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EMD-22009
Structure of human TRPA1 in complex with agonist GNE551
EMD-22009
Single-particle3.0 Å
Deposition: 20/05/2020Map released: 18/11/2020
Last modified: 06/03/2024
Sample Organism:
Homo sapiens
Sample: TRPA1 bound by agonist GNE551
Fitted models: 6x2j
Deposition Authors: Rohou A, Rouge L
,
Chen H
Sample: TRPA1 bound by agonist GNE551
Fitted models: 6x2j
Deposition Authors: Rohou A, Rouge L
,
Chen H
A Non-covalent Ligand Reveals Biased Agonism of the TRPA1 Ion Channel.
Liu C ,
Reese R,
Vu S,
Rouge L ,
Shields SD ,
Kakiuchi-Kiyota S,
Chen H,
Johnson K ,
Shi YP,
Chernov-Rogan T,
Greiner DMZ,
Kohli PB,
Hackos D,
Brillantes B,
Tam C,
Li T,
Wang J,
Safina B,
Magnuson S,
Volgraf M,
Payandeh J,
Zheng J,
Rohou A,
Chen J
(2021) Neuron , 109 , 273 - 284.e4
,
Reese R,
Vu S,
Rouge L ,
Shields SD ,
Kakiuchi-Kiyota S,
Chen H,
Johnson K ,
Shi YP,
Chernov-Rogan T,
Greiner DMZ,
Kohli PB,
Hackos D,
Brillantes B,
Tam C,
Li T,
Wang J,
Safina B,
Magnuson S,
Volgraf M,
Payandeh J,
Zheng J,
Rohou A,
Chen J
(2021) Neuron , 109 , 273 - 284.e4