Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7xog
Q-score: 0.294
Tan S, Zhao J, Hu X, Li Y, Wu Z, Lu G, Yu Z, Du B, Liu Y, Li L, Chen Y, Li Y, Yao Y, Zhang X, Rao J, Gao G, Peng Y, Liu H, Yuan Z, Liu J, Wang Q, Hu H, Gao X, Zhou H, Yu H, Xu Y, Yu W, Feng L, Wang M, Shan C, Lu J, Lin J
Sci Bull (Beijing) (2023) 68 pp. 3192-3206 [ Pubmed: 37993332 DOI: doi:10.1016/j.scib.2023.11.024 ]
- Spike glycoprotein,peptide (142 kDa, Protein from synthetic construct)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Severe acute respiratory syndrome coronavirus (Complex from Severe acute respiratory syndrome coronavirus)
- Alpha-d-mannopyranose (180 Da, Ligand)
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7xoe
Q-score: 0.301
Tan S, Zhao J, Hu X, Li Y, Wu Z, Lu G, Yu Z, Du B, Liu Y, Li L, Chen Y, Li Y, Yao Y, Zhang X, Rao J, Gao G, Peng Y, Liu H, Yuan Z, Liu J, Wang Q, Hu H, Gao X, Zhou H, Yu H, Xu Y, Yu W, Feng L, Wang M, Shan C, Lu J, Lin J
Sci Bull (Beijing) (2023) 68 pp. 3192-3206 [ Pubmed: 37993332 DOI: doi:10.1016/j.scib.2023.11.024 ]
Cryo-EM structure of human ABCA4 in the apo state
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7e7i
Q-score: 0.525
Xie T, Zhang Z, Fang Q, Du B, Gong X
Nat Commun (2021) 12 pp. 3853-3853 [ Pubmed: 34158497 DOI: doi:10.1038/s41467-021-24194-6 ]
- Retinal-specific phospholipid-transporting atpase abca4 (261 kDa, Protein from Homo sapiens)
- Abca4 (Complex from Homo sapiens)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
Cryo-EM structure of human ABCA4 in NRPE-bound state
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7e7o
Q-score: 0.518
Xie T, Zhang Z, Fang Q, Du B, Gong X
Nat Commun (2021) 12 pp. 3853-3853 [ Pubmed: 34158497 DOI: doi:10.1038/s41467-021-24194-6 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- [(2s)-3-[2-[(e)-[(2e,4e,6e,8e)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenylidene]amino]ethoxy-oxidanyl-phosphoryl]oxy-2-[(z)-octadec-9-enoyl]oxy-propyl] (z)-octadec-9-enoate (1 kDa, Ligand)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Retinal-specific phospholipid-transporting atpase abca4 (261 kDa, Protein from Homo sapiens)
- Nrpe-bound abca4 (Complex from Homo sapiens)
Cryo-EM structure of human ABCA4 in ATP-bound state
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7e7q
Q-score: 0.532
Xie T, Zhang Z, Fang Q, Du B, Gong X
Nat Commun (2021) 12 pp. 3853-3853 [ Pubmed: 34158497 DOI: doi:10.1038/s41467-021-24194-6 ]
- 2-acetamido-2-deoxy-beta-d-glucopyranose (221 Da, Ligand)
- Atp-bound abca4 (Complex from Homo sapiens)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Retinal-specific phospholipid-transporting atpase abca4 (261 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)