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Taf15 amyloid filaments - Individual 2
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2023) 625 pp. 345-351 [ Pubmed: 38057661 DOI: 10.1038/s41586-023-06801-2 ]
Image sets:
Taf15, TMEM106B and Aß42 amyloid filaments - Individual 4, frontal cortex
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2023) 625 pp. 345-351 [ Pubmed: 38057661 DOI: 10.1038/s41586-023-06801-2 ]
Image sets:
Taf15, TMEM106B and Aß42 amyloid filaments - Individual 4, brainstem
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2023) 625 pp. 345-351 [ DOI: 10.1038/s41586-023-06801-2 Pubmed: 38057661 ]
Image sets:
CTE typeI tau filament from Guam ALS/PDC
Resolution: 2.0 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ot6
Q-score: 0.709
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Tau filaments from guam als/pdc (Complex from Homo sapiens)
- Microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
CTE typeIII tau filament from Guam ALS/PDC
Resolution: 3.4 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ot9
Q-score: 0.551
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Tau filaments from guam als/pdc (Complex from Homo sapiens)
- Microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
CTE typeII tau filament from Guam ALS/PDC
Resolution: 3.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 8otc
Q-score: 0.481
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Tau filaments from guam als/pdc (Complex from Homo sapiens)
- Microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
TMEM106B Fold1-s filament from Guam ALS/PDC
Resolution: 2.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 8otd
Q-score: 0.61
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Tau filaments from guam als/pdc (Complex from Homo sapiens)
- Transmembrane protein 106b (31 kDa, Protein from Homo sapiens)
TMEM106B Fold I-d filament from Guam ALS/PDC
Resolution: 3.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ote
Q-score: 0.474
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Tmem106b fold1-d filaments from guam als/pdc (Complex from Homo sapiens)
- Transmembrane protein 106b (31 kDa, Protein from Homo sapiens)
Ab typeII filament from Guam ALS/PDC
Resolution: 3.3 Å
EM Method: Helical reconstruction
Fitted PDBs: 8otf
Q-score: 0.564
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Ab typeii filaments from guam als/pdc (Complex from Homo sapiens)
- Amyloid-beta precursor protein (87 kDa, Protein from Homo sapiens)
CTE typeI tau filament from Kii ALS/PDC
Resolution: 2.1 Å
EM Method: Helical reconstruction
Fitted PDBs: 8otg
Q-score: 0.681
Qi C, Verheijen BM, Kokubo Y, Shi Y, Tetter S, Murzin AG, Nakahara A, Morimoto S, Vermulst M, Sasaki R, Aronica E, Hirokawa Y, Oyanagi K, Kakita A, Ryskeldi-Falcon B, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
PNAS (2023) 120 pp. e2306767120-e2306767120 [ DOI: doi:10.1073/pnas.2306767120 Pubmed: 38100415 ]
- Microtubule-associated protein tau (45 kDa, Protein from Homo sapiens)
- Typei tau filaments from kii als/pdc (Complex from Homo sapiens)