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EMD-43413
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The structure of LSD1-CoREST-HDAC1 in complex with KBTBD4IPR310delinsTTYML
Release date: Nov. 27, 2024
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8vpq
Q-score: 0.491

Xie X, Zhang O, Yeo MJR, Lee C, Tao R, Harry SA, Payne NC, Nam E, Paul L, Li Y, Kwok HS, Jiang H, Mao H, Hadley JL, Lin H, Batts M, Gosavi PM, D'Angiolella V, Cole PA, Mazitschek R, Northcott PA, Zheng N, Liau BB

Nature (2025) 639 pp. 241-249 [ DOI: doi:10.1038/s41586-024-08533-3 Pubmed: 39939763 ]

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Filter By

Current Database

  • EMDB [1]

Current status

  • REL [1]

Sample type

  • Complex [1]
  • Ligand [1]
  • Protein [1]

Organism

  • Homo sapiens [1]

EM Method

  • Single-particle [1]

Resolution

  • ≥ 3Å and < 4Å [1]

Model molecular weight

  • 100-250 kDa [1]

Release Date

  • 2024 [1]

Author by name

  • Batts M [1]
  • Cole PA [1]
  • D Angiolella V [1]
  • Gosavi PM [1]
  • Hadley JL [1]
  • Harry SA [1]
  • Jiang H [1]
  • Kwok HS [1]
  • Lee C [1]
  • Li Y [1]
  • Liau B [1]
  • Liau BB [1]
  • Lin H [1]
  • Mao H [1]
  • Mazitschek R [1]
  • Nam E [1]
  • Northcott PA [1]
  • Paul L [1]
  • Payne NC [1]
  • Tao R [1]
  • Xie X [1]
  • Yeo MJR [1]
  • Zhang O [1]
  • Zheng N [1]

Author by ORCID

  • Jiang H [1]
  • Cole PA [1]
  • D'angiolella V [1]
  • Payne NC [1]
  • Gosavi PM [1]
  • Zheng N [1]
  • Mazitschek R [1]
  • Northcott PA [1]
  • Kwok HS [1]
  • Liau BB [1]
  • Lee C [1]
  • Zhang O [1]
  • Li Y [1]
  • Yeo MJR [1]
  • Xie X [1]
  • Hadley JL [1]
  • Paul L [1]
  • Batts M [1]

Journal

  • NATURE [1]

Microscope

  • TFS KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [1]

Film or detector model

  • GATAN K3 6K X 4K [1]

External links

  • AlphaFold DB [1]
  • ChEBI [1]
  • ChEMBL [1]
  • Complex Portal [1]
  • DrugBank [1]
  • Gene Ontology [1]
  • InterPro [1]
  • PDB [1]
  • PDBe-Kb [1]
  • Pfam [1]
  • UniProt [1]