Summary for XT01.003

Summary Substrates Inhibitors

 

Names
MEROPS Name
MEROPS Classification
Activity
Catalytic typeThreonine
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/-Scissile bond-/-/-/- (based on 352 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 40 28 23 17 36 21 39 35
Pro 17 16 7 1 15 19 18 12
Ala 42 28 35 45 62 44 41 24
Val 27 41 39 28 15 30 25 30
Leu 28 24 20 67 10 24 38 24
Ile 18 25 12 23 6 20 16 18
Met 6 6 10 7 10 3 3 9
Phe 13 9 20 19 6 10 8 16
Tyr 18 12 11 23 21 10 5 13
Trp 2 2 2 11 2 0 1 4
Ser 29 17 37 13 26 22 22 32
Thr 12 14 23 9 15 24 17 18
Cys 0 0 0 0 1 0 1 0
Asn 21 17 14 12 22 24 22 22
Gln 10 12 13 7 15 16 13 13
Asp 9 19 9 15 17 36 20 25
Glu 17 21 17 15 22 23 19 14
Lys 22 40 32 17 23 15 18 16
Arg 8 10 18 14 19 5 14 13
His 7 9 9 9 9 5 8 8