EMD-16628

Helical reconstruction
2.39 Å
EMD-16628
3D View Gallery
Deposition: 03/02/2023
Map released: 02/08/2023
Last modified: 30/08/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-16628

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8cg3 summary report (pdf.gz) Map-8cg3 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 1)

EMD-16628

Helical reconstruction
2.39 Å
EMD-16628
3D View Gallery
Deposition: 03/02/2023
Map released: 02/08/2023
Last modified: 30/08/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: TDP-43 amyloid filaments extracted from the frontal cortex of an individual with type A FTLD-TDP
Fitted models: 8cg3

Deposition Authors: Arseni D , Ryskeldi-Falcon B
TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.
Arseni D , Chen R, Murzin AG, Peak-Chew SY, Garringer HJ , Newell KL, Kametani F , Robinson AC , Vidal R , Ghetti B , Hasegawa M , Ryskeldi-Falcon B
(2023) Nature , 620 , 898 - 903
PUBMED: 37532939
DOI: doi:10.1038/s41586-023-06405-w
ISSN: 1476-4687
ASTM: NATUAS