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EMD-29372

Single-particle
3.01 Å
EMD-29372 Deposition: 05/01/2023
Map released: 06/03/2024
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-29372

LBD conformation 3 (LBDconf3) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 500mM NaCl, 330uM CTZ, and 100mM glutamate (Open-Na610)

EMD-29372

Single-particle
3.01 Å
EMD-29372 Deposition: 05/01/2023
Map released: 06/03/2024
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus
Sample: GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2 (KK52EE)
Fitted models: 8fpz

Deposition Authors: Nakagawa T
The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport.
Nakagawa T , Wang XT , Miguez-Cabello FJ , Bowie D
(2024) Nat Struct Mol Biol , 31 , 688 - 700
PUBMED: 38409505
DOI: doi:10.1038/s41594-024-01228-3
ISSN: 1545-9985