$VAR1 = undef;

Summary for peptidase M09.005: collagenase ColT (Clostridium tetani)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

 

Names
MEROPS Namecollagenase ColT (Clostridium tetani)
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(E) >> Family M9 >> Subfamily B >> M09.005
Holotypecollagenase ColT (Clostridium tetani) (peptidase unit: 62-506), MERNUM MER0029410
History Identifier created: MEROPS 12.1 (26 Apr 2019)
Activity
Catalytic typeMetallo
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/G/pal/-Scissile bondGa/p/-/g (based on 281 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 26 199 2 20 157 24 34 72
Pro 26 1 83 58 1 81 54 20
Ala 39 16 53 27 68 34 22 30
Val 19 3 15 6 3 10 24 10
Leu 17 1 42 27 5 28 26 15
Ile 0 4 4 1 2 9 16 10
Met 6 2 5 21 5 6 2 5
Phe 4 2 1 30 4 10 13 8
Tyr 3 8 0 21 1 6 5 4
Trp 1 0 4 5 2 0 0 1
Ser 23 6 11 11 14 12 9 22
Thr 19 0 12 4 0 11 20 8
Cys 3 0 2 7 0 1 5 2
Asn 4 3 12 2 0 10 3 12
Gln 15 6 23 25 0 15 7 19
Asp 32 0 1 2 2 7 10 15
Glu 23 3 1 7 0 5 19 20
Lys 8 11 1 0 3 3 1 3
Arg 4 15 2 0 0 0 2 0
His 9 1 7 7 14 9 9 5