$VAR1 = undef;

Summary for peptidase T02.002: isoaspartyl dipeptidase (threonine type)

Names
MEROPS Name	isoaspartyl dipeptidase (threonine type)
Other names	asparaginase, asparaginase precursor, ASRGL1 g.p. (Homo sapiens), beta-aspartyl peptidase (eukaryote), beta-aspartyldipeptidase, EcAIII (Escherichia coli), hASNase3, human asparaginase 3, isoaspartyl aminopeptidase, isoaspartyl peptidase, Mername-AA125 peptidase, plant-type asparaginase, ybiK g.p. (Escherichia coli)

Domain architecture

MEROPS Classification
Classification	Clan PB >> Subclan PB(T) >> Family T2 >> Subfamily (none) >> T02.002
Holotype	isoaspartyl dipeptidase (threonine type) (Escherichia coli), Uniprot accession P37595 (peptidase unit: 179-321), MERNUM MER0003338
History	Identifier created: MEROPS 3.4 (5 November 1999)

Activity
Catalytic type	Threonine
NC-IUBMB	Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.19 (Omega peptidases) >> Peptidase 3.4.19.5;
Enzymology	BRENDA database
Other databases	TREEFAM	http://www.treefam.org/family/TF323960
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/-/-/D-/-/-/- (based on 17 cleavages)

Specificity matrix

Amino acid	P1	P1'	P2'
Gly	0	4	1
Pro	0	0	0
Ala	0	2	2
Val	0	1	1
Leu	0	3	0
Ile	0	1	0
Met	0	1	0
Phe	0	1	0
Tyr	0	0	0
Trp	0	0	0
Ser	0	1	0
Thr	0	1	0
Cys	0	0	0
Asn	0	0	0
Gln	0	0	0
Asp	17	0	0
Glu	0	0	0
Lys	0	1	0
Arg	0	0	0
His	0	1	0

Human genetics
Gene symbol	Locus	Megabases	Ensembl	Entrez gene	Gene Cards	OMIM
ASRGL1	11q12.3		ENSG00000162174	80150	ASRGL1