$VAR1 = undef;
Summary for peptidase S28.003: thymus-specific serine peptidase
| Names | |
|---|---|
| MEROPS Name | thymus-specific serine peptidase |
| Other names | Mername-AA266 peptidase, TSSP, PRSS16 g.p. (Homo sapiens) |
| Domain architecture |
|---|
| MEROPS Classification | |
|---|---|
| Classification | Clan SC >> Subclan (none) >> Family S28 >> Subfamily (none) >> S28.003 |
| Holotype | thymus-specific serine peptidase (Mus musculus), Uniprot accession Q9QXE5 (peptidase unit: 54-509), MERNUM MER0006066 |
| History | Identifier created: MEROPS 3.4 (5 November 1999) |
| Activity | |||
|---|---|---|---|
| Catalytic type | Serine | ||
| NC-IUBMB | Not yet included in IUBMB recommendations. | ||
| Activity status | human: putative mouse: putative | ||
| Physiology | Thymus-specific serine peptidase is a serine peptidase that is reported to be expressed exclusively in cortical thymic epithelial cells of the thymus (Cheunsuk et al., 2005). | ||
| Knockout | Mice deficient in thymus-specific serine peptidase develop normally, are fertile, and show normal thymic morphology, cellularity, and anatomy (Cheunsuk et al., 2005). | ||
| Other databases | TREEFAM | http://www.treefam.org/family/TF314855 | |
| Human genetics | ||||||
|---|---|---|---|---|---|---|
| Gene symbol | Locus | Megabases | Ensembl | Entrez gene | Gene Cards | OMIM |
| PRSS16 | 6p21.31-p22.2 | ENSG00000112812 | 10279 | PRSS16 | 607169 | |
| Mouse genetics | ||||||
| Gene symbol | Position | Megabases | Ensembl | Entrez gene | MGI | |
| Prss16 | 13 | ENSMUSG00000006179 | 54373 | MGI:1859181 | ||
