EMD-52125
Cryo-EM structure of human CDADC1 inactive mutant (E400A): trimer in the presence of 5mdCTP in solution (not bound)
EMD-52125
Single-particle2.81 Å
Deposition: 18/11/2024Map released: 30/04/2025
Last modified: 21/05/2025
Sample Organism:
Homo sapiens
Sample: Human CDADC1 trimer without a ligand (solution with 5mdCTP)
Deposition Authors: Slyvka A
,
Rathore I ,
Yang R ,
Kanai T ,
Lountos G ,
Wang Z,
Skowronek K ,
Czarnocki-Cieciura M ,
Wlodawer A ,
Bochtler M
Sample: Human CDADC1 trimer without a ligand (solution with 5mdCTP)
Deposition Authors: Slyvka A
,
Rathore I ,
Yang R ,
Kanai T ,
Lountos G ,
Wang Z,
Skowronek K ,
Czarnocki-Cieciura M ,
Wlodawer A ,
Bochtler M
Activity and structure of human (d)CTP deaminase CDADC1.
Slyvka A ,
Rathore I ,
Yang R ,
Gewartowska O,
Kanai T ,
Lountos GT ,
Skowronek K ,
Czarnocki-Cieciura M ,
Wlodawer A ,
Bochtler M
(2025) PNAS , 122 , e2424245122 - e2424245122
,
Rathore I ,
Yang R ,
Gewartowska O,
Kanai T ,
Lountos GT ,
Skowronek K ,
Czarnocki-Cieciura M ,
Wlodawer A ,
Bochtler M
(2025) PNAS , 122 , e2424245122 - e2424245122
Grant Support:
- Foundation for Polish Science: POIR.04.04.00-00-5D81/17-00 (Poland)
- Ministry of Science and Higher Education (Poland): PPI/APM/2018/1/00034 (Poland)
- National Institutes of Health/National Cancer Institute (NIH/NCI): NIH Intramural Research Program (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): 75N91019D00024 (United States)