Literature for peptidase C01.046: falcipain-2

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates Pharma

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2011

Hansen,G., Heitmann,A., Witt,T., Li,H., Jiang,H., Shen,X., Heussler,V.T., Rennenberg,A. and Hilgenfeld,R.
Structural basis for the regulation of cysteine-protease activity by a new class of protease inhibitors in Plasmodium
Structure19, 919-929. PubMed Europe PubMed DOI S

2009

Kerr,I.D., Lee,J.H., Pandey,K.C., Harrison,A., Sajid,M., Rosenthal,P.J. and Brinen,L.S.
Structures of falcipain-2 and falcipain-3 bound to small molecule inhibitors: implications for substrate specificity
J Med Chem52, 852-857. PubMed Europe PubMed DOI S I

2006

[YEAR:1-8-2006]Wang,S.X., Pandey,K.C., Somoza,J.R., Sijwali,P.S., Kortemme,T., Brinen,L.S., Fletterick,R.J., Rosenthal,P.J. and McKerrow,J.H.
Structural basis for unique mechanisms of folding and hemoglobin binding by a malarial protease
Proc Natl Acad Sci U S A103, 11503-11508. PubMed Europe PubMed DOI S