$VAR1 = undef;

Summary for peptidase S01.270: exfoliatin A

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature

 

Names
MEROPS Nameexfoliatin A
Other namesexfoliative toxin A (Staphylococcus aureas), epidermolysin A, epidermolytic toxin
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily B >> S01.270
Holotypeexfoliatin A (Staphylococcus aureus), Uniprot accession P09331 (peptidase unit: 60-280), MERNUM MER0000261
History Identifier created: MEROPS 3.30 (20 July 1999)
Activity
Catalytic typeSerine
NC-IUBMBNot yet included in IUBMB recommendations.
Pharmaceutical relevanceDegrades desmoglein to cause the skin lesion in staphylococcal scalded skin syndrome (Amagai et al., 2000; Hanakawa & Stanley, 2004).
Other databases WIKIPEDIAhttp://en.wikipedia.org/wiki/Exfoliatin