$VAR1 = undef;
Summary for peptidase homologue S09.973: dipeptidylpeptidase homologue DPP6
| Names | |
|---|---|
| MEROPS Name | dipeptidylpeptidase homologue DPP6 |
| Other names | dipeptidyl-peptidase-like protein-6, DPP6 g.p (Homo sapiens), DPP X, neural membrane CD26 peptidase-like protein |
| Domain architecture |
|---|
| MEROPS Classification | |
|---|---|
| Classification | Clan SC >> Subclan (none) >> Family S9 >> Subfamily X >> S09.973 |
| Holotype | dipeptidylpeptidase homologue DPP6 (Homo sapiens), Uniprot accession P42658 (peptidase unit: 586-849), MERNUM MER0000403 |
| History | Identifier created: MEROPS 5.00 (20 April 2000) |
| Activity | |||
|---|---|---|---|
| Catalytic type | Non-peptidase homologue | ||
| NC-IUBMB | Not yet included in IUBMB recommendations. | ||
| Activity status | human: inactive mouse: inactive | ||
| Knockout | The mouse rump white (Rw) mutation causes a pigmentation defect in heterozygotes and embryonic lethality in homozygotes. The recessive lethality is probably due to the disruption of the gene encoding dipeptidylpeptidase-like protein DPP6 (Hough et al., 1998). | ||
| Other databases | TREEFAM | http://www.treefam.org/family/TF313309 | |
| Human genetics | ||||||
|---|---|---|---|---|---|---|
| Gene symbol | Locus | Megabases | Ensembl | Entrez gene | Gene Cards | OMIM |
| DPP6 | 7 | ENSG00000130226 | 1804 | DPP6 | 126141 | |
| Mouse genetics | ||||||
| Gene symbol | Position | Megabases | Ensembl | Entrez gene | MGI | |
| Dpp6 | 5:13-B1 | ENSMUSG00000002222 | 13483 | MGI:94921 | ||
