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Literature for peptidase C03.005: hepatitis A virus-type picornain 3C

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

(References are filtered for relevance to Inhibitor. To remove the filter click here. See explanation.)

    2024
  1. Sureshan,M., Brintha,S. and Jothi,A.
    Identification of Mulberrofuran as a potent inhibitor of hepatitis A virus 3C(pro) and RdRP enzymes through structure-based virtual screening, dynamics simulation, and DFT studies
    Mol Divers28, 1609-1628. PubMed  Europe PubMed DOI  I
    2. 2019
  2. Al-Salahi,R., Anouar,E.H., Marzouk,M. and Abuelizz,H.A.
    Anti-HAV evaluation and molecular docking of newly synthesized 3-benzyl(phenethyl)benzo[g]quinazolines
    Bioorg Med Chem Lett29, 1614-1619. PubMed  Europe PubMed DOI  I
  3. Banerjee,K., Bhat,R., Rao,V.U.B., Nain,A., Rallapalli,K.L., Gangopadhyay,S., Singh,R.P., Banerjee,M. and Jayaram,B.
    Toward development of generic inhibitors against the 3C proteases of picornaviruses
    FEBS J286, 765-787. PubMed  Europe PubMed DOI  I
  4. Kassem,A.F., Batran,R.Z., Abbas,E.M.H., Elseginy,S.A., Shaheen,M.N.F. and Elmahdy,E.M.
    New 4-phenylcoumarin derivatives as potent 3C protease inhibitors: design, synthesis, anti-HAV effect and molecular modeling
    Eur J Med Chem168, 447-460. PubMed  Europe PubMed DOI  I
    5. 2012
  5. Blaum,B.S., Wunsche,W., Benie,A.J., Kusov,Y., Peters,H., Gauss-Muller,V., Peters,T. and Sczakiel,G.
    Functional binding of hexanucleotides to 3C protease of hepatitis A virus
    Nucleic Acids Res40, 3042-3055. PubMed  Europe PubMed DOI  I
    6. 2008
  6. Huitema,C., Zhang,J., Yin,J., James,M.N., Vederas,J.C. and Eltis,L.D.
    Heteroaromatic ester inhibitors of hepatitis A virus 3C proteinase: evaluation of mode of action
    Bioorg Med Chem16, 5761-5777. PubMed  Europe PubMed DOI  T  I
  7. Sperry,J. and Brimble,M.A.
    An efficient enantioselective synthesis of the 3C protease inhibitor (-)-thysanone
    Synlett2008, 1910-1912. DOI  I
    8. 2006
  8. [YEAR:7-7-2006]Yin,J., Cherney,M.M., Bergmann,E.M., Zhang,J., Huitema,C., Pettersson,H., Eltis,L.D., Vederas,J.C. and James,M.N.
    An episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors
    J Mol Biol361, 673-686. PubMed  Europe PubMed DOI  S  I
    9. 2005
  9. [YEAR:14-10-2005]Yin,J., Bergmann,E.M., Cherney,M.M., Lall,M.S., Jain,R.P., Vederas,J.C. and James,M.N.
    Dual modes of modification of hepatitis A virus 3C protease by a serine-derived beta-lactone: selective crystallization and formation of a functional catalytic triad in the active site
    J Mol Biol354, 854-871. PubMed  Europe PubMed DOI  S  I
    10. 2004
  10. Lall,M.S., Jain,R.P. and Vederas,J.C.
    Inhibitors of 3C cysteine proteinases from Picornaviridae
    Curr Top Med Chem4, 1239-1253. PubMed  Europe PubMed DOI  I
    11. 2002
  11. [YEAR:8-3-2002]Lall,M.S., Ramtohul,Y.K., James,M.N. and Vederas,J.C.
    Serine and threonine beta-lactones: a new class of hepatitis a virus 3C cysteine proteinase inhibitors
    J Org Chem67, 1536-1547. PubMed  Europe PubMed DOI  I
  12. [YEAR:17-5-2002]Ramtohul,Y.K., James,M.N. and Vederas,J.C.
    Synthesis and evaluation of keto-glutamine analogues as inhibitors of hepatitis A virus 3C proteinase
    J Org Chem67, 3169-3178. PubMed  Europe PubMed DOI  I
    13. 1999
  13. [YEAR:5-12-1999]Bergmann,E.M., Cherney,M.M., Mckendrick,J., Frormann,S., Luo,C., Malcolm,B.A., Vederas,J.C. and James,M.N.
    Crystal structure of an inhibitor complex of the 3C proteinase from hepatitis A virus (HAV) and implications for the polyprotein processing in HAV
    Virology265, 153-163. PubMed  Europe PubMed DOI  S  I
  14. Huang,Y., Malcolm,B.A. and Vederas,J.C.
    Synthesis and testing of azaglutamine derivatives as inhibitors of hepatitis A virus (HAV) 3C proteinase
    Bioorg Med Chem7, 607-619. PubMed  Europe PubMed DOI  I
    15. 1997
  15. Morris,T.S., Frormann,S., Shechosky,S., Lowe,C., Lall,M.S., Gauss-Muller,V., Purcell,R.H., Emerson,S.U., Vederas,J.C. and Malcolm,B.A.
    In vitro and ex vivo inhibition of hepatitis A virus 3C proteinase by a peptidyl monofluoromethyl ketone
    Bioorg Med Chem5, 797-807. PubMed  Europe PubMed DOI  I
    16. 1995
  16. Malcolm,B.A., Lowe,C., Shechosky,S., McKay,R.T., Yang,C.C., Shah,V.J., Simon,R.J., Vederas,J.C. and Santi,D.V.
    Peptide aldehyde inhibitors of hepatitis A virus 3C proteinase
    Biochemistry34, 8172-8179. PubMed  Europe PubMed DOI  I

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