Summary for peptidase S08.022: bpr peptidase (Dichelobacter nodosus)

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

 

Names
MEROPS Namebpr peptidase (Dichelobacter nodosus)
Other namesbprB g.p. (Dichelobacter), bprV g.p. (Dichelobacter)
Domain architecture
MEROPS Classification
Classification Clan SB >> Subclan (none) >> Family S8 >> Subfamily A >> S08.022
Holotypebpr peptidase (Dichelobacter nodosus), Uniprot accession P42779 (peptidase unit: 139-469), MERNUM MER0000362
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeSerine
NC-IUBMBNot yet included in IUBMB recommendations.
PhysiologyImplicated in pathogenesis of sheep foot-rot.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/-Scissile bond-/-/-/- (based on 12 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 2 1 0 1 1 1 2
Pro 0 0 1 0 0 0 1 1
Ala 0 1 1 0 1 1 0 0
Val 2 1 1 1 0 1 1 0
Leu 0 0 2 2 2 2 2 0
Ile 0 0 0 0 0 0 0 0
Met 0 0 0 0 0 0 0 0
Phe 1 1 1 2 1 1 1 0
Tyr 1 0 0 2 2 1 0 2
Trp 0 0 0 0 0 0 0 0
Ser 1 0 0 0 0 0 1 1
Thr 0 1 0 0 0 1 1 0
Cys 0 0 0 0 0 0 0 0
Asn 1 1 1 1 0 0 0 0
Gln 0 1 1 1 1 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 2 1 1 0 1 0 0 0
Lys 0 0 0 1 0 0 0 1
Arg 1 1 0 1 0 0 0 0
His 0 1 1 1 1 1 0 1