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sample_name:"GPCR complex"

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Current Database

  • EMDB [8]

Current status

  • REL [8]

Sample type

  • Complex [8]
  • Protein [8]
  • Ligand [4]

Organism

  • Homo sapiens [8]
  • Lama glama [3]
  • Oplophorus gracilirostris [2]
  • Mus musculus [1]

EM Method

  • Single-particle [8]

Resolution

  • ≥ 2Å and < 3Å [3]
  • ≥ 3Å and < 4Å [5]

Model molecular weight

  • 100-250 kDa [7]
  • 250-500 kDa [1]

Release Date

  • 2024 [4]
  • 2021 [1]
  • 2020 [3]

Author by name

  • Zhu X [4]
  • Belousoff MJ [3]
  • Christopoulos A [3]
  • Danev R [3]
  • Deganutti G [3]
  • Fletcher MM [3]
  • Furness SGB [3]
  • Hay DL [3]
  • Khoshouei M [3]
  • Koole C [3]
  • Liang YL [3]
  • Miller LJ [3]
  • Reynolds CA [3]
  • Sexton PM [3]
  • Wootten D [3]
  • Zhang X [3]
  • Chen J [2]
  • Duan Y [2]
  • Gu Q [2]
  • Guo C [2]
  • He Y [2]
  • Huang Z [2]
  • Jin L [2]
  • Ke J [2]
  • Kim WJ [2]
  • Li F [2]
  • Li FH [2]
  • Li Y [2]
  • Liu J [2]
  • Lu Y [2]
  • Lv H [2]
  • Lv Z [2]
  • Ma Z [2]
  • Qian Y [2]
  • Song J [2]
  • Sun X [2]
  • Tang W [2]
  • Tang WQ [2]
  • Tian X [2]
  • Wang J [2]
  • Wang JY [2]
  • Wang T [2]
  • Wang TX [2]
  • Xia R [2]
  • Xiong Y [2]
  • Xu F [2]
  • Xu Z [2]
  • Yin H [2]
  • Zhang A [2]
  • Zhang Z [2]
  • Griffin PR [1]
  • Hunt JF [1]
  • Izard T [1]
  • Laboute T [1]
  • Martemyanov KA [1]
  • Novick SJ [1]
  • Patil DN [1]
  • Qiu X [1]
  • Robinson CV [1]
  • Singh AK [1]
  • Singh S [1]
  • Strutzenberg TS [1]
  • Wu D [1]

Author by ORCID

  • Fletcher MM [3]
  • Furness SGB [3]
  • Deganutti G [3]
  • Reynolds CA [3]
  • Zhang X [3]
  • Belousoff MJ [3]
  • Hay DL [3]
  • Wootten D [3]
  • He Y [2]
  • Ke J [2]
  • Kim WJ [2]
  • Wang J [2]
  • Huang Z [2]
  • Xu F [2]
  • Wang T [2]
  • Robinson CV [1]
  • Wu D [1]
  • Singh AK [1]
  • Izard T [1]
  • Griffin PR [1]
  • Martemyanov KA [1]
  • Hunt JF [1]
  • Novick SJ [1]
  • Singh S [1]
  • Strutzenberg TS [1]
  • Laboute T [1]
  • Patil DN [1]

Journal

  • ACS PHARMACOL TRANSL SCI [3]
  • CELL RES [2]
  • NAT COMMUN [2]
  • SCIENCE [1]

Software

  • CRYOSPARC [1]

Microscope

  • FEI TITAN KRIOS [8]

Electron Source

  • FIELD EMISSION GUN [8]

Film or detector model

  • GATAN K3 6K X 4K [4]
  • GATAN K2 SUMMIT 4K X 4K [2]
  • GATAN K3 BIOQUANTUM 6K X 4K [2]

External links

  • AlphaFold DB [8]
  • Gene Ontology [8]
  • InterPro [8]
  • PDB [8]
  • PDBe-Kb [8]
  • Pfam [8]
  • UniProt [8]
  • ChEBI [3]
  • ChEMBL [3]
  • Complex Portal [2]
  • DrugBank [2]
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Showing 1 - 8 of 8. Page 1 of 1
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EMD-37646
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3D View
Fzd4/DEP complex
Release date: Sept. 11, 2024
Resolution: 3.53 Å
EM Method: Single-particle
Fitted PDBs: 8wm9

Qian Y, Ma Z, Xu Z, Duan Y, Xiong Y, Xia R, Zhu X, Zhang Z, Tian X, Yin H, Liu J, Song J, Lu Y, Zhang A, Guo C, Jin L, Kim WJ, Ke J, Xu F, Huang Z, He Y

Nat Commun (2024) 15 pp. 7644-7644 [ DOI: doi:10.1038/s41467-024-52174-z Pubmed: 39223191 ]

EMD-37647
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3D View
Fzd4/DEP complex local refined
Release date: Sept. 11, 2024
Resolution: 3.47 Å
EM Method: Single-particle
Fitted PDBs: 8wma

Qian Y, Ma Z, Xu Z, Duan Y, Xiong Y, Xia R, Zhu X, Zhang Z, Tian X, Yin H, Liu J, Song J, Lu Y, Zhang A, Guo C, Jin L, Kim WJ, Ke J, Xu F, Huang Z, He Y

Nat Commun (2024) 15 pp. 7644-7644 [ DOI: doi:10.1038/s41467-024-52174-z Pubmed: 39223191 ]

EMD-36484
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Cryo-EM structure of succinate receptor bound to cis-epoxysuccinic acid coupling to Gi
Release date: May 22, 2024
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8jpn

Wang T, Tang W, Zhu X, Lv Z, Chen J, Li Y, Sun X, Lv H, Gu Q, Li F, Wang J

Cell Res (2024) 34 pp. 590-593 [ DOI: doi:10.1038/s41422-024-00968-7 Pubmed: 38744983 ]

EMD-36486
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Cryo-EM structure of succinate receptor bound to succinate acid coupling MiniGsq
Release date: May 22, 2024
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 8jpp

Wang T, Tang W, Zhu X, Lv Z, Chen J, Li Y, Sun X, Lv H, Gu Q, Li F, Wang J

Cell Res (2024) 34 pp. 590-593 [ DOI: doi:10.1038/s41422-024-00968-7 Pubmed: 38744983 ]

EMD-25126
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3D View
Cryo-EM structure of GPR158 coupled to the RGS7-Gbeta5 complex
Release date: Dec. 1, 2021
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7shf
Q-score: 0.478

Patil DN, Singh S, Laboute T, Strutzenberg TS, Qiu X, Wu D, Novick SJ, Robinson CV, Griffin PR, Hunt JF, Izard T, Singh AK, Martemyanov KA

Science (2022) 375 pp. 86-91 [ Pubmed: 34793198 DOI: doi:10.1126/science.abl4732 ]

EMD-20901
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CryoEM Structure of the active Adrenomedullin 2 receptor G protein complex with adrenomedullin peptide
Release date: April 1, 2020
Resolution: 2.4 Å
EM Method: Single-particle
Fitted PDBs: 6uus
Q-score: 0.535

Liang YL, Belousoff MJ, Fletcher MM, Zhang X, Khoshouei M, Deganutti G, Koole C, Furness SGB, Miller LJ, Hay DL, Christopoulos A, Reynolds CA, Danev R, Wootten D, Sexton PM

Acs Pharmacol Transl Sci (2020) 3 pp. 263-284 [ Pubmed: 32296767 DOI: doi:10.1021/acsptsci.9b00080 ]

EMD-20906
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CryoEM Structure of the active Adrenomedullin 2 receptor G protein complex with adrenomedullin 2 peptide
Release date: April 1, 2020
Resolution: 2.3 Å
EM Method: Single-particle
Fitted PDBs: 6uva
Q-score: 0.553

Liang YL, Belousoff MJ, Fletcher MM, Zhang X, Khoshouei M, Deganutti G, Koole C, Furness SGB, Miller LJ, Hay DL, Christopoulos A, Reynolds CA, Danev R, Wootten D, Sexton PM

Acs Pharmacol Transl Sci (2020) 3 pp. 263-284 [ Pubmed: 32296767 DOI: doi:10.1021/acsptsci.9b00080 ]

EMD-20883
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3D View
CryoEM Structure of the active Adrenomedullin 1 receptor G protein complex with adrenomedullin peptide
Release date: March 25, 2020
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6uun
Q-score: 0.48

Liang YL, Belousoff MJ, Fletcher MM, Zhang X, Khoshouei M, Deganutti G, Koole C, Furness SGB, Miller LJ, Hay DL, Christopoulos A, Reynolds CA, Danev R, Wootten D, Sexton PM

Acs Pharmacol Transl Sci (2020) 3 pp. 263-284 [ Pubmed: 32296767 DOI: doi:10.1021/acsptsci.9b00080 ]

Sort by: Download
Showing 1 - 8 of 8. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [8]

Current status

  • REL [8]

Sample type

  • Complex [8]
  • Protein [8]
  • Ligand [4]

Organism

  • Homo sapiens [8]
  • Lama glama [3]
  • Oplophorus gracilirostris [2]
  • Mus musculus [1]

EM Method

  • Single-particle [8]

Resolution

  • ≥ 2Å and < 3Å [3]
  • ≥ 3Å and < 4Å [5]

Model molecular weight

  • 100-250 kDa [7]
  • 250-500 kDa [1]

Release Date

  • 2024 [4]
  • 2021 [1]
  • 2020 [3]

Author by name

  • Zhu X [4]
  • Belousoff MJ [3]
  • Christopoulos A [3]
  • Danev R [3]
  • Deganutti G [3]
  • Fletcher MM [3]
  • Furness SGB [3]
  • Hay DL [3]
  • Khoshouei M [3]
  • Koole C [3]
  • Liang YL [3]
  • Miller LJ [3]
  • Reynolds CA [3]
  • Sexton PM [3]
  • Wootten D [3]
  • Zhang X [3]
  • Chen J [2]
  • Duan Y [2]
  • Gu Q [2]
  • Guo C [2]
  • He Y [2]
  • Huang Z [2]
  • Jin L [2]
  • Ke J [2]
  • Kim WJ [2]
  • Li F [2]
  • Li FH [2]
  • Li Y [2]
  • Liu J [2]
  • Lu Y [2]
  • Lv H [2]
  • Lv Z [2]
  • Ma Z [2]
  • Qian Y [2]
  • Song J [2]
  • Sun X [2]
  • Tang W [2]
  • Tang WQ [2]
  • Tian X [2]
  • Wang J [2]
  • Wang JY [2]
  • Wang T [2]
  • Wang TX [2]
  • Xia R [2]
  • Xiong Y [2]
  • Xu F [2]
  • Xu Z [2]
  • Yin H [2]
  • Zhang A [2]
  • Zhang Z [2]
  • Griffin PR [1]
  • Hunt JF [1]
  • Izard T [1]
  • Laboute T [1]
  • Martemyanov KA [1]
  • Novick SJ [1]
  • Patil DN [1]
  • Qiu X [1]
  • Robinson CV [1]
  • Singh AK [1]
  • Singh S [1]
  • Strutzenberg TS [1]
  • Wu D [1]

Author by ORCID

  • Fletcher MM [3]
  • Furness SGB [3]
  • Deganutti G [3]
  • Reynolds CA [3]
  • Zhang X [3]
  • Belousoff MJ [3]
  • Hay DL [3]
  • Wootten D [3]
  • He Y [2]
  • Ke J [2]
  • Kim WJ [2]
  • Wang J [2]
  • Huang Z [2]
  • Xu F [2]
  • Wang T [2]
  • Robinson CV [1]
  • Wu D [1]
  • Singh AK [1]
  • Izard T [1]
  • Griffin PR [1]
  • Martemyanov KA [1]
  • Hunt JF [1]
  • Novick SJ [1]
  • Singh S [1]
  • Strutzenberg TS [1]
  • Laboute T [1]
  • Patil DN [1]

Journal

  • ACS PHARMACOL TRANSL SCI [3]
  • CELL RES [2]
  • NAT COMMUN [2]
  • SCIENCE [1]

Software

  • CRYOSPARC [1]

Microscope

  • FEI TITAN KRIOS [8]

Electron Source

  • FIELD EMISSION GUN [8]

Film or detector model

  • GATAN K3 6K X 4K [4]
  • GATAN K2 SUMMIT 4K X 4K [2]
  • GATAN K3 BIOQUANTUM 6K X 4K [2]

External links

  • AlphaFold DB [8]
  • Gene Ontology [8]
  • InterPro [8]
  • PDB [8]
  • PDBe-Kb [8]
  • Pfam [8]
  • UniProt [8]
  • ChEBI [3]
  • ChEMBL [3]
  • Complex Portal [2]
  • DrugBank [2]