A., Whiteman,D.C., Bobryshev,Y.V. and Lord,R.V.
    High expression of cathepsin E in tissues but not blood of patients with Barrett's esophagus and adenocarcinoma
    Ann Surg Oncol (2015) 22, 2431-2438. PubMed  Europe PubMed DOI
  18. Ni,J., Wu,Z., Peterts,C., Yamamoto,K., Qing,H. and Nakanishi,H.
    The critical role of proteolytic relay through cathepsins B and E in the phenotypic change of microglia/macrophage
    J Neurosci (2015) 35, 12488-12501. PubMed  Europe PubMed DOI  T
  19. Zeleznik,T.Z., Puizdar,V. and Dolenc,I.
    Expression, purification and auto-activation of cathepsin E from insect cells
    Protein Pept Lett (2015) 22, 525-531. PubMed  Europe PubMed  E
    20. 2014
  20. Kadowaki,T., Kido,M.A., Hatakeyama,J., Okamoto,K., Tsukuba,T. and Yamamoto,K.
    Defective adipose tissue development associated with hepatomegaly in cathepsin E-deficient mice fed a high-fat diet
    Biochem Biophys Res Commun (2014) 446, 212-217. PubMed  Europe PubMed DOI  K
  21. Li,H., Li,Y., Cui,L., Wang,B., Cui,W., Li,M. and Cheng,Y.
    Monitoring pancreatic carcinogenesis by the molecular imaging of cathepsin E in vivo using confocal laser endomicroscopy
    PLoS ONE (2014) 9, e106566-e106566. PubMed  Europe PubMed DOI  PMC  EPMC  L
  22. Lutz,D., Wolters-Eisfeld,G., Schachner,M. and Kleene,R.
    Cathepsin E generates a sumoylated intracellular fragment of the cell adhesion molecule L1 to promote neuronal and Schwann cell migration as well as myelination
    J Neurochem (2014) 128, 713-724. PubMed  Europe PubMed DOI
  23. Zhang,X., Shan,P., Homer,R., Zhang,Y., Petrache,I., Mannam,P. and Lee,P.J.
    Cathepsin E promotes pulmonary emphysema via mitochondrial fission
    Am J Pathol (2014) 184, 2730-2741. PubMed  Europe PubMed DOI
    24. 2013
  24. Abd-Elgaliel,W.R., Cruz-Monserrate,Z., Wang,H., Logsdon,C.D. and Tung,C.H.
    Pancreatic cancer-associated cathepsin E as a drug activator
    J Control Release (2013) 167, 221-227. PubMed  Europe PubMed DOI
  25. Keliher,E.J., Reiner,T., Earley,S., Klubnick,J., Tassa,C., Lee,A.J., Ramaswamy,S., Bardeesy,N., Hanahan,D., DePinho,R.A., Castro,C.M. and Weissleder,R.
    Targeting cathepsin E in pancreatic cancer by a small molecule allows in vivo detection
    Neoplasia (2013) 15, 684-693. PubMed  Europe PubMed DOI  I
  26. Konno-Shimizu,M., Yamamichi,N., Inada,K., Kageyama-Yahara,N., Shiogama,K., Takahashi,Y., Asada-Hirayama,I., Yamamichi-Nishina,M., Nakayama,C., Ono,S., Kodashima,S., Fujishiro,M., Tsutsumi,Y., Ichinose,M. and Koike,K.
    Cathepsin E is a marker of gastric differentiation and signet-ring cell carcinoma of stomach: a novel suggestion on gastric tumorigenesis
    PLoS ONE (2013) 8, e56766-e56766. PubMed  Europe PubMed DOI  PMC  EPMC
  27. Tsukuba,T., Yanagawa,M., Kadowaki,T., Takii,R., Okamoto,Y., Sakai,E., Okamoto,K. and Yamamoto,K.
    Cathepsin E deficiency impairs autophagic proteolysis in macrophages
    PLoS ONE (2013) 8, e82415-e82415. PubMed  Europe PubMed DOI  PMC  EPMC  K
    28. 2012
  28. Andoh,T., Yoshida,T., Lee,J.B. and Kuraishi,Y.
    Cathepsin E induces itch-related response through the production of endothelin-1 in mice
    Eur J Pharmacol (2012) 686, 16-21. PubMed  Europe PubMed DOI
  29. Cruz-Monserrate,Z., Abd-Elgaliel,W.R., Grote,T., Deng,D., Ji,B., Arumugam,T., Wang,H., Tung,C.H. and Logsdon,C.D.
    Detection of pancreatic cancer tumours and precursor lesions by cathepsin E activity in mouse models
    Gut (2012) 61, 1315-1322. PubMed  Europe PubMed DOI
  30. Kitamura,K., Komatsu,M., Biyani,M., Futakami,M., Kawakubo,T., Yamamoto,K. and Nishigaki,K.
    Proven in vitro evolution of protease cathepsin E-inhibitors and -activators at pH 4.5 using a paired peptide method
    J Pept Sci (2012) 18, 711-719. PubMed  Europe PubMed DOI  I
  31. Komatsu,M., Biyani,M., Ghimire Gautam,S. and Nishigaki,K.
    Peptide-modulated activity enhancement of acidic protease cathepsin E at neutral pH
    Int J Pept (2012) 2012, 316432-316432. PubMed  Europe PubMed DOI  PMC  EPMC
  32. Pilzner,C., Buhling,F., Reinheckel,T., Chwieralski,C., Rathinasamy,A., Lauenstein,H.D., Wex,T., Welte,T., Braun,A. and Groneberg,D.A.
    Allergic airway inflammation in mice deficient for the antigen-processing protease cathepsin E
    Int Arch Allergy Immunol (2012) 159, 367-383. PubMed  Europe PubMed DOI  K
  33. Puizdar,V., Zajc,T., Zerovnik,E., Renko,M., Pieper,U., Eswar,N., Sali,A., Dolenc,I. and Turk,V.
    Biochemical characterization and structural modeling of human cathepsin E variant 2 in comparison to the wild-type protein
    Biol Chem (2012) 393, 177-186. PubMed  Europe PubMed DOI
  34. Tsukuba,T., Okamoto,K. and Yamamoto,K.
    Cathepsin E is critical for proper trafficking of cell surface proteins
    J Oral Biosci (2012) 54, 48-53. DOI  V
  35. Yamamoto,K., Kawakubo,T., Yasukochi,A. and Tsukuba,T.
    Emerging roles of cathepsin E in host defense mechanisms
    Biochim Biophys Acta (2012) 1824, 105-112. PubMed  Europe PubMed DOI  V
  36. Yang,S., Zhang,W., Ding,N., Lo,J., Liu,Y., Clare-Salzler,M.J., Luesch,H. and Li,Y.
    Total synthesis of grassystatin A, a probe for cathepsin E function
    Bioorg Med Chem (2012) 20, 4774-4780. PubMed  Europe PubMed DOI  I
  37. Zaidi,N. and Kalbacher,H.
    Cathepsin E
    [ISSN:978-0-12-407744-7] (2012) 3, 42-49. DOI
    38. 2011
  38. Abd-Elgaliel,W.R., Cruz-Monserrate,Z., Logsdon,C.D. and Tung,C.H.
    Molecular imaging of cathepsin E-positive tumors in mice using a novel protease-activatable fluorescent probe
    Mol Biosyst (2011) 7, 3207-3213. PubMed  Europe PubMed DOI  L
  39. Biyani,M., Futakami,M., Kitamura,K., Kawakubo,T., Suzuki,M., Yamamoto,K. and Nishigaki,K.
    In vitro selection of cathepsin E-activity-enhancing peptide aptamers at neutral pH
    Int J Pept (2011) 2011, 834525-834525. PubMed  Europe PubMed DOI  PMC  EPMC  I
  40. Chlabicz,M., Gacko,M., Worowska,A. and Lapinski,R.
    Cathepsin E (EC 3.4.23.34) - a review
    Folia Histochem Cytobiol (2011) 49, 547-557. PubMed  Europe PubMed DOI  V
  41. Kawakubo,T., Yasukochi,A., Nakamura,S. and Yamamoto,K.
    Cathepsin E as a potent anticancer protease
    J Oral Biosci (2011) 53, 128-136. DOI  K
  42. Kawakubo,T., Yasukochi,A., Okamoto,K., Okamoto,Y., Nakamura,S. and Yamamoto,K.
    The role of cathepsin E in terminal differentiation of keratinocytes
    Biol Chem (2011) 392, 571-585. PubMed  Europe PubMed DOI  K
  43. Tulone,C., Sponaas,A.M., Raiber,E.A., Tabor,A.B., Langhorne,J. and Chain,B.M.
    Differential requirement for cathepsin D for processing of the full length and C-terminal fragment of the malaria antigen MSP1
    PLoS ONE (2011) 6, e24886-e24886. PubMed  Europe PubMed DOI  PMC  EPMC
    44. 2010
  44. Abd-Elgaliel,W.R. and Tung,C.H.
    Selective detection of cathepsin E proteolytic activity
    Biochim Biophys Acta (2010) 1800, 1002-1008. PubMed  Europe PubMed DOI  P
  45. Yasukochi,A., Kawakubo,T., Nakamura,S. and Yamamoto,K.
    Cathepsin E enhances anticancer activity of doxorubicin on human prostate cancer cells showing resistance to TRAIL-mediated apoptosis
    Biol Chem (2010) 391, 947-958. PubMed  Europe PubMed DOI
    46. 2009
  46. Kitamura,K., Yoshida,C., Kinoshita,Y., Kadowaki,T., Takahashi,Y., Tayama,T., Kawakubo,T., Naimuddin,M., Salimullah,M., Nemoto,N., Hanada,K., Husimi,Y., Yamamoto,K. and Nishigaki,K.
    Development of systemic in vitro evolution and its application to generation of peptide-aptamer-based inhibitors of cathepsin E
    J Mol Biol (2009) 387, 1186-1198. PubMed  Europe PubMed DOI  I
  47. Kwan,J.C., Eksioglu,E.A., Liu,C., Paul,V.J. and Luesch,H.
    Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation
    J Med Chem (2009) 52, 5732-5747. PubMed  Europe PubMed DOI  PMC  EPMC  I
    48. 2008
  48. Burster,T., Reich,M., Zaidi,N., Voelter,W., Boehm,B.O. and Kalbacher,H.
    Cathepsin E regulates the presentation of tetanus toxin C-fragment in PMA activated primary human B cells
    Biochem Biophys Res Commun (2008) 377, 1299-1303. PubMed  Europe PubMed DOI
  49. Kawakubo,T., Yasukochi,A., Tsukuba,T., Kadowaki,T. and Yamamoto,K.
    Gene expression profiling of mammary glands of cathepsin E-deficient mice compared with wild-type littermates
    Biochimie (2008) 90, 396-404. PubMed  Europe PubMed DOI  K
  50. Misinzo,G.M., Delputte,P.L. and Nauwynck,H.J.
    Involvement of proteases in porcine reproductive and respiratory syndrome virus uncoating upon internalization in primary macrophages
    Vet Res (2008) 39, 55-55. PubMed  Europe PubMed DOI
  51. Ordonez,G.R., Hillier,L.W., Warren,W.C., Grutzner,F., Lopez-Otin,C. and Puente,X.S.
    Loss of genes implicated in gastric function during platypus evolution
    Genome Biol (2008) 9, R81-R81. PubMed  Europe PubMed DOI  PMC  EPMC
  52. Shigematsu,N., Fukuda,T., Yamamoto,T., Nishioku,T., Yamaguchi,T., Himeno,M., Nakayama,K.I., Tsukuba,T., Kadowaki,T., Okamoto,K., Higuchi,S. and Yamamoto,K.
    Association of cathepsin E deficiency with the increased territorial aggressive response of mice
    J Neurochem (2008) 105, 1394-1404. PubMed  Europe PubMed DOI  K
  53. Yoshida,C., Kuniwake,A., Naimuddin,M. and Nishigaki,K.
    Molecular design guided by a local map of sequence space: DNA aptamers that inhibit cathepsin E
    Oligonucleotides (2008) 18, 1-8. PubMed  Europe PubMed DOI  I
  54. Zaidi,N. and Kalbacher,H.
    Cathepsin E: a mini review
    Biochem Biophys Res Commun (2008) 367, 517-522. PubMed  Europe PubMed DOI  V
  55. Zaidi,N., Hermann,C., Herrmann,T. and Kalbacher,H.
    Emerging functional roles of cathepsin E
    Biochem Biophys Res Commun (2008) 377, 327-330. PubMed  Europe PubMed DOI  K  V
    56. 2007
  56. Kakehashi,H., Nishioku,T., Tsukuba,T., Kadowaki,T., Nakamura,S. and Yamamoto,K.
    Differential regulation of the nature and functions of dendritic cells and macrophages by cathepsin E
    J Immunol (2007) 179, 5728-5737. PubMed  Europe PubMed
  57. Kawakubo,T., Okamoto,K., Iwata,J., Shin,M., Okamoto,Y., Yasukochi,A., Nakayama,K.I., Kadowaki,T., Tsukuba,T. and Yamamoto,K.
    Cathepsin E prevents tumor growth and metastasis by catalyzing the proteolytic release of soluble TRAIL from tumor cell surface
    Cancer Res (2007) 67, 10869-10878. PubMed  Europe PubMed DOI  U
  58. Naimuddin,M., Kitamura,K., Kinoshita,Y., Honda-Takahashi,Y., Murakami,M., Ito,M., Yamamoto,K., Hanada,K., Husimi,Y. and Nishigaki,K.
    Selection-by-function: efficient enrichment of cathepsin E inhibitors from a DNA library
    J Mol Recognit (2007) 20, 58-68. PubMed  Europe PubMed DOI  I
  59. Page,J.L., Strom,S.C. and Omiecinski,C.J.
    Regulation of the human cathepsin E gene by the constitutive androstane receptor
    Arch Biochem Biophys (2007) 467, 132-138. PubMed  Europe PubMed DOI
  60. Shin,M., Kadowaki,T., Iwata,J., Kawakubo,T., Yamaguchi,N., Takii,R., Tsukuba,T. and Yamamoto,K.
    Association of cathepsin E with tumor growth arrest through angiogenesis inhibition and enhanced immune responses
    Biol Chem (2007) 388, 1173-1181. PubMed  Europe PubMed DOI
  61. Tulone,C., Tsang,J., Prokopowicz,Z., Grosvenor,N. and Chain,B.
    Natural cathepsin E deficiency in the immune system of C57BL/6J mice
    Immunogenetics (2007) 59, 927-935. PubMed  Europe PubMed DOI
  62. Yanagawa,M., Tsukuba,T., Nishioku,T., Okamoto,Y., Okamoto,K., Takii,R., Terada,Y., Nakayama,K.I., Kadowaki,T. and Yamamoto,K.
    Cathepsin E deficiency induces a novel form of lysosomal storage disorder showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH in macrophages
    J Biol Chem (2007) 282, 1851-1862. PubMed  Europe PubMed DOI  K
  63. Zaidi,N., Herrmann,T., Baechle,D., Schleicher,S., Gogel,J., Driessen,C., Voelter,W. and Kalbacher,H.
    A new approach for distinguishing cathepsin E and D activity in antigen-processing organelles
    FEBS J (2007) 274, 3138-3149. PubMed  Europe PubMed DOI  A
  64. Zaidi,N., Herrmann,T., Voelter,W. and Kalbacher,H.
    Recombinant cathepsin E has no proteolytic activity at neutral pH
    Biochem Biophys Res Commun (2007) 360, 51-55. PubMed  Europe PubMed DOI
    65. 2006
  65. Busquets,L., Guillen,H., DeFord,M.E., Suckow,M.A., Navari,R.M., Castellino,F.J. and Prorok,M.
    Cathepsin E is a specific marker of dysplasia in APC mouse intestine
    Tumour Biol (2006) 27, 36-42. PubMed  Europe PubMed DOI
  66. Narita,Y., Oda,S. and Kageyama,T.
    Rodent monophyly deduced from the unique gastric proteinase constitution and molecular phylogenetic analyses using pepsinogen-C cDNA sequences
    Comp Biochem Physiol Part D Genomics Proteomics (2006) 1, 273-282. PubMed  Europe PubMed DOI
  67. Tsukuba,T., Ikeda,S., Okamoto,K., Yasuda,Y., Sakai,E., Kadowaki,T., Sakai,H. and Yamamoto,K.
    Characterization of rat cathepsin E and mutants with changed active-site residues and lacking propeptides and N-glycosylation, expressed in human embryonic kidney 293T cells
    FEBS J (2006) 273, 219-229. PubMed  Europe PubMed DOI
  68. Tsukuba,T., Yamamoto,S., Yanagawa,M., Okamoto,K., Okamoto,Y., Nakayama,K.I., Kadowaki,T. and Yamamoto,K.
    Cathepsin E-deficient mice show increased susceptibility to bacterial infection associated with the decreased expression of multiple cell surface toll-like receptors
    J Biochem (2006) 140, 57-66. PubMed  Europe PubMed DOI  K
  69. [YEAR:21-9-2006]Zhou,W., Scott,S.A., Shelton,S.B. and Crutcher,K.A.
    Cathepsin D-mediated proteolysis of apolipoprotein E: possible role in Alzheimer's disease
    Neuroscience (21-9-2006) 143, 689-701. PubMed  Europe PubMed DOI
    70. 2005
  70. [YEAR:15-2-2005]Chain,B.M., Free,P., Medd,P., Swetman,C., Tabor,A.B. and Terrazzini,N.
    The expression and function of cathepsin E in dendritic cells
    J Immunol (15-2-2005) 174, 1791-1800. PubMed  Europe PubMed
  71. [YEAR:27-5-2005]Chou,K.C.
    Modeling the tertiary structure of human cathepsin-E
    Biochem Biophys Res Commun (27-5-2005) 331, 56-60. PubMed  Europe PubMed DOI  S
  72. [YEAR:1-5-2005]Henningsson,F., Yamamoto,K., Saftig,P., Reinheckel,T., Peters,C., Knight,S.D. and Pejler,G.
    A role for cathepsin E in the processing of mast-cell carboxypeptidase A
    J Cell Sci (1-5-2005) 118, 2035-2042. PubMed  Europe PubMed DOI
  73. Yasuda,Y., Kohmura,K., Kadowaki,T., Tsukuba,T. and Yamamoto,K.
    A new selective substrate for cathepsin E based on the cleavage site sequence of alpha2-macroglobulin
    Biol Chem (2005) 386, 299-305. PubMed  Europe PubMed DOI
  74. Yasuda,Y., Tsukuba,T., Okamoto,K., Kadowaki,T. and Yamamoto,K.
    The role of the cathepsin E propeptide in correct folding, maturation and sorting to the endosome
    J Biochem (2005) 138, 621-630. PubMed  Europe PubMed DOI
    75. 2004
  75. Cappiello,M.G., Wu,Z., Scott,B.B., McGeehan,G.M. and Harrison,R.K.
    Purification and characterization of recombinant human cathepsin E expressed in human kidney cell line 293
    Protein Expr Purif (2004) 37, 53-60. PubMed  Europe PubMed DOI  E
  76. Igarashi,S., Takizawa,T., Takizawa,T., Yasuda,Y., Uchiwa,H., Hayashi,S., Brysk,H., Robinson,J.M., Yamamoto,K., Brysk,M.M. and Horikoshi,T.
    Cathepsin D, but not cathepsin E, degrades desmosomes during epidermal desquamation
    Br J Dermatol (2004) 151, 355-361. PubMed  Europe PubMed DOI
  77. Kay,J. and Tatnell,P.J.
    Cathepsin E
    [ISSN:0-12-079610-4] (2004) 2, 33-38.  V
  78. [YEAR:17-9-2004]Ostermann,N., Gerhartz,B., Worpenberg,S., Trappe,J. and Eder,J.
    Crystal structure of an activation intermediate of cathepsin E
    J Mol Biol (17-9-2004) 342, 889-899. PubMed  Europe PubMed DOI  S
  79. [YEAR:1-5-2004]Yee,C.S., Yao,Y., Li,P., Klemsz,M.J., Blum,J.S. and Chang,C.H.
    Cathepsin E: a novel target for regulation by class II transactivator
    J Immunol (1-5-2004) 172, 5528-5534. PubMed  Europe PubMed
    80. 2003
  80. Ikuzawa,M., Yasumasu,S., Inokuchi,T., Kobayashi,K., Nomura,K. and Iuchi,I.
    Differential expression of two cathepsin Es during metamorphosis-associated remodeling of the larval to adult type epithelium in Xenopus stomach
    J Biochem (2003) 134, 385-394. PubMed  Europe PubMed DOI
  81. Inokuchi,T., Ikuzawa,M., Mineta,T., Yasumasu,S. and Kobayashi,K.
    Molecular cloning of preprocathepsin E cDNA from the stomach of bullfrog Rana catesbeiana
    Comp Biochem Physiol B Biochem Mol Biol (2003) 135, 647-655. PubMed  Europe PubMed DOI
  82. Shibata,M., Sakai,H., Sakai,E., Okamoto,K., Nishishita,K., Yasuda,Y., Kato,Y. and Yamamoto,K.
    Disruption of structural and functional integrity of alpha2-macroglobulin by cathepsin E
    Eur J Biochem (2003) 270, 1189-1198. PubMed  Europe PubMed DOI
  83. [YEAR:27-1-2003]Tatnell,P.J., Cook,M. and Kay,J.
    An alternatively spliced variant of cathepsin E in human gastric adenocarcinoma cells
    Biochim Biophys Acta (27-1-2003) 1625, 203-206. PubMed  Europe PubMed DOI  R
  84. Tsukuba,T., Okamoto,K., Okamoto,Y., Yanagawa,M., Kohmura,K., Yasuda,Y., Uchi,H., Nakahara,T., Furue,M., Nakayama,K., Kadowaki,T., Yamamoto,K. and Nakayama,K.I.
    Association of cathepsin E deficiency with development of atopic dermatitis
    J Biochem (2003) 134, 893-902. PubMed  Europe PubMed DOI  K
    85. 2002
  85. Athauda,S.B. and Takahashi,K.
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