$VAR1 = undef;

Summary for peptidase S08.012: PfSUB1 peptidase

Names
MEROPS Name	PfSUB1 peptidase
Other names	PfSUB-1 protease, subtilisin-like peptidase 1 (Plasmodium sp.), subtilisin-like protease 1 (Plasmodium sp.)

Domain architecture

MEROPS Classification
Classification	Clan SB >> Subclan (none) >> Family S8 >> Subfamily A >> S08.012
Holotype	PfSUB1 peptidase (Plasmodium falciparum) (peptidase unit: 332-690), MERNUM MER0004690
History	Identifier created: MEROPS 5.1 (22 June 2000)

Activity
Catalytic type	Serine
NC-IUBMB	Not yet included in IUBMB recommendations.
Proteolytic events	CutDB database (1 cleavage)
Other databases	PANTHER	http://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR42884:SF17
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	VI/tks/AG/qdedsnt/edi/td/- (based on 23 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	0	0	10	0	0	0	0	2
Pro	0	0	0	0	0	0	1	2
Ala	0	0	13	1	2	0	2	0
Val	13	1	0	0	0	2	0	1
Leu	1	0	0	0	0	0	0	0
Ile	8	0	0	0	0	4	0	4
Met	0	0	0	0	0	0	0	0
Phe	0	2	0	0	0	0	2	0
Tyr	0	1	0	0	0	0	0	0
Trp	0	0	0	0	0	0	0	0
Ser	0	4	0	0	6	2	1	4
Thr	1	6	0	2	3	3	8	1
Cys	0	0	0	0	0	0	0	0
Asn	0	0	0	2	3	1	0	3
Gln	0	2	0	10	0	0	1	0
Asp	0	0	0	4	8	5	5	3
Glu	0	0	0	4	1	6	3	2
Lys	0	5	0	0	0	0	0	1
Arg	0	1	0	0	0	0	0	0
His	0	1	0	0	0	0	0	0