$VAR1 = undef;

Summary for peptidase C02.018: calpain-10

Names
MEROPS Name	calpain-10
Other names	CAPN8 g.p. [obs.] (Mus musculus), CAPN10 g.p. (Homo sapiens, Mus musculus)

Domain architecture

MEROPS Classification
Classification	Clan CA >> Subclan (none) >> Family C2 >> Subfamily A >> C02.018
Holotype	calpain-10 (Homo sapiens), Uniprot accession Q9HC96 (peptidase unit: 43-304), MERNUM MER0013510
History	Identifier created: MEROPS 5.3 (4 December 2000)

Activity
Catalytic type	Cysteine
NC-IUBMB	Not yet included in IUBMB recommendations.
Activity status	human: putative mouse: putative
Physiology	It is reported that variations in the gene are associated with type 2 diabetes, and affect blood glucose levels through changes in the early insulin secretory response (Lynn et al., 2002). The association with type 2 diabetes is found in Mexican Americans but not in Japanese (Horikawa et al., 2003).
Other databases	WIKIPEDIA	http://en.wikipedia.org/wiki/Calpain-10