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sample_name:"DRD2 in complex mini-GoA"

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EM Method

  • Single-particle [2]

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  • ≥ 2Å and < 3Å [2]

Model molecular weight

  • 50-100 kDa [1]
  • 100-250 kDa [1]

Release Date

  • 2025 [2]

Author by name

  • Deleon C [2]
  • Diberto JF [2]
  • Dror RO [2]
  • Fay JF [2]
  • Gloriam DE [2]
  • Gumpper RH [2]
  • Hauser AS [2]
  • Huang XP [2]
  • Jain MK [2]
  • Keiser M [2]
  • Kim K [2]
  • Krumm BE [2]
  • Madsen JS [2]
  • Nichols DE [2]
  • Roth BL [2]
  • Schmitz GP [2]
  • Shoichet B [2]
  • Shub L [2]
  • Slocum ST [2]
  • Suomivuori CM [2]
  • Tummino TA [2]

Author by ORCID

  • Madsen JS [2]
  • Gloriam DE [2]
  • Dror RO [2]

Journal

  • NEURON [2]

Microscope

  • FEI TALOS ARCTICA [2]

Electron Source

  • FIELD EMISSION GUN [2]

Film or detector model

  • GATAN K3 6K X 4K [2]

External links

  • AlphaFold DB [2]
  • ChEBI [2]
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  • Gene Ontology [2]
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  • Pfam [2]
  • UniProt [2]
  • Complex Portal [1]
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EMD-44865
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Local refinement of DRD2 bound to LSD in complex with a mini-GoA and scFv16 obtained by cryo-electron microscopy cryoEM
Release date: Sept. 17, 2025
Resolution: 2.28 Å
EM Method: Single-particle
Fitted PDBs: 9bs9
Q-score: 0.597

Jain MK, Gumpper RH, Slocum ST, Schmitz GP, Madsen JS, Tummino TA, Suomivuori CM, Huang XP, Shub L, DiBerto JF, Kim K, DeLeon C, Krumm BE, Fay JF, Keiser M, Hauser AS, Dror RO, Shoichet B, Gloriam DE, Nichols DE, Roth BL

Neuron (2025) 113 pp. 3129-3142.e9 [ Pubmed: 40683247 DOI: doi:10.1016/j.neuron.2025.06.012 ]

EMD-44866
Download Map
3D View
Global reconstruction of DRD2 bound to LSD in complex with a mini-GoA and scFv16 obtained by cryo-electron microscopy cryoEM
Release date: Sept. 17, 2025
Resolution: 2.32 Å
EM Method: Single-particle
Fitted PDBs: 9bsb
Q-score: 0.607

Jain MK, Gumpper RH, Slocum ST, Schmitz GP, Madsen JS, Tummino TA, Suomivuori CM, Huang XP, Shub L, DiBerto JF, Kim K, DeLeon C, Krumm BE, Fay JF, Keiser M, Hauser AS, Dror RO, Shoichet B, Gloriam DE, Nichols DE, Roth BL

Neuron (2025) 113 pp. 3129-3142.e9 [ Pubmed: 40683247 DOI: doi:10.1016/j.neuron.2025.06.012 ]

Sort by: Download
Showing 1 - 2 of 2. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [2]

Current status

  • REL [2]

Sample type

  • Complex [2]
  • Ligand [2]
  • Protein [2]

Organism

  • Homo sapiens [2]
  • Mus musculus [1]

EM Method

  • Single-particle [2]

Resolution

  • ≥ 2Å and < 3Å [2]

Model molecular weight

  • 50-100 kDa [1]
  • 100-250 kDa [1]

Release Date

  • 2025 [2]

Author by name

  • Deleon C [2]
  • Diberto JF [2]
  • Dror RO [2]
  • Fay JF [2]
  • Gloriam DE [2]
  • Gumpper RH [2]
  • Hauser AS [2]
  • Huang XP [2]
  • Jain MK [2]
  • Keiser M [2]
  • Kim K [2]
  • Krumm BE [2]
  • Madsen JS [2]
  • Nichols DE [2]
  • Roth BL [2]
  • Schmitz GP [2]
  • Shoichet B [2]
  • Shub L [2]
  • Slocum ST [2]
  • Suomivuori CM [2]
  • Tummino TA [2]

Author by ORCID

  • Madsen JS [2]
  • Gloriam DE [2]
  • Dror RO [2]

Journal

  • NEURON [2]

Microscope

  • FEI TALOS ARCTICA [2]

Electron Source

  • FIELD EMISSION GUN [2]

Film or detector model

  • GATAN K3 6K X 4K [2]

External links

  • AlphaFold DB [2]
  • ChEBI [2]
  • ChEMBL [2]
  • DrugBank [2]
  • Gene Ontology [2]
  • PDB [2]
  • PDBe-Kb [2]
  • Pfam [2]
  • UniProt [2]
  • Complex Portal [1]