Literature for peptidase C12.001: ubiquitinyl hydrolase-L1

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

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    2025
  1. Yang,J.J., Liu,H.J., Wang,Y.X., Wang,L.P., Gu,J.J., Gao,J.Y., Ren,K.Q. and Min,L.F.
    Oxidative Stress and Epithelial-Mesenchymal Transition: The Impact of Ubiquitin C-terminal Hydrolase L1 in Cigarette Smoke-Induced COPD
    Lung203, 36-36. PubMed  Europe PubMed DOI  K
  2. 2024
  3. Antony,R., Aby,K., Montgomery,M. and Li,Y.
    Skeletal Muscle UCHL1 Negatively Regulates Muscle Development and Recovery after Muscle Injury
    Int J Mol Sci25, PubMed  Europe PubMed DOI  K
  4. 2023
  5. Bednash,J.S., Johns,F., Farkas,D., Elhance,A., Adair,J., Cress,K., Yount,J.S., Kenney,A.D., Londino,J.D. and Mallampalli,R.K.
    Inhibiting the Deubiquitinase UCHL1 Reduces SARS-CoV-2 Viral Uptake by ACE2
    Am J Respir Cell Mol Biol68, 566-576. PubMed  Europe PubMed DOI  K
  6. 2022
  7. Huynh,T.K.T., Mai,T.T.T., Huynh,M.A., Yoshida,H., Yamaguchi,M. and Dang,T.T.P.
    Crucial Roles of Ubiquitin Carboxy-Terminal Hydrolase L1 in Motor Neuronal Health by Drosophila Model
    Antioxid Redox Signal37, 257-273. PubMed  Europe PubMed DOI  K
  8. 2021
  9. Mitra,S., Epshtein,Y., Sammani,S., Quijada,H., Chen,W., Bandela,M., Desai,A.A., Garcia,J.G.N. and Jacobson,J.R.
    UCHL1, a Deubiquitinating Enzyme, Regulates Lung Endothelial Cell Permeability In Vitro and In Vivo
    Am J Physiol Lung Cell Mol Physiol PubMed  Europe PubMed DOI  K  I
  10. 2020
  11. Lei,Q., Yi,T., Li,H., Yan,Z., Lv,Z., Li,G. and Wang,Y.
    Ubiquitin C-terminal hydrolase L1 (UCHL1) regulates post-myocardial infarction cardiac fibrosis through glucose-regulated protein of 78 kDa (GRP78)
    Sci Rep10, 10604-10604. PubMed  Europe PubMed DOI  K
  12. 2018
  13. Boisvert,N.C., Holterman,C.E., Thibodeau,J.F., Nasrallah,R., Kamto,E., Comin,C.H., Costa,L.D.F., Carter,A., Hebert,R.L., Gutsol,A., Cron,G.O., Lacoste,B., Gray,D.A. and Kennedy,C.R.
    Hyperfiltration in ubiquitin C-terminal hydrolase L1-deleted mice
    Clin Sci (Lond)132, 1453-1470. PubMed  Europe PubMed DOI  K
  14. 2016
  15. Genc,B., Jara,J.H., Schultz,M.C., Manuel,M., Stanford,M.J., Gautam,M., Klessner,J.L., Sekerkova,G., Heller,D.B., Cox,G.A., Heckman,C.J., DiDonato,C.J. and Ozdinler,P.H.
    Absence of UCHL 1 function leads to selective motor neuropathy
    Ann Clin Transl Neurol3, 331-345. PubMed  Europe PubMed DOI  K  M
  16. 2014
  17. Coulombe,J., Gamage,P., Gray,M.T., Zhang,M., Tang,M.Y., Woulfe,J., Saffrey,M.J. and Gray,D.A.
    Loss of UCHL1 promotes age-related degenerative changes in the enteric nervous system
    Front Aging Neurosci6, 129-129. PubMed  Europe PubMed DOI  K  M
  18. Read,N.C., Gutsol,A., Holterman,C.E., Carter,A., Coulombe,J., Gray,D.A. and Kennedy,C.R.
    Ubiquitin C-terminal hydrolase L1 deletion ameliorates glomerular injury in mice with ACTN4-associated focal segmental glomerulosclerosis
    Biochim Biophys Acta1842, 1028-1040. PubMed  Europe PubMed DOI  K
  19. 2012
  20. Pfeffer,M., Plenzig,S., Gispert,S., Wada,K., Korf,H.W. and Von Gall,C.
    Disturbed sleep/wake rhythms and neuronal cell loss in lateral hypothalamus and retina of mice with a spontaneous deletion in the ubiquitin carboxyl-terminal hydrolase L1 gene
    Neurobiol Aging33, 393-403. PubMed  Europe PubMed DOI  K
  21. 2010
  22. Basseres,E., Coppotelli,G., Pfirrmann,T., Andersen,J.B., Masucci,M. and Frisan,T.
    The ubiquitin C-terminal hydrolase UCH-L1 promotes bacterial invasion by altering the dynamics of the actin cytoskeleton
    Cell Microbiol12, 1622-1633. PubMed  Europe PubMed DOI  K
  23. Chen,F., Sugiura,Y., Myers,K.G., Liu,Y. and Lin,W.
    Ubiquitin carboxyl-terminal hydrolase L1 is required for maintaining the structure and function of the neuromuscular junction
    Proc Natl Acad Sci U S A107, 1636-1641. PubMed  Europe PubMed DOI  K
  24. 2009
  25. Rolen,U., Freda,E., Xie,J., Pfirrmann,T., Frisan,T. and Masucci,M.G.
    The ubiquitin C-terminal hydrolase UCH-L1 regulates B-cell proliferation and integrin activation
    J Cell Mol Med13, 1666-1678. PubMed  Europe PubMed DOI  K
  26. 2008
  27. Shim,S., Kwon,Y.B., Yoshikawa,Y. and Kwon,J.
    Ubiquitin C-terminal hydrolase L1 deficiency decreases bone mineralization
    J Vet Med Sci70, 649-651. PubMed  Europe PubMed DOI  K
  28. 2007
  29. Kwon,J.
    The new function of two ubiquitin C-terminal hydrolase isozymes as reciprocal modulators of germ cell apoptosis
    Exp Anim56, 71-77. PubMed  Europe PubMed DOI  K
  30. 2006
  31. Kwon,J., Sekiguchi,S., Wang,Y.L., Setsuie,R., Yoshikawa,Y. and Wada,K.
    The region-specific functions of two ubiquitin C-terminal hydrolase isozymes along the epididymis
    Exp Anim55, 35-43. PubMed  Europe PubMed DOI  K
  32. 2001
  33. [YEAR:1-9-2001]Kurihara,L.J., Kikuchi,T., Wada,K. and Tilghman,S.M.
    Loss of Uch-L1 and Uch-L3 leads to neurodegeneration, posterior paralysis and dysphagia
    Hum Mol Genet10, 1963-1970. PubMed  Europe PubMed  K
  34. 2000
  35. [YEAR:15-6-2000]Wang,Y., Saigoh,K., Osaka,H., Yamanishi,T., Suh,J., Kiyosawa,H., Sakai,Y., Wakana,S. and Wada,K.
    YAC/BAC-based physical and transcript mapping around the gracile axonal dystrophy (gad) locus identifies Uchl1, Pmx2b, Atp3a2, and Hip2 genes
    Genomics66, 333-336. PubMed  Europe PubMed DOI  K  M
  36. 1999
  37. Saigoh,K., Wang,Y.L., Suh,J.G., Yamanishi,T., Sakai,Y., Kiyosawa,H., Harada,T., Ichihara,N., Wakana,S., Kikuchi,T. and Wada,K.
    Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice
    Nat Genet23, 47-51. PubMed  Europe PubMed DOI  K