$VAR1 = undef;

Summary for peptidase homologue S01.976: hepatocyte growth factor

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Pharma

 

Names
MEROPS Namehepatocyte growth factor
Other namesscatter factor, HGF/SF
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily A >> S01.976
Holotypehepatocyte growth factor (Homo sapiens), Uniprot accession P14210 (peptidase unit: 452-723), MERNUM MER0000185
History Identifier created: MEROPS 5.00 (20 April 2000)
Activity
Catalytic typeNon-peptidase homologue
NC-IUBMBNot yet included in IUBMB recommendations.
Pathways KEGGCytokine-cytokine receptor interaction
KEGGFocal adhesion
KEGGMalaria
KEGGMelanoma
KEGGPI3K-Akt signaling pathway
KEGGProteoglycans in cancer
KEGGRap1 signaling pathway
KEGGRas signaling pathway
KEGGRenal cell carcinoma
Other databases TREEFAMhttp://www.treefam.org/family/TF329901
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
HGF 7q21.1 ENSG00000019991 3082 HGF 142409