Literature for peptidase A22.007: signal peptide peptidase-like protein 2A

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(References are filtered for relevance to Inhibitor. To remove the filter click here. See explanation.)

2019

Velcicky,J., Mathison,C.J.N., Nikulin,V., Pflieger,D., Epple,R., Azimioara,M., Cow,C., Michellys,P.Y., Rigollier,P., Beisner,D.R., Bodendorf,U., Guerini,D., Liu,B., Wen,B., Zaharevitz,S. and Brandl,T.
Discovery of orally active hydroxyethylamine based SPPL2a inhibitors
ACS Med Chem Lett10, 887-892. PubMed Europe PubMed DOI I

2018

Velcicky,J., Bodendorf,U., Rigollier,P., Epple,R., Beisner,D.R., Guerini,D., Smith,P., Liu,B., Feifel,R., Wipfli,P., Aichholz,R., Couttet,P., Dix,I., Widmer,T., Wen,B. and Brandl,T.
Discovery of the first potent, selective, and orally bioavailable signal peptide peptidase-like 2a (SPPL2a) inhibitor displaying pronounced immunomodulatory effects in vivo
J Med Chem61, 865-880. PubMed Europe PubMed DOI I

2017

Zhang,X., Gotte,M., Ibig-Rehm,Y., Schuffenhauer,A., Kamke,M., Beisner,D., Guerini,D., Siebert,D., Bonamy,G.M.C., Gabriel,D. and Bodendorf,U.
Identification of SPPL2a inhibitors by multiparametric analysis of a high-content ultra-high-throughput screen
SLAS Discov22, 1106-1119. PubMed Europe PubMed DOI I