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EMD-20267

Single-particle
4.9 Å
EMD-20267
3D View Gallery
Deposition: 06/06/2019
Map released: 21/08/2019
Last modified: 16/08/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-20267
Download
3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6p7n summary report (pdf.gz) Map and 6p7n FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of LbCas12a-crRNA: AcrVA4 (2:2 complex)

EMD-20267

Single-particle
4.9 Å
EMD-20267
3D View Gallery
Deposition: 06/06/2019
Map released: 21/08/2019
Last modified: 16/08/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Lachnospiraceae bacterium ND2006, Moraxella bovoculi
Sample: LbCas12a-crRNA-AcrVA4 Complex (2:2, State I)
Fitted models: 6p7n

Deposition Authors: Knott GJ , Liu JJ
Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a.
Knott GJ , Cress BF , Liu JJ, Thornton BW , Lew RJ, Al-Shayeb B , Rosenberg DJ , Hammel M , Adler BA , Lobba MJ, Xu M , Arkin AP , Fellmann C , Doudna JA
(2019) eLife , 8
PUBMED: 31397669
DOI: doi:10.7554/eLife.49110
ISSN: 2050-084X
Grant Support: