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grant_code:"NIH Intramural Research Program"

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Current Database

  • EMDB [6]

Current status

  • REL [6]

Sample type

  • Complex [6]
  • Protein [6]
  • Ligand [4]

Organism

  • Homo sapiens [6]

EM Method

  • Single-particle [6]

Resolution

  • ≥ 2Å and < 3Å [3]
  • ≥ 3Å and < 4Å [3]

Model molecular weight

  • 100-250 kDa [1]
  • 250-500 kDa [3]

Release Date

  • 2025 [6]

Author by name

  • Bochtler M [6]
  • Czarnocki-cieciura M [6]
  • Gewartowska O [6]
  • Kanai T [6]
  • Lountos G [6]
  • Lountos GT [6]
  • Rathore I [6]
  • Skowronek K [6]
  • Slyvka A [6]
  • Wang Z [6]
  • Wlodawer A [6]
  • Yang R [6]

Author by ORCID

  • Czarnocki-cieciura M [6]
  • Bochtler M [6]
  • Skowronek K [6]
  • Slyvka A [6]
  • Wlodawer A [6]
  • Lountos GT [6]

Journal

  • PNAS [6]

Software

  • CRYOSPARC [6]

Microscope

  • FEI TALOS ARCTICA [6]

Electron Source

  • FIELD EMISSION GUN [6]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [6]

External links

  • AlphaFold DB [6]
  • UniProt [6]
  • ChEBI [4]
  • ChEMBL [4]
  • DrugBank [4]
  • Gene Ontology [4]
  • InterPro [4]
  • PDB [4]
  • Pfam [4]
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Showing 1 - 6 of 6. Page 1 of 1
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EMD-52121
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3D View
Cryo-EM structure of human CDADC1 inactive mutant E400A : trimer without a ligand
Release date: April 30, 2025
Resolution: 3.06 Å
EM Method: Single-particle
Fitted PDBs: 9hfq
Q-score: 0.638

Slyvka A, Rathore I, Yang R, Gewartowska O, Kanai T, Lountos GT, Skowronek K, Czarnocki-Cieciura M, Wlodawer A, Bochtler M

PNAS (2025) 122 pp. e2424245122-e2424245122 [ DOI: doi:10.1073/pnas.2424245122 Pubmed: 40324085 ]

EMD-52122
Download Map
3D View
Cryo-EM structure of human CDADC1 inactive mutant E400A : hexamer without a ligand
Release date: April 30, 2025
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 9hfr
Q-score: 0.556

Slyvka A, Rathore I, Yang R, Gewartowska O, Kanai T, Lountos GT, Skowronek K, Czarnocki-Cieciura M, Wlodawer A, Bochtler M

PNAS (2025) 122 pp. e2424245122-e2424245122 [ DOI: doi:10.1073/pnas.2424245122 Pubmed: 40324085 ]

EMD-52123
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3D View
Cryo-EM structure of human CDADC1 inactive mutant E400A : trimer in the presence of dCTP in solution not bound
Release date: April 30, 2025
Resolution: 3.08 Å
EM Method: Single-particle

Slyvka A, Rathore I, Yang R, Gewartowska O, Kanai T, Lountos GT, Skowronek K, Czarnocki-Cieciura M, Wlodawer A, Bochtler M

PNAS (2025) 122 pp. e2424245122-e2424245122 [ DOI: doi:10.1073/pnas.2424245122 Pubmed: 40324085 ]

EMD-52124
Download Map
3D View
Cryo-EM structure of human CDADC1 inactive mutant E400A : hexamer with dCTP bound in the active site
Release date: April 30, 2025
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 9hfs
Q-score: 0.689

Slyvka A, Rathore I, Yang R, Gewartowska O, Kanai T, Lountos GT, Skowronek K, Czarnocki-Cieciura M, Wlodawer A, Bochtler M

PNAS (2025) 122 pp. e2424245122-e2424245122 [ DOI: doi:10.1073/pnas.2424245122 Pubmed: 40324085 ]

EMD-52125
Download Map
3D View
Cryo-EM structure of human CDADC1 inactive mutant E400A : trimer in the presence of 5mdCTP in solution not bound
Release date: April 30, 2025
Resolution: 2.81 Å
EM Method: Single-particle

Slyvka A, Rathore I, Yang R, Gewartowska O, Kanai T, Lountos GT, Skowronek K, Czarnocki-Cieciura M, Wlodawer A, Bochtler M

PNAS (2025) 122 pp. e2424245122-e2424245122 [ DOI: doi:10.1073/pnas.2424245122 Pubmed: 40324085 ]

EMD-52126
Download Map
3D View
Cryo-EM structure of human CDADC1 inactive mutant E400A : hexamer with 5mdCTP bound in the active site
Release date: April 30, 2025
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 9hft
Q-score: 0.665

Slyvka A, Rathore I, Yang R, Gewartowska O, Kanai T, Lountos GT, Skowronek K, Czarnocki-Cieciura M, Wlodawer A, Bochtler M

PNAS (2025) 122 pp. e2424245122-e2424245122 [ DOI: doi:10.1073/pnas.2424245122 Pubmed: 40324085 ]

Sort by: Download
Showing 1 - 6 of 6. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [6]

Current status

  • REL [6]

Sample type

  • Complex [6]
  • Protein [6]
  • Ligand [4]

Organism

  • Homo sapiens [6]

EM Method

  • Single-particle [6]

Resolution

  • ≥ 2Å and < 3Å [3]
  • ≥ 3Å and < 4Å [3]

Model molecular weight

  • 100-250 kDa [1]
  • 250-500 kDa [3]

Release Date

  • 2025 [6]

Author by name

  • Bochtler M [6]
  • Czarnocki-cieciura M [6]
  • Gewartowska O [6]
  • Kanai T [6]
  • Lountos G [6]
  • Lountos GT [6]
  • Rathore I [6]
  • Skowronek K [6]
  • Slyvka A [6]
  • Wang Z [6]
  • Wlodawer A [6]
  • Yang R [6]

Author by ORCID

  • Czarnocki-cieciura M [6]
  • Bochtler M [6]
  • Skowronek K [6]
  • Slyvka A [6]
  • Wlodawer A [6]
  • Lountos GT [6]

Journal

  • PNAS [6]

Software

  • CRYOSPARC [6]

Microscope

  • FEI TALOS ARCTICA [6]

Electron Source

  • FIELD EMISSION GUN [6]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [6]

External links

  • AlphaFold DB [6]
  • UniProt [6]
  • ChEBI [4]
  • ChEMBL [4]
  • DrugBank [4]
  • Gene Ontology [4]
  • InterPro [4]
  • PDB [4]
  • Pfam [4]