Literature for peptidase C01.074: CPB peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors Pharma

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    2020
  1. Cianni,L., Rocho,F.D.R., Rosini,F., Bonatto,V., Ribeiro,J.F.R., Lameira,J., Leitao,A., Shamim,A. and Montanari,C.A.
    Optimization strategy of single-digit nanomolar cross-class inhibitors of mammalian and protozoa cysteine proteases
    Bioorg Chem (2020) 101, 104039-104039. PubMed  Europe PubMed DOI  I
  2. Ghosh,S., Verma,A., Kumar,V., Pradhan,D., Selvapandiyan,A., Salotra,P. and Singh,R.
    Genomic and Transcriptomic Analysis for Identification of Genes and Interlinked Pathways Mediating Artemisinin Resistance in Leishmania donovani
    Genes (Basel) (2020) 11 PubMed  Europe PubMed DOI  PMC  EPMC  I
  3. Matos,T.K.B., Batista,P.H.J., Dos Reis Rocho,F., De Vita,D., Pearce,N., Kellam,B., Montanari,C.A. and Leitao,A.
    Synthesis and matched molecular pair analysis of covalent reversible inhibitors of the cysteine protease CPB
    Bioorg Med Chem Lett (2020) 30, 127439-127439. PubMed  Europe PubMed DOI  I
  4. Ribeiro,J.F.R., Cianni,L., Li,C., Warwick,T.G., De Vita,D., Rosini,F., Dos Reis Rocho,F., Martins,F.C.P., Kenny,P.W., Lameira,J., Leitao,A., Emsley,J. and Montanari,C.A.
    Crystal structure of Leishmania mexicana cysteine protease B in complex with a high-affinity azadipeptide nitrile inhibitor
    Bioorg Med Chem (2020) 28, 115743-115743. PubMed  Europe PubMed DOI  I
  5. 2018
  6. De Luca,L., Ferro,S., Buemi,M.R., Monforte,A.M., Gitto,R., Schirmeister,T., Maes,L., Rescifina,A. and Micale,N.
    Discovery of benzimidazole-based Leishmania mexicana cysteine protease CPB2.8DeltaCTE inhibitors as potential therapeutics for leishmaniasis
    Chem Biol Drug Des (2018) 92, 1585-1596. PubMed  Europe PubMed DOI  I
  7. Fey,P., Chartomatsidou,R., Kiefer,W., Mottram,J.C., Kersten,C. and Schirmeister,T.
    New aziridine-based inhibitors of cathepsin L-like cysteine proteases with selectivity for the Leishmania cysteine protease LmCPB2.8
    Eur J Med Chem (2018) 156, 587-597. PubMed  Europe PubMed DOI  I
  8. 2016
  9. Scala,A., Micale,N., Piperno,A., Rescifina,A., Schirmeister,T., Kesselring,J. and Grassi,G.
    Targeting of the Leishmania mexicana cysteine protease CPB2.8DCTE by decorated fused benzo[b] thiophene scaffold
    RSC Adv (2016) 6, 30628-30635. DOI  I
  10. 2015
  11. De Sousa,L.R., Wu,H., Nebo,L., Fernandes,J.B., da Silva,M.F., Kiefer,W., Schirmeister,T. and Vieira,P.C.
    Natural products as inhibitors of recombinant cathepsin L of Leishmania mexicana
    Exp Parasitol (2015) 156, 42-48. PubMed  Europe PubMed DOI  I
  12. Gontijo,V.S., Espuri,P.F., Alves,R.B., de Camargos,L.F., Santos,F.V., de Souza Judice,W.A., Marques,M.J. and Freitas,R.P.
    Leishmanicidal, antiproteolytic, and mutagenic evaluation of alkyltriazoles and alkylphosphocholines
    Eur J Med Chem (2015) 101, 24-33. PubMed  Europe PubMed DOI  I
  13. 2013
  14. Schroder,J., Noack,S., Marhofer,R.J., Mottram,J.C., Coombs,G.H. and Selzer,P.M.
    Identification of semicarbazones, thiosemicarbazones and triazine nitriles as inhibitors of Leishmania mexicana cysteine protease CPB
    PLoS ONE (2013) 8, e77460-e77460. PubMed  Europe PubMed DOI  PMC  EPMC  I
  15. Unciti-Broceta,J.D., Maceira,J., Morales,S., Garcia-Perez,A., Munoz-Torres,M.E. and Garcia-Salcedo,J.A.
    Nicotinamide inhibits the lysosomal cathepsin B-like protease and kills African trypanosomes
    J Biol Chem (2013) 288, 10548-10557. PubMed  Europe PubMed DOI  I
  16. 2010
  17. Steert,K., Berg,M., Mottram,J.C., Westrop,G.D., Coombs,G.H., Cos,P., Maes,L., Joossens,J., Van der Veken,P., Haemers,A. and Augustyns,K.
    alpha-Ketoheterocycles as inhibitors of Leishmania mexicana cysteine protease CPB
    ChemMedChem (2010) 5, 1734-1748. PubMed  Europe PubMed DOI  I
  18. 2009
  19. Caffrey,C.R. and Steverding,D.
    Kinetoplastid papain-like cysteine peptidases
    Mol Biochem Parasitol (2009) 167, 12-19. PubMed  Europe PubMed DOI  I
  20. 2003
  21. Chibale,K. and Musonda,C.C.
    The synthesis of parasitic cysteine protease and trypanothione reductase inhibitors
    Curr Med Chem (2003) 10, 1863-1889. PubMed  Europe PubMed DOI  I
  22. 2002
  23. [YEAR:9-5-2002]St Hilaire,P.M., Alves,L.C., Herrera,F., Renil,M., Sanderson,S.J., Mottram,J.C., Coombs,G.H., Juliano,M.A., Juliano,L., Arevalo,J. and Meldal,M.
    Solid-phase library synthesis, screening, and selection of tight-binding reduced peptide bond inhibitors of a recombinant Leishmania mexicana cysteine protease B
    J Med Chem (9-5-2002) 45, 1971-1982. PubMed  Europe PubMed DOI  I
  24. 2001
  25. Graven,A., St,H.P.M., Sanderson,S.J., Mottram,J.C., Coombs,G.H. and Meldal,M.
    Combinatorial library of peptide isosters based on Diels-Alder reactions: identification of novel inhibitors against a recombinant cysteine protease from Leishmania mexicana
    J Comb Chem (2001) 3, 441-452. PubMed  Europe PubMed DOI  I