$VAR1 = undef;

Summary for peptidase homologue S09.973: dipeptidylpeptidase homologue DPP6

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Pharma

 

Names
MEROPS Namedipeptidylpeptidase homologue DPP6
Other namesdipeptidyl-peptidase-like protein-6, DPP6 g.p (Homo sapiens), DPP X, neural membrane CD26 peptidase-like protein
Domain architecture
MEROPS Classification
Classification Clan SC >> Subclan (none) >> Family S9 >> Subfamily X >> S09.973
Holotypedipeptidylpeptidase homologue DPP6 (Homo sapiens), Uniprot accession P42658 (peptidase unit: 586-849), MERNUM MER0000403
History Identifier created: MEROPS 5.00 (20 April 2000)
Activity
Catalytic typeNon-peptidase homologue
NC-IUBMBNot yet included in IUBMB recommendations.
Activity statushuman: inactive
mouse: inactive
KnockoutThe mouse rump white (Rw) mutation causes a pigmentation defect in heterozygotes and embryonic lethality in homozygotes. The recessive lethality is probably due to the disruption of the gene encoding dipeptidylpeptidase-like protein DPP6 (Hough et al., 1998).
Other databases TREEFAMhttp://www.treefam.org/family/TF313309
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
DPP6 7 ENSG00000130226 1804 DPP6 126141
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Dpp6 5:13-B1 ENSMUSG00000002222 13483 MGI:94921