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EMD-43413
The structure of LSD1-CoREST-HDAC1 in complex with KBTBD4IPR310delinsTTYML
EMD-43413
Single-particle3.3 Å
Deposition: 16/01/2024Map released: 27/11/2024
Last modified: 11/06/2025
Sample Organism:
Homo sapiens
Sample: LHC-K4TTYML
Fitted models: 8vpq
Deposition Authors: Xie X
,
Liau B,
Zheng N
Sample: LHC-K4TTYML
Fitted models: 8vpq
Deposition Authors: Xie X
,
Liau B,
Zheng N
Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutations.
Xie X ,
Zhang O ,
Yeo MJR ,
Lee C ,
Tao R,
Harry SA,
Payne NC ,
Nam E,
Paul L ,
Li Y ,
Kwok HS ,
Jiang H ,
Mao H,
Hadley JL ,
Lin H,
Batts M ,
Gosavi PM ,
D'Angiolella V ,
Cole PA ,
Mazitschek R ,
Northcott PA ,
Zheng N ,
Liau BB
(2025) Nature , 639 , 241 - 249
,
Zhang O ,
Yeo MJR ,
Lee C ,
Tao R,
Harry SA,
Payne NC ,
Nam E,
Paul L ,
Li Y ,
Kwok HS ,
Jiang H ,
Mao H,
Hadley JL ,
Lin H,
Batts M ,
Gosavi PM ,
D'Angiolella V ,
Cole PA ,
Mazitschek R ,
Northcott PA ,
Zheng N ,
Liau BB
(2025) Nature , 639 , 241 - 249
Grant Support:
- Howard Hughes Medical Institute (HHMI): (United States)