6x2j

Electron Microscopy
3Å resolution

Structure of human TRPA1 in complex with agonist GNE551

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transient receptor potential cation channel subfamily A member 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 631 amino acids
Theoretical weight: 72.62 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O75762 (Residues: 448-1078; Coverage: 56%)
Gene names: ANKTM1, TRPA1
Sequence domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution:
Relevant EMDB volumes: EMD-22009
Expression system: Spodoptera frugiperda