Literature for peptidase S01.191: complement factor D

(References are filtered for relevance to Inhibitor. To remove the filter click here. See explanation.)

2019
1. Karki,R.G., Powers,J., Mainolfi,N., Anderson,K., Belanger,D.B., Liu,D., Ji,N., Jendza,K., Gelin,C.F., Mac Sweeney,A., Solovay,C., Delgado,O., Crowley,M., Liao,S.M., Argikar,U.A., Flohr,S., La Bonte,L.R., Lorthiois,E.L., Vulpetti,A., Brown,A., Long,D., Prentiss,M., Gradoux,N., de Erkenez,A., Cumin,F., Adams,C., Jaffee,B. and Mogi,M.
   Design, synthesis, and preclinical characterization of selective factor D inhibitors targeting the alternative complement pathway
   J Med Chem62, 4656-4668. PubMed  Europe PubMed DOI  I
2018
2. Vulpetti,A., Ostermann,N., Randl,S., Yoon,T., Mac Sweeney,A., Cumin,F., Lorthiois,E., Rudisser,S., Erbel,P. and Maibaum,J.
   Discovery and design of first benzylamine-based ligands binding to an unlocked conformation of the complement factor D
   ACS Med Chem Lett9, 490-495. PubMed  Europe PubMed DOI  I
2017
3. Lorthiois,E., Anderson,K., Vulpetti,A., Rogel,O., Cumin,F., Ostermann,N., Steinbacher,S., Mac Sweeney,A., Delgado,O., Liao,S.M., Randl,S., Rudisser,S., Dussauge,S., Fettis,K., Kieffer,L., de Erkenez,A., Yang,L., Hartwieg,C., Argikar,U.A., La Bonte,L.R., Newton,R., Kansara,V., Flohr,S., Hommel,U., Jaffee,B. and Maibaum,J.
   Discovery of highly potent and selective small-molecule reversible factor D inhibitors demonstrating alternative complement pathway inhibition in vivo
   J Med Chem60, 5717-5735. PubMed  Europe PubMed DOI  I
4. Vulpetti,A., Randl,S., Rudisser,S., Ostermann,N., Erbel,P., Mac Sweeney,A., Zoller,T., Salem,B., Gerhartz,B., Cumin,F., Hommel,U., Dalvit,C., Lorthiois,E. and Maibaum,J.
   Structure-based library design and fragment screening for the identification of reversible complement factor D protease inhibitors
   J Med Chem60, 1946-1958. PubMed  Europe PubMed DOI  I
2016
5. Maibaum,J., Liao,S.M., Vulpetti,A., Ostermann,N., Randl,S., Rudisser,S., Lorthiois,E., Erbel,P., Kinzel,B., Kolb,F.A., Barbieri,S., Wagner,J., Durand,C., Fettis,K., Dussauge,S., Hughes,N., Delgado,O., Hommel,U., Gould,T., Mac Sweeney,A., Gerhartz,B., Cumin,F., Flohr,S., Schubart,A., Jaffee,B., Harrison,R., Risitano,A.M., Eder,J. and Anderson,K.
   Small-molecule factor D inhibitors targeting the alternative complement pathway
   Nat Chem Biol12, 1105-1110. PubMed  Europe PubMed DOI  I
6. Yang,C.Y., Phillips,J.G., Stuckey,J.A., Bai,L., Sun,H., Delproposto,J., Brown,W.C. and Chinnaswamy,K.
   Buried hydrogen bond interactions contribute to the high potency of complement factor D inhibitors
   ACS Med Chem Lett7, 1092-1096. PubMed  Europe PubMed DOI  S  I
1998
7. Cole,L.B., Kilpatrick,J.M., Chu,N. and Babu,Y.S.
   Structure of 3,4-dichloroisocoumarin-inhibited factor D
   Acta Crystallogr D Biol Crystallogr54, 711-717. PubMed  Europe PubMed DOI  S  I
8. [YEAR:9-10-1998]Jing,H., Babu,Y.S., Moore,D., Kilpatrick,J.M., Liu,X.Y., Volanakis,J.E. and Narayana,S.V.
   Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity
   J Mol Biol282, 1061-1081. PubMed  Europe PubMed DOI  S  I
1994
9. Inagi,R., Miyata,T., Oda,O., Maeda,K. and Inoue,K.
   Evaluation of the proteolytic activity of factor D accumulated as an active serine protease in patients with chronic renal failure
   Nephron66, 285-290. PubMed  Europe PubMed  I
1992
10. Kam,C.M., Oglesby,T.J., Pangburn,M.K., Volanakis,J.E. and Powers,J.C.
    Substituted isocoumarins as inhibitors of complement serine proteases
    J Immunol149, 163-168. PubMed  Europe PubMed  I