Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 8fpv
Q-score: 0.555
Nakagawa T, Wang XT, Miguez-Cabello FJ, Bowie D
Nat Struct Mol Biol (2024) 31 pp. 688-700 [ DOI: doi:10.1038/s41594-024-01228-3 Pubmed: 38409505 ]
- Glua2 flip q isoform of ampa receptor in complex with gain-of-function tarp gamma-2 (kk52ee) (500 kDa, Complex from Rattus norvegicus)
- Cyclothiazide (389 Da, Ligand)
- Glutamic acid (147 Da, Ligand)
- Glutamate receptor 2 (99 kDa, Protein from Rattus norvegicus)
- Water (18 Da, Ligand)
Resolution: 2.98 Å
EM Method: Single-particle
Fitted PDBs: 8fpy
Q-score: 0.545
Nakagawa T, Wang XT, Miguez-Cabello FJ, Bowie D
Nat Struct Mol Biol (2024) 31 pp. 688-700 [ DOI: doi:10.1038/s41594-024-01228-3 Pubmed: 38409505 ]
- Glua2 flip q isoform of ampa receptor in complex with gain-of-function tarp gamma-2 (kk52ee) (500 kDa, Complex from Rattus norvegicus)
- Cyclothiazide (389 Da, Ligand)
- Glutamic acid (147 Da, Ligand)
- Glutamate receptor 2 (99 kDa, Protein from Rattus norvegicus)
- Water (18 Da, Ligand)
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 8fpz
Q-score: 0.531
Nakagawa T, Wang XT, Miguez-Cabello FJ, Bowie D
Nat Struct Mol Biol (2024) 31 pp. 688-700 [ DOI: doi:10.1038/s41594-024-01228-3 Pubmed: 38409505 ]
- Glua2 flip q isoform of ampa receptor in complex with gain-of-function tarp gamma-2 (kk52ee) (500 kDa, Complex from Rattus norvegicus)
- Cyclothiazide (389 Da, Ligand)
- Glutamic acid (147 Da, Ligand)
- Glutamate receptor 2 (99 kDa, Protein from Rattus norvegicus)
- Water (18 Da, Ligand)
Resolution: 3.35 Å
EM Method: Single-particle
Fitted PDBs: 8fqa
Q-score: 0.457
Nakagawa T, Wang XT, Miguez-Cabello FJ, Bowie D
Nat Struct Mol Biol (2024) 31 pp. 688-700 [ DOI: doi:10.1038/s41594-024-01228-3 Pubmed: 38409505 ]
- Cyclothiazide (389 Da, Ligand)
- Glutamic acid (147 Da, Ligand)
- Glutamate receptor 2 (99 kDa, Protein from Rattus norvegicus)
- Water (18 Da, Ligand)
- Homotetrameric assembly of glua2 flip-q isoform in complex with tarp gamma2 (k52e, k53e). dimer-of-dimers assembly. (500 kDa, Complex from Rattus norvegicus)
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 8fp4
Q-score: 0.645
Nakagawa T, Wang XT, Miguez-Cabello FJ, Bowie D
Nat Struct Mol Biol (2024) 31 pp. 688-700 [ DOI: doi:10.1038/s41594-024-01228-3 Pubmed: 38409505 ]
- Voltage-dependent calcium channel gamma-2 subunit (37 kDa, Protein from Mus musculus)
- Chloride ion (35 Da, Ligand)
- Glutamate receptor 2 (99 kDa, Protein from Rattus norvegicus)
- Water (18 Da, Ligand)
- Glua2 flip q isoform of ampa receptor in complex with gain-of-function tarp gamma-2 (kk52ee) (500 kDa, Complex from Rattus)
Resolution: 2.44 Å
EM Method: Single-particle
Fitted PDBs: 8fp9
Q-score: 0.629
Nakagawa T, Wang XT, Miguez-Cabello FJ, Bowie D
Nat Struct Mol Biol (2024) 31 pp. 688-700 [ DOI: doi:10.1038/s41594-024-01228-3 Pubmed: 38409505 ]
- Voltage-dependent calcium channel gamma-2 subunit (37 kDa, Protein from Mus musculus)
- Chloride ion (35 Da, Ligand)
- Glutamate receptor 2 (99 kDa, Protein from Rattus norvegicus)
- Water (18 Da, Ligand)
- Calcium ion (40 Da, Ligand)
- Glua2 flip-q isoform in complex with tarp gamma2 (k52e, k53e) (500 kDa, Complex from Rattus norvegicus)
Resolution: 2.78 Å
EM Method: Single-particle
Fitted PDBs: 8fpc
Q-score: 0.59
Nakagawa T, Wang XT, Miguez-Cabello FJ, Bowie D
Nat Struct Mol Biol (2024) 31 pp. 688-700 [ DOI: doi:10.1038/s41594-024-01228-3 Pubmed: 38409505 ]
- Cyclothiazide (389 Da, Ligand)
- Glutamic acid (147 Da, Ligand)
- Glutamate receptor 2 (99 kDa, Protein from Rattus norvegicus)
- Water (18 Da, Ligand)
- Glua2 flip-q isoform in complex with tarp gamma2 (k52e, k53e) (500 kDa, Complex from Rattus norvegicus)
Resolution: 2.32 Å
EM Method: Single-particle
Fitted PDBs: 8fpg
Q-score: 0.636
Nakagawa T, Wang XT, Miguez-Cabello FJ, Bowie D
Nat Struct Mol Biol (2024) 31 pp. 688-700 [ DOI: doi:10.1038/s41594-024-01228-3 Pubmed: 38409505 ]
- Voltage-dependent calcium channel gamma-2 subunit (37 kDa, Protein from Mus musculus)
- Chloride ion (35 Da, Ligand)
- Glutamate receptor 2 (99 kDa, Protein from Rattus norvegicus)
- Water (18 Da, Ligand)
- Glua2 flip-q isoform in complex with tarp gamma2 (k52e, k53e) (500 kDa, Complex from Rattus norvegicus)
Resolution: 3.14 Å
EM Method: Single-particle
Fitted PDBs: 8fph
Q-score: 0.527
Nakagawa T, Wang XT, Miguez-Cabello FJ, Bowie D
Nat Struct Mol Biol (2024) 31 pp. 688-700 [ DOI: doi:10.1038/s41594-024-01228-3 Pubmed: 38409505 ]
- Cyclothiazide (389 Da, Ligand)
- Glutamic acid (147 Da, Ligand)
- Glutamate receptor 2 (99 kDa, Protein from Rattus norvegicus)
- Water (18 Da, Ligand)
- Glua2 flip-q isoform in complex with tarp gamma2 (k52e, k53e) (500 kDa, Complex from Rattus norvegicus)
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 8fpk
Q-score: 0.595
Nakagawa T, Wang XT, Miguez-Cabello FJ, Bowie D
Nat Struct Mol Biol (2024) 31 pp. 688-700 [ DOI: doi:10.1038/s41594-024-01228-3 Pubmed: 38409505 ]
- 6-(aminomethyl)-7-nitro-1,4-dihydroquinoxaline-2,3-dione (236 Da, Ligand)
- Glua2 flip-q isoform in complex with tarp gamma2 (k52e, k53e) (500 kDa, Complex from Rattus norvegicus)
- Glutamate receptor 2 (99 kDa, Protein from Rattus norvegicus)
- Cyclothiazide (389 Da, Ligand)