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EMD-20488
Human alpha3beta4 nicotinic acetylcholine receptor in complex with AT-1001
EMD-20488
Single-particle3.87 Å
Deposition: 19/07/2019Map released: 11/09/2019
Last modified: 20/11/2024
Sample Organism:
Homo sapiens,
Mus musculus
Sample: Human alpha3beta4 nicotinic receptor in complex with Fab fragments and bound to AT-1001
Fitted models: 6pv8
Deposition Authors: Gharpure A
,
Teng J
Sample: Human alpha3beta4 nicotinic receptor in complex with Fab fragments and bound to AT-1001
Fitted models: 6pv8
Deposition Authors: Gharpure A
,
Teng J
Agonist Selectivity and Ion Permeation in the alpha 3 beta 4 Ganglionic Nicotinic Receptor.
Gharpure A
,
Teng J,
Zhuang Y
,
Noviello CM,
Walsh Jr RM
,
Cabuco R,
Howard RJ,
Zaveri NT
,
Lindahl E,
Hibbs RE
(2019) Neuron , 104 , 501
,
Teng J,
Zhuang Y
,
Noviello CM,
Walsh Jr RM
,
Cabuco R,
Howard RJ,
Zaveri NT
,
Lindahl E,
Hibbs RE
(2019) Neuron , 104 , 501
Grant Support:
- Welch Foundation: I-1812 (United States)
- National Institutes of Health/National Institute on Drug Abuse (NIH/NIDA): T32DA07290 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): T32GM008203 (United States)
- National Institutes of Health/National Institute on Drug Abuse (NIH/NIDA): DA037492 (United States)
- National Institutes of Health/National Institute on Drug Abuse (NIH/NIDA): DA042072 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): NS095899 (United States)
