E167K RF2 on E. coli 70S release complex with UGG (Structure I)
Pundir S, Larsson DSD, Selmer M, Sanyal S
To Be Published
- Small ribosomal subunit protein us3 (26 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us12 (13 kDa, Protein from Escherichia coli)
- Ribosome release complex (2 MDa, Complex from Escherichia coli)
- Small ribosomal subunit protein us17 (9 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us8 (14 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs18 (9 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us15 (10 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs20 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us11 (13 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s7 (20 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l23 (11 kDa, Protein from Escherichia coli)
- Peptide chain release factor rf2 (41 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s6 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us2 (26 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l11 (14 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us19 (10 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us13 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l27 (9 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul16 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- Spermine (202 Da, Ligand)
- Small ribosomal subunit protein bs16 (9 kDa, Protein from Escherichia coli)
- Trna(fmet) (24 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l17 (14 kDa, Protein from Escherichia coli)
- Potassium ion (39 Da, Ligand)
- 50s ribosomal protein l28 (9 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us14 (11 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs21 (8 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us9 (14 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us4 (23 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us10 (11 kDa, Protein from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- 1,4-diaminobutane (88 Da, Ligand)
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl31a (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli)
- Spermidine (145 Da, Ligand)
- 16s rrna (499 kDa, RNA from Escherichia coli)
- Mrna (15 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l33 (6 kDa, Protein from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us5 (17 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 23s rrna (941 kDa, RNA from Escherichia coli)
- 5s rrna (38 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli)
E167K RF2 on E. coli 70S release complex with UGG (Structure II)
Resolution: 2.78 Å
EM Method: Single-particle
Fitted PDBs: 8p17
Q-score: 0.545
Pundir S, Larsson DSD, Selmer M, Sanyal S
To Be Published
- Small ribosomal subunit protein us3 (26 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us12 (13 kDa, Protein from Escherichia coli)
- Ribosome release complex (2 MDa, Complex from Escherichia coli)
- Small ribosomal subunit protein us17 (9 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us8 (14 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs18 (9 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us15 (10 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs20 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us11 (13 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s7 (20 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l23 (11 kDa, Protein from Escherichia coli)
- 16s rna (499 kDa, RNA from Escherichia coli)
- Peptide chain release factor rf2 (41 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s6 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us2 (26 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l11 (14 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us19 (10 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us13 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l27 (9 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul16 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- Spermine (202 Da, Ligand)
- Small ribosomal subunit protein bs16 (9 kDa, Protein from Escherichia coli)
- Trna(fmet) (24 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l17 (14 kDa, Protein from Escherichia coli)
- Potassium ion (39 Da, Ligand)
- 50s ribosomal protein l28 (9 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us14 (11 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs21 (8 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us9 (14 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us4 (23 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us10 (11 kDa, Protein from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- 1,4-diaminobutane (88 Da, Ligand)
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl31a (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli)
- Spermidine (145 Da, Ligand)
- Mrna (15 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l33 (6 kDa, Protein from Escherichia coli)
- Water (18 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us5 (17 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 23s rrna (941 kDa, RNA from Escherichia coli)
- 5s rrna (38 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli)
E167K RF2 on E. coli 70S release complex with UGG (Structure III)
Pundir S, Larsson DSD, Selmer M, Sanyal S
To Be Published
- Small ribosomal subunit protein us3 (26 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us12 (13 kDa, Protein from Escherichia coli)
- Ribosome release complex (2 MDa, Complex from Escherichia coli)
- Small ribosomal subunit protein us17 (9 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us8 (14 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs18 (9 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us15 (10 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs20 (9 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l20 (13 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us11 (13 kDa, Protein from Escherichia coli)
- 30s ribosomal protein s7 (20 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l22 (12 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l23 (11 kDa, Protein from Escherichia coli)
- Peptide chain release factor rf2 (41 kDa, Protein from Escherichia coli K-12)
- 30s ribosomal protein s6 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l36 (4 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l13 (16 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us2 (26 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein bl31 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l11 (14 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us19 (10 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us13 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l14 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l27 (9 kDa, Protein from Escherichia coli)
- Large ribosomal subunit protein ul16 (15 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l4 (22 kDa, Protein from Escherichia coli)
- Spermine (202 Da, Ligand)
- Small ribosomal subunit protein bs16 (9 kDa, Protein from Escherichia coli)
- Trna(fmet) (24 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l5 (20 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l17 (14 kDa, Protein from Escherichia coli)
- Potassium ion (39 Da, Ligand)
- 50s ribosomal protein l28 (9 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us14 (11 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein bs21 (8 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l18 (12 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us9 (14 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l9 (15 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us4 (23 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us10 (11 kDa, Protein from Escherichia coli)
- Zinc ion (65 Da, Ligand)
- 1,4-diaminobutane (88 Da, Ligand)
- 50s ribosomal protein l24 (11 kDa, Protein from Escherichia coli)
- Spermidine (145 Da, Ligand)
- 50s ribosomal protein l34 (5 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l21 (11 kDa, Protein from Escherichia coli)
- 16s rrna (499 kDa, RNA from Escherichia coli)
- Mrna (15 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l19 (13 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l35 (7 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l33 (6 kDa, Protein from Escherichia coli)
- Water (18 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- 50s ribosomal protein l6 (18 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l32 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l15 (15 kDa, Protein from Escherichia coli)
- Small ribosomal subunit protein us5 (17 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l2 (29 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l30 (6 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l25 (10 kDa, Protein from Escherichia coli)
- 50s ribosomal protein l3 (22 kDa, Protein from Escherichia coli)
- 23s rrna (941 kDa, RNA from Escherichia coli)
- 5s rrna (38 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l29 (7 kDa, Protein from Escherichia coli)
Resolution: 2.44 Å
EM Method: Single-particle
Fitted PDBs: 8p2f
Q-score: 0.597
Gonzalez-Lopez A, Larsson D, Nelson B, Hergenrother PJ, Selmer M
To Be Published
- 30s ribosomal protein s4 (23 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s6 (11 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l29 (8 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l19 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l22 (12 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s10 (11 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l33 1 (5 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s17 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l4 (22 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s5 (17 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s12 (15 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s13 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l25 (23 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l27 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 23s ribosomal rna (946 kDa, RNA from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s16 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 2-[(3~{r},4~{s},5~{s},8~{s},9~{s},10~{s},11~{r},13~{s},14~{s},16~{s})-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-1,2,3,4,5,6,7,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5-cyclopentyl-pentanoic acid (546 Da, Ligand)
- 50s ribosomal protein l30 (6 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l32 (6 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l20 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s20 (9 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l24 (11 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l36 (4 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s18 (9 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l21 (11 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s11 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l31 type b (9 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- 50s ribosomal protein l35 (7 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- Potassium ion (39 Da, Ligand)
- 50s ribosomal protein l17 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- Zinc ion (65 Da, Ligand)
- 50s ribosomal protein l3 (23 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 16s ribosomal rna (503 kDa, RNA from Staphylococcus aureus subsp. aureus NCTC 8325)
- 1,4-diaminobutane (88 Da, Ligand)
- 50s ribosomal protein l18 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- Spermidine (145 Da, Ligand)
- 50s ribosomal protein l23 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- Staphylococcus aureus 70s ribosome with elongation factor g and fusidic acid cyclopentane (2 MDa, Complex from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s3 (24 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s14 type z (7 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- Water (18 Da, Ligand)
- 50s ribosomal protein l2 (30 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l28 (6 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- Mrna (7 kDa, RNA from Escherichia coli)
- Magnesium ion (24 Da, Ligand)
- 5s ribosomal rna (36 kDa, RNA from Staphylococcus aureus subsp. aureus NCTC 8325)
- Trna (24 kDa, RNA from Escherichia coli)
- 50s ribosomal protein l15 (15 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s2 (29 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s7 (17 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s8 (14 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- Elongation factor g (76 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l5 (20 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s9 (14 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s15 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l16 (16 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l14 (13 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 30s ribosomal protein s19 (10 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l34 (5 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l6 (19 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
- 50s ribosomal protein l13 (16 kDa, Protein from Staphylococcus aureus subsp. aureus NCTC 8325)
Cryo-EM Structure of Human Kv3.1 in Complex with Modulator AUT1
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8quc
Q-score: 0.551
Liang Q, Chi G, Cirqueira L, Zhi L, Marasco A, Pilati N, Gunthorpe MJ, Alvaro G, Large CH, Sauer DB, Treptow W, Covarrubias M
Nat Commun (2024) 15 pp. 2533-2533 [ Pubmed: 38514618 DOI: doi:10.1038/s41467-024-46813-8 ]
- Cholesterol hemisuccinate (486 Da, Ligand)
- (5r)-5-ethyl-3-[6-(3-methoxy-4-methyl-phenoxy)pyridin-3-yl]imidazolidine-2,4-dione (341 Da, Ligand)
- Potassium voltage-gated channel subfamily c member 1 (58 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Homotetramer of human kv3.1a with modulator aut1 (240 kDa, Complex from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phoshocholine (734 Da, Ligand)
Cryo-EM Structure of Human Kv3.1 in Complex with Modulator AUT5
Resolution: 2.5 Å
EM Method: Single-particle
Fitted PDBs: 8qud
Q-score: 0.555
Liang Q, Chi G, Cirqueira L, Zhi L, Marasco A, Pilati N, Gunthorpe MJ, Alvaro G, Large CH, Sauer DB, Treptow W, Covarrubias M
Nat Commun (2024) 15 pp. 2533-2533 [ Pubmed: 38514618 DOI: doi:10.1038/s41467-024-46813-8 ]
- Cholesterol hemisuccinate (486 Da, Ligand)
- Homotetramer of human kv3.1a with modulator aut5 (240 kDa, Complex from Homo sapiens)
- Potassium voltage-gated channel subfamily c member 1 (58 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- (5r)-5-ethyl-3-(6-spiro[2h-1-benzofuran-3,1'-cyclopropane]-4-yloxypyridin-3-yl)imidazolidine-2,4-dione (365 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phoshocholine (734 Da, Ligand)
Potassium transporter KtrAB from Bacillus subtilis in ADP-bound state
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 8k1s
Q-score: 0.482
Chiang WT, Chang YK, Hui WH, Chang SW, Liao CY, Chang YC, Chen CJ, Wang WC, Lai CC, Wang CH, Luo SY, Huang YP, Chou SH, Horng TL, Hou MH, Muench SP, Chen RS, Tsai MD, Hu NJ
Nat Commun (2024) 15 pp. 3850-3850 [ Pubmed: 38719864 DOI: doi:10.1038/s41467-024-48057-y ]
- Ktr system potassium uptake protein a (24 kDa, Protein from Bacillus subtilis)
- Ktrb dimer (Complex)
- Bacillus subtilis ktrab potassium transporter (199 kDa, Complex from Bacillus subtilis)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Potassium ion (39 Da, Ligand)
- Ktr system potassium uptake protein b (48 kDa, Protein from Bacillus subtilis)
- Ktra octamer (Complex from Bacillus subtilis)
Potassium transporter KtrAB from Bacillus subtilis in ATP-bound state with addition of MgCl2
Resolution: 2.48 Å
EM Method: Single-particle
Fitted PDBs: 8k1t
Q-score: 0.573
Chiang WT, Chang YK, Hui WH, Chang SW, Liao CY, Chang YC, Chen CJ, Wang WC, Lai CC, Wang CH, Luo SY, Huang YP, Chou SH, Horng TL, Hou MH, Muench SP, Chen RS, Tsai MD, Hu NJ
Nat Commun (2024) 15 pp. 3850-3850 [ Pubmed: 38719864 DOI: doi:10.1038/s41467-024-48057-y ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Ktr system potassium uptake protein a (24 kDa, Protein from Bacillus subtilis)
- Ktrb dimer (Complex)
- Bacillus subtilis ktrab potassium transporter (199 kDa, Complex from Bacillus subtilis)
- Ktra octamer (97 kDa, Complex from Bacillus subtilis)
- Potassium ion (39 Da, Ligand)
- Ktr system potassium uptake protein b (48 kDa, Protein from Bacillus subtilis)
Potassium transporter KtrAB from Bacillus subtilis in ATP-bound state with addition of EDTA and EGTA
Resolution: 2.82 Å
EM Method: Single-particle
Fitted PDBs: 8k1u
Q-score: 0.517
Chiang WT, Chang YK, Hui WH, Chang SW, Liao CY, Chang YC, Chen CJ, Wang WC, Lai CC, Wang CH, Luo SY, Huang YP, Chou SH, Horng TL, Hou MH, Muench SP, Chen RS, Tsai MD, Hu NJ
Nat Commun (2024) 15 pp. 3850-3850 [ Pubmed: 38719864 DOI: doi:10.1038/s41467-024-48057-y ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Ktr system potassium uptake protein a (24 kDa, Protein from Bacillus subtilis)
- Ktrb dimer (Complex)
- Bacillus subtilis ktrab potassium transporter (199 kDa, Complex from Bacillus subtilis)
- Potassium ion (39 Da, Ligand)
- Ktr system potassium uptake protein b (48 kDa, Protein from Bacillus subtilis)
- Ktra octamer (Complex from Bacillus subtilis)
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8xmh
Q-score: 0.524
Chiang WT, Chang YK, Hui WH, Chang SW, Liao CY, Chang YC, Chen CJ, Wang WC, Lai CC, Wang CH, Luo SY, Huang YP, Chou SH, Horng TL, Hou MH, Muench SP, Chen RS, Tsai MD, Hu NJ
Nat Commun (2024) 15 pp. 3850-3850 [ Pubmed: 38719864 DOI: doi:10.1038/s41467-024-48057-y ]
- Bacillus subtilis ktrab potassium transporter ktrab (199 kDa, Complex from Bacillus subtilis)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Sodium ion (22 Da, Ligand)
- Ktr system potassium uptake protein a (24 kDa, Protein from Bacillus subtilis)
- Ktrb dimer (Complex)
- Potassium ion (39 Da, Ligand)
- Ktr system potassium uptake protein b (48 kDa, Protein from Bacillus subtilis)
- Ktra octamer (Complex from Bacillus subtilis)