$VAR1 = undef;

Summary for peptidase M04.017: griselysin

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS Namegriselysin
Other namesmetalloendopeptidase I (Streptomyces griseus), metalloendopeptidase II (Streptomyces griseus), neutral endopeptidase (Streptomyces griseus), Npr protease (Streptomyces sp.), pronase metalloendopeptidase component, Streptomyces griseus metalloprotease I, Streptomyces griseus metalloprotease II, SGMP I, SGMP II, TAMEP, TGase-activating protease (Streptomyces mobaraensis), transglutaminase-activating metalloendopeptidase (Streptomyces mobaraensis)
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(E) >> Family M4 >> Subfamily (none) >> M04.017
Holotypegriselysin (Streptomyces griseus) (peptidase unit: 1-320), MERNUM MER0004744
History Identifier created: MEROPS 5.4 (23 March 2001)
Activity
Catalytic typeMetallo
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (1 cleavage)
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/gf/GfScissile bondL/Agl/g/- (based on 36 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 1 1 5 26 0 7 3 0
Pro 0 1 1 0 0 0 1 1
Ala 1 1 1 1 2 18 2 1
Val 0 0 0 0 2 0 0 0
Leu 0 0 0 0 23 2 0 0
Ile 0 0 0 0 2 0 0 0
Met 0 0 0 0 0 0 0 0
Phe 0 2 2 8 3 1 1 0
Tyr 0 0 0 0 2 0 0 0
Trp 0 0 0 0 1 0 0 0
Ser 0 0 1 1 0 0 0 0
Thr 0 0 0 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 0 0 0 0
Gln 0 0 0 0 0 0 0 0
Asp 0 0 0 0 0 0 0 1
Glu 0 0 0 0 0 0 0 0
Lys 0 0 0 0 0 0 0 0
Arg 0 0 0 0 1 1 0 0
His 0 0 0 0 0 0 0 0