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natural_source_ncbi_code:"1410628"

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Current Database

  • EMDB [16]

Current status

  • REL [16]

Sample type

  • Complex [16]
  • Protein [16]
  • RNA [13]
  • Ligand [9]
  • DNA [3]
  • Other [1]

Organism

  • Lachnospiraceae bacterium nd2006 [16]
  • Moraxella bovoculi [7]
  • Synthetic construct [2]
  • Escherichia coli [1]
  • Vibrio cholerae [1]

EM Method

  • Single-particle [16]

Resolution

  • ≥ 2Å and < 3Å [3]
  • ≥ 3Å and < 4Å [9]
  • ≥ 4Å and < 5Å [2]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 100-250 kDa [11]
  • 250-500 kDa [3]

Release Date

  • 2025 [2]
  • 2020 [6]
  • 2019 [8]

Author by name

  • Chang L [12]
  • Li Z [12]
  • Zhang H [12]
  • Daczkowski CM [6]
  • Gabel C [6]
  • Mesecar AD [6]
  • Xiao R [6]
  • Adler BA [2]
  • Al-shayeb B [2]
  • Arkin AP [2]
  • Cao F [2]
  • Cress BF [2]
  • Doudna JA [2]
  • Fellmann C [2]
  • Guo X [2]
  • Hammel M [2]
  • Hu M [2]
  • Knott GJ [2]
  • Lew RJ [2]
  • Liang F [2]
  • Liu JJ [2]
  • Lobba MJ [2]
  • Pei D [2]
  • Qi W [2]
  • Rosenberg DJ [2]
  • Shan Y [2]
  • Shen Y [2]
  • Thornton BW [2]
  • Tian T [2]
  • Wang X [2]
  • Wang Y [2]
  • Xie W [2]
  • Xu M [2]
  • Zhang B [2]
  • Zhang M [2]
  • Zhang MF [2]
  • Zhou X [2]

Author by ORCID

  • Zhang H [12]
  • Li Z [6]
  • Gabel C [6]
  • Xiao R [3]
  • Chang L [3]
  • Zhou X [2]
  • Rosenberg DJ [2]
  • Liang F [2]
  • Doudna JA [2]
  • Zhang M [2]
  • Xu M [2]
  • Cress BF [2]
  • Al-shayeb B [2]
  • Arkin AP [2]
  • Pei D [2]
  • Hammel M [2]
  • Adler BA [2]
  • Liu JJ [2]
  • Knott GJ [2]
  • Fellmann C [2]
  • Xie W [2]
  • Thornton BW [2]

Journal

  • CELL HOST MICROBE [6]
  • CELL RES [3]
  • NAT STRUCT MOL BIOL [3]
  • ACTA CRYSTALLOGR D STRUCT BIOL [2]
  • ELIFE [2]
  • NAT COMMUN [2]

Software

  • RELION [8]
  • CISTEM [3]

Microscope

  • FEI TITAN KRIOS [14]
  • FEI MORGAGNI [2]

Electron Source

  • FIELD EMISSION GUN [16]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [12]
  • GATAN K3 6K X 4K [3]
  • FEI FALCON IV 4K X 4K [2]

External links

  • PDB [14]
  • UniProt [11]
  • AlphaFold DB [9]
  • ChEBI [9]
  • DrugBank [9]
  • ChEMBL [5]
  • PDBe-Kb [4]
  • Pfam [3]
  • Gene Ontology [1]
  • InterPro [1]
Sort by: Download
Showing 1 - 10 of 16. Page 1 of 2
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EMD-62606
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3D View
Cas12a-PCPS-dark
Release date: July 16, 2025
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 9kwb
Q-score: 0.508

Hu M, Zhang B, Shan Y, Cao F, Wang Y, Qi W, Wang X, Shen Y, Guo X, Zhang M, Tian T, Xie W, Zhang M, Liang F, Pei D, Zhou X

Nat Commun (2025) 16 pp. 5939-5939 [ DOI: doi:10.1038/s41467-025-61094-5 Pubmed: 40593724 ]

EMD-62607
Download Map
3D View
Cas12a-PCPS-light
Release date: July 16, 2025
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9kwc
Q-score: 0.385

Hu M, Zhang B, Shan Y, Cao F, Wang Y, Qi W, Wang X, Shen Y, Guo X, Zhang M, Tian T, Xie W, Zhang M, Liang F, Pei D, Zhou X

Nat Commun (2025) 16 pp. 5939-5939 [ DOI: doi:10.1038/s41467-025-61094-5 Pubmed: 40593724 ]

EMD-20909
Download Map
3D View
Cryo-EM structure of VcCascade complex
Release date: Sept. 16, 2020
Resolution: 3.8 Å
EM Method: Single-particle

Li Z, Zhang H, Xiao R, Chang L

Cell Res (2020) 30 pp. 179-181 [ Pubmed: 31900425 DOI: doi:10.1038/s41422-019-0268-y ]

EMD-21541
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Cryo-EM structure of Cas12i E894A -crRNA-dsDNA complex
Release date: Sept. 16, 2020
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 6w5c
Q-score: 0.526

Zhang H, Li Z, Xiao R, Chang L

Nat Struct Mol Biol (2020) 27 pp. 1069-1076 [ Pubmed: 32895556 DOI: doi:10.1038/s41594-020-0499-0 ]

EMD-21551
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3D View
Cryo-EM structure of Cas12i-crRNA complex
Release date: Sept. 16, 2020
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6w62
Q-score: 0.349

Zhang H, Li Z, Xiao R, Chang L

Nat Struct Mol Biol (2020) 27 pp. 1069-1076 [ Pubmed: 32895556 DOI: doi:10.1038/s41594-020-0499-0 ]

EMD-21552
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3D View
Cryo-EM structure of Cas12i-crRNA-dsDNA complex in I1 state
Release date: Sept. 16, 2020
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 6w64
Q-score: 0.321

Zhang H, Li Z, Xiao R, Chang L

Nat Struct Mol Biol (2020) 27 pp. 1069-1076 [ Pubmed: 32895556 DOI: doi:10.1038/s41594-020-0499-0 ]

EMD-20908
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3D View
CryoEM structure of VcCascasde-TniQ complex
Release date: Jan. 29, 2020
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 6uvn
Q-score: 0.486

Li Z, Zhang H, Xiao R, Chang L

Cell Res (2020) 30 pp. 179-181 [ Pubmed: 31900425 DOI: doi:10.1038/s41422-019-0268-y ]

EMD-20910
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3D View
Cryo-EM structure of VcCascade-TniQ supercomplex
Release date: Jan. 29, 2020
Resolution: 6.3 Å
EM Method: Single-particle

Li Z, Zhang H, Xiao R, Chang L

Cell Res (2020) 30 pp. 179-181 [ Pubmed: 31900425 DOI: doi:10.1038/s41422-019-0268-y ]

EMD-20266
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Cryo-EM structure of LbCas12a-crRNA: AcrVA4 1:2 complex
Release date: Aug. 21, 2019
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 6p7m
Q-score: 0.549

Knott GJ, Cress BF, Liu JJ, Thornton BW, Lew RJ, Al-Shayeb B, Rosenberg DJ, Hammel M, Adler BA, Lobba MJ, Xu M, Arkin AP, Fellmann C, Doudna JA

eLife (2019) 8 [ Pubmed: 31397669 DOI: doi:10.7554/eLife.49110 ]

EMD-20267
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3D View
Cryo-EM structure of LbCas12a-crRNA: AcrVA4 2:2 complex
Release date: Aug. 21, 2019
Resolution: 4.9 Å
EM Method: Single-particle
Fitted PDBs: 6p7n
Q-score: 0.158

Knott GJ, Cress BF, Liu JJ, Thornton BW, Lew RJ, Al-Shayeb B, Rosenberg DJ, Hammel M, Adler BA, Lobba MJ, Xu M, Arkin AP, Fellmann C, Doudna JA

eLife (2019) 8 [ Pubmed: 31397669 DOI: doi:10.7554/eLife.49110 ]

Sort by: Download
Showing 1 - 10 of 16. Page 1 of 2
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [16]

Current status

  • REL [16]

Sample type

  • Complex [16]
  • Protein [16]
  • RNA [13]
  • Ligand [9]
  • DNA [3]
  • Other [1]

Organism

  • Lachnospiraceae bacterium nd2006 [16]
  • Moraxella bovoculi [7]
  • Synthetic construct [2]
  • Escherichia coli [1]
  • Vibrio cholerae [1]

EM Method

  • Single-particle [16]

Resolution

  • ≥ 2Å and < 3Å [3]
  • ≥ 3Å and < 4Å [9]
  • ≥ 4Å and < 5Å [2]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [1]

Model molecular weight

  • 100-250 kDa [11]
  • 250-500 kDa [3]

Release Date

  • 2025 [2]
  • 2020 [6]
  • 2019 [8]

Author by name

  • Chang L [12]
  • Li Z [12]
  • Zhang H [12]
  • Daczkowski CM [6]
  • Gabel C [6]
  • Mesecar AD [6]
  • Xiao R [6]
  • Adler BA [2]
  • Al-shayeb B [2]
  • Arkin AP [2]
  • Cao F [2]
  • Cress BF [2]
  • Doudna JA [2]
  • Fellmann C [2]
  • Guo X [2]
  • Hammel M [2]
  • Hu M [2]
  • Knott GJ [2]
  • Lew RJ [2]
  • Liang F [2]
  • Liu JJ [2]
  • Lobba MJ [2]
  • Pei D [2]
  • Qi W [2]
  • Rosenberg DJ [2]
  • Shan Y [2]
  • Shen Y [2]
  • Thornton BW [2]
  • Tian T [2]
  • Wang X [2]
  • Wang Y [2]
  • Xie W [2]
  • Xu M [2]
  • Zhang B [2]
  • Zhang M [2]
  • Zhang MF [2]
  • Zhou X [2]

Author by ORCID

  • Zhang H [12]
  • Li Z [6]
  • Gabel C [6]
  • Xiao R [3]
  • Chang L [3]
  • Zhou X [2]
  • Rosenberg DJ [2]
  • Liang F [2]
  • Doudna JA [2]
  • Zhang M [2]
  • Xu M [2]
  • Cress BF [2]
  • Al-shayeb B [2]
  • Arkin AP [2]
  • Pei D [2]
  • Hammel M [2]
  • Adler BA [2]
  • Liu JJ [2]
  • Knott GJ [2]
  • Fellmann C [2]
  • Xie W [2]
  • Thornton BW [2]

Journal

  • CELL HOST MICROBE [6]
  • CELL RES [3]
  • NAT STRUCT MOL BIOL [3]
  • ACTA CRYSTALLOGR D STRUCT BIOL [2]
  • ELIFE [2]
  • NAT COMMUN [2]

Software

  • RELION [8]
  • CISTEM [3]

Microscope

  • FEI TITAN KRIOS [14]
  • FEI MORGAGNI [2]

Electron Source

  • FIELD EMISSION GUN [16]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [12]
  • GATAN K3 6K X 4K [3]
  • FEI FALCON IV 4K X 4K [2]

External links

  • PDB [14]
  • UniProt [11]
  • AlphaFold DB [9]
  • ChEBI [9]
  • DrugBank [9]
  • ChEMBL [5]
  • PDBe-Kb [4]
  • Pfam [3]
  • Gene Ontology [1]
  • InterPro [1]