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grant_code:"GM007062"

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Current Database

  • EMDB [3]

Current status

  • REL [3]

Sample type

  • Complex [3]
  • Ligand [3]
  • Protein [3]

Organism

  • Plasmodium falciparum [3]

EM Method

  • Single-particle [3]

Resolution

  • ≥ 2Å and < 3Å [2]
  • ≥ 3Å and < 4Å [1]

Model molecular weight

  • 500-1000 kDa [3]

Release Date

  • 2025 [2]
  • 2024 [1]

Author by name

  • Campbell SF [3]
  • Charman SA [3]
  • Chen G [3]
  • Chen Z [3]
  • Deng X [3]
  • Gahalawat S [3]
  • Han Y [3]
  • Katneni K [3]
  • Laleu B [3]
  • Lawong A [3]
  • Phillips M [3]
  • Phillips MA [3]
  • Ray S [3]
  • Ready JM [3]
  • Saunders J [3]
  • Shackleford DM [3]
  • Zhang X [3]
  • C Maity B [2]
  • Collins D [2]
  • De N [2]
  • Hu M [2]
  • Jayaseelan J [2]
  • Li P [2]
  • Mcinerney M [2]
  • Ng A [2]
  • Noack CL [2]
  • Wang W [2]
  • Zhong L [2]
  • Angulo-barturen I [1]
  • Casas A [1]
  • Crighton E [1]
  • Fairhurst KJ [1]
  • Fidock DA [1]
  • Ho N [1]
  • Hosangadi V [1]
  • Imlay LS [1]
  • Jimenez-diaz MB [1]
  • Kumar A [1]
  • Lemoff A [1]
  • Liszczak G [1]
  • Robinson JJ [1]
  • Tashiro K [1]
  • Ward KE [1]
  • Wittlin S [1]
  • Xing C [1]
  • Zhao Z [1]

Author by ORCID

  • Laleu B [3]
  • Charman SA [3]
  • Phillips MA [2]
  • Ray S [2]
  • Ready JM [2]
  • Mcinerney M [2]
  • Xing C [1]
  • Lemoff A [1]
  • Robinson JJ [1]
  • Shackleford DM [1]

Journal

  • J MED CHEM [2]
  • CELL CHEM BIOL [1]

Software

  • GCTF [2]
  • RELION [2]
  • CRYOSPARC [1]

Microscope

  • TFS KRIOS [2]
  • FEI TITAN KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [3]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [2]
  • GATAN K3 BIOCONTINUUM 6K X 4K [1]

External links

  • AlphaFold DB [3]
  • Gene Ontology [3]
  • PDB [3]
  • PDBe-Kb [3]
  • Pfam [3]
  • UniProt [3]
  • InterPro [1]
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EMD-70077
Download Map
3D View
Plasmodium falciparum 20S proteasome bound to inhibitor 159
Release date: Nov. 12, 2025
Resolution: 2.79 Å
EM Method: Single-particle
Fitted PDBs: 9o3e
Q-score: 0.563

Gahalawat S, Ray S, Zhang X, Deng X, Han Y, Chen Z, Lawong A, Shackleford DM, Katneni K, Chen G, Li P, Ng A, Zhong L, Hu M, McInerney M, Wang W, Saunders J, Collins D, Jayaseelan J, Noack CL, C Maity B, De N, Laleu B, Campbell SF, Phillips MA, Charman SA, Ready JM

J Med Chem (2025) 68 pp. 23485-23520 [ Pubmed: 41148577 DOI: doi:10.1021/acs.jmedchem.5c02394 ]

EMD-70078
Download Map
3D View
Plasmodium falciparum 20S proteasome bound to inhibitor 296
Release date: Nov. 12, 2025
Resolution: 2.28 Å
EM Method: Single-particle
Fitted PDBs: 9o3f
Q-score: 0.694

Gahalawat S, Ray S, Zhang X, Deng X, Han Y, Chen Z, Lawong A, Shackleford DM, Katneni K, Chen G, Li P, Ng A, Zhong L, Hu M, McInerney M, Wang W, Saunders J, Collins D, Jayaseelan J, Noack CL, C Maity B, De N, Laleu B, Campbell SF, Phillips MA, Charman SA, Ready JM

J Med Chem (2025) 68 pp. 23485-23520 [ Pubmed: 41148577 DOI: doi:10.1021/acs.jmedchem.5c02394 ]

EMD-43746
Download Map
3D View
Plasmodium falciparum 20S proteasome bound to an inhibitor
Release date: July 31, 2024
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 8w2f
Q-score: 0.576

Lawong A, Gahalawat S, Ray S, Ho N, Han Y, Ward KE, Deng X, Chen Z, Kumar A, Xing C, Hosangadi V, Fairhurst KJ, Tashiro K, Liszczak G, Shackleford DM, Katneni K, Chen G, Saunders J, Crighton E, Casas A, Robinson JJ, Imlay LS, Zhang X, Lemoff A, Zhao Z, Angulo-Barturen I, Jimenez-Diaz MB, Wittlin S, Campbell SF, Fidock DA, Laleu B, Charman SA, Ready JM, Phillips MA

Cell Chem Biol (2024) 31 pp. 1503- [ DOI: doi:10.1016/j.chembiol.2024.07.001 Pubmed: 39084225 ]

Sort by: Download
Showing 1 - 3 of 3. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [3]

Current status

  • REL [3]

Sample type

  • Complex [3]
  • Ligand [3]
  • Protein [3]

Organism

  • Plasmodium falciparum [3]

EM Method

  • Single-particle [3]

Resolution

  • ≥ 2Å and < 3Å [2]
  • ≥ 3Å and < 4Å [1]

Model molecular weight

  • 500-1000 kDa [3]

Release Date

  • 2025 [2]
  • 2024 [1]

Author by name

  • Campbell SF [3]
  • Charman SA [3]
  • Chen G [3]
  • Chen Z [3]
  • Deng X [3]
  • Gahalawat S [3]
  • Han Y [3]
  • Katneni K [3]
  • Laleu B [3]
  • Lawong A [3]
  • Phillips M [3]
  • Phillips MA [3]
  • Ray S [3]
  • Ready JM [3]
  • Saunders J [3]
  • Shackleford DM [3]
  • Zhang X [3]
  • C Maity B [2]
  • Collins D [2]
  • De N [2]
  • Hu M [2]
  • Jayaseelan J [2]
  • Li P [2]
  • Mcinerney M [2]
  • Ng A [2]
  • Noack CL [2]
  • Wang W [2]
  • Zhong L [2]
  • Angulo-barturen I [1]
  • Casas A [1]
  • Crighton E [1]
  • Fairhurst KJ [1]
  • Fidock DA [1]
  • Ho N [1]
  • Hosangadi V [1]
  • Imlay LS [1]
  • Jimenez-diaz MB [1]
  • Kumar A [1]
  • Lemoff A [1]
  • Liszczak G [1]
  • Robinson JJ [1]
  • Tashiro K [1]
  • Ward KE [1]
  • Wittlin S [1]
  • Xing C [1]
  • Zhao Z [1]

Author by ORCID

  • Laleu B [3]
  • Charman SA [3]
  • Phillips MA [2]
  • Ray S [2]
  • Ready JM [2]
  • Mcinerney M [2]
  • Xing C [1]
  • Lemoff A [1]
  • Robinson JJ [1]
  • Shackleford DM [1]

Journal

  • J MED CHEM [2]
  • CELL CHEM BIOL [1]

Software

  • GCTF [2]
  • RELION [2]
  • CRYOSPARC [1]

Microscope

  • TFS KRIOS [2]
  • FEI TITAN KRIOS [1]

Electron Source

  • FIELD EMISSION GUN [3]

Film or detector model

  • GATAN K3 BIOQUANTUM 6K X 4K [2]
  • GATAN K3 BIOCONTINUUM 6K X 4K [1]

External links

  • AlphaFold DB [3]
  • Gene Ontology [3]
  • PDB [3]
  • PDBe-Kb [3]
  • Pfam [3]
  • UniProt [3]
  • InterPro [1]