Amyloid beta 42 type 2 filaments from the brainstem of individual 4
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2024) 625 pp. 345-351 [ DOI: doi:10.1038/s41586-023-06801-2 Pubmed: 38057661 ]
TAF15 filaments from brainstem - Individual 4
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2024) 625 pp. 345-351 [ DOI: doi:10.1038/s41586-023-06801-2 Pubmed: 38057661 ]
TAF15 filament - individual 1, motor cortex
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2024) 625 pp. 345-351 [ DOI: doi:10.1038/s41586-023-06801-2 Pubmed: 38057661 ]
singlet TMEM type 1 filament - Individual 4, prefrontal cortex
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2024) 625 pp. 345-351 [ DOI: doi:10.1038/s41586-023-06801-2 Pubmed: 38057661 ]
doublet TMEM type 1 filament - individual 4, brainstem
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2024) 625 pp. 345-351 [ DOI: doi:10.1038/s41586-023-06801-2 Pubmed: 38057661 ]
doublet TMEM106B type 1 filament - individual 4, prefrontal cortex
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2024) 625 pp. 345-351 [ DOI: doi:10.1038/s41586-023-06801-2 Pubmed: 38057661 ]
singlet TMEM type 1 filament - individual 4, brainstem
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2024) 625 pp. 345-351 [ DOI: doi:10.1038/s41586-023-06801-2 Pubmed: 38057661 ]
TAF15 amyloid fold in atypical FTLD - Individual 1
Resolution: 1.97 Å
EM Method: Helical reconstruction
Fitted PDBs: 8ons
Q-score: 0.749
Tetter S, Arseni D, Murzin AG, Buhidma Y, Peak-Chew SY, Garringer HJ, Newell KL, Vidal R, Apostolova LG, Lashley T, Ghetti B, Ryskeldi-Falcon B
Nature (2024) 625 pp. 345-351 [ DOI: doi:10.1038/s41586-023-06801-2 Pubmed: 38057661 ]
- Water (18 Da, Ligand)
- Taf15 atypical ftld amyloid fold (Tissue from Homo sapiens)
- Tata-binding protein-associated factor 2n (61 kDa, Protein from Homo sapiens)
Structure of TDP-43 amyloid filaments from type A FTLD-TDP (individual 1)
Arseni D, Chen R, Murzin AG, Peak-Chew SY, Garringer HJ, Newell KL, Kametani F, Robinson AC, Vidal R, Ghetti B, Hasegawa M, Ryskeldi-Falcon B
Nature (2023) 620 pp. 898-903 [ DOI: 10.1038/s41586-023-06405-w Pubmed: 37532939 ]
Image sets:
Structure of apo telomeric nucleosome
Resolution: 2.52 Å
EM Method: Single-particle
Fitted PDBs: 8ox0
Q-score: 0.607
Hu H, van Roon AM, Ghanim GE, Ahsan B, Oluwole AO, Peak-Chew SY, Robinson CV, Nguyen THD
Sci Adv (2023) 9 pp. eadi4148-eadi4148 [ DOI: doi:10.1126/sciadv.adi4148 Pubmed: 37624885 ]
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Trf1core in complex with telomeric nucleosome (Complex)
- Histone h2b type 1-c/e/f/g/i (14 kDa, Protein from Homo sapiens)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- Human telomeric nucleosome (Complex from Homo sapiens)
- Telomeric dna g strand (46 kDa, DNA from Homo sapiens)
- Histone h2a type 1-c (14 kDa, Protein from Homo sapiens)
- Telomeric dna c strand (43 kDa, DNA from Homo sapiens)