Summary for peptidase homologue T01.984: proteasome subunit beta 2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Pharma

 

Names
MEROPS Nameproteasome subunit beta 2
Other namesproteasome subunit C7 (Homo sapiens), C11 g.p. (Saccharomyces cerevisiae), PRE1 g.p. (Saccharomyces cerevisiae), PSMB2 g.p. (Homo sapiens)
Domain architecture
MEROPS Classification
Classification Clan PB >> Subclan PB(T) >> Family T1 >> Subfamily A >> T01.984
Holotypeproteasome subunit beta 2 (Homo sapiens), Uniprot accession P49721 (peptidase unit: 5-147), MERNUM MER0002676
History Identifier created: MEROPS 3.02 (25 June 1998)
Activity
Catalytic typeNon-peptidase homologue
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.25 (Threonine-type endopeptidases) >> Peptidase 3.4.25.1
EnzymologyBRENDA database
Activity statushuman: inactive
mouse: inactive
PhysiologyOne of the non-peptidase subunits of the 20 S proteasome, but homolgous with the catalytically-active beta subunits.
Pathways KEGGProteasome
Other databases TREEFAMhttp://www.treefam.org/family/TF106219
PANTHERhttp://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR11599:SF6
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
PSMB2 1p34.2 ENSG00000126067 5690 PSMB2 602175
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Psmb2 4:D2.2 ENSMUSG00000028837 26445 MGI:1347045