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grant_code:"DGE-1747503"

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Current Database

  • EMDB [5]

Current status

  • REL [5]

Sample type

  • Complex [5]
  • Protein [5]

Organism

  • Homo sapiens [5]
  • Lama glama [4]
  • Synthetic construct [2]

EM Method

  • Single-particle [5]

Resolution

  • ≥ 2Å and < 3Å [2]
  • ≥ 3Å and < 4Å [3]

Model molecular weight

  • 100-250 kDa [5]

Release Date

  • 2025 [3]
  • 2022 [2]

Author by name

  • Belousoff MJ [5]
  • Cary BP [5]
  • Deganutti G [5]
  • Gellman SH [5]
  • Sexton PM [5]
  • Wootten D [5]
  • Hager MV [3]
  • Mariam Z [3]
  • Morris RK [3]
  • Danev R [2]
  • Liu X [2]
  • Piper SJ [2]
  • Truong TT [2]
  • Zhao P [2]

Author by ORCID

  • Gellman SH [5]
  • Deganutti G [5]
  • Sexton PM [5]
  • Cary BP [5]
  • Piper SJ [2]
  • Danev R [2]
  • Belousoff MJ [2]
  • Liu X [2]
  • Wootten D [2]

Journal

  • PNAS [3]
  • NAT CHEM BIOL [2]
  • BIORXIV [1]

Software

  • CRYOSPARC [3]
  • RELION [1]

Microscope

  • TFS GLACIOS [3]
  • FEI TITAN KRIOS [2]

Electron Source

  • FIELD EMISSION GUN [5]

Film or detector model

  • FEI FALCON IV 4K X 4K [3]
  • GATAN K3 BIOQUANTUM 6K X 4K [2]

External links

  • AlphaFold DB [5]
  • Gene Ontology [5]
  • InterPro [5]
  • PDB [5]
  • PDBe-Kb [5]
  • Pfam [5]
  • UniProt [5]
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EMD-47882
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3D View
Peptide 1 GLP-1 Aib16, ACPC18 bound to GLP-1R/Gs complex
Release date: March 26, 2025
Resolution: 3.44 Å
EM Method: Single-particle
Fitted PDBs: 9ebn
Q-score: 0.44

Cary BP, Hager MV, Mariam Z, Morris RK, Belousoff MJ, Deganutti G, Sexton PM, Wootten D, Gellman SH

PNAS (2025) 122 pp. e2407574122-e2407574122 [ Pubmed: 40168114 DOI: doi:10.1073/pnas.2407574122 ]

EMD-47883
Download Map
3D View
Peptide 2 GLP-1 ACPC18 bound to GLP-1R/Gs complex conformer 1
Release date: March 26, 2025
Resolution: 3.13 Å
EM Method: Single-particle
Fitted PDBs: 9ebo
Q-score: 0.447

Cary BP, Hager MV, Mariam Z, Morris RK, Belousoff MJ, Deganutti G, Sexton PM, Wootten D, Gellman SH

PNAS (2025) 122 pp. e2407574122-e2407574122 [ Pubmed: 40168114 DOI: doi:10.1073/pnas.2407574122 ]

EMD-47884
Download Map
3D View
Peptide 2 GLP-1 ACPC18 bound to GLP-1R/Gs complex conformer 2
Release date: March 26, 2025
Resolution: 3.16 Å
EM Method: Single-particle
Fitted PDBs: 9ebq
Q-score: 0.44

Cary BP, Hager MV, Mariam Z, Morris RK, Belousoff MJ, Deganutti G, Sexton PM, Wootten D, Gellman SH

PNAS (2025) 122 pp. e2407574122-e2407574122 [ Pubmed: 40168114 DOI: doi:10.1073/pnas.2407574122 ]

EMD-24805
Download Map
3D View
Ex4-D-Ala bound to the glucagon-like peptide-1 receptor/g protein complex conformer 1
Release date: Jan. 5, 2022
Resolution: 2.41 Å
EM Method: Single-particle
Fitted PDBs: 7s1m
Q-score: 0.581

Cary BP, Deganutti G, Zhao P, Truong TT, Piper SJ, Liu X, Belousoff MJ, Danev R, Sexton PM, Wootten D, Gellman SH

Nat Chem Biol (2022) 18 pp. 256-263 [ DOI: doi:10.1038/s41589-021-00945-w Pubmed: 34937906 ]

EMD-24825
Download Map
3D View
Ex4-D-Ala bound to the glucagon-like peptide-1 receptor/g protein complex conformer 2
Release date: Jan. 5, 2022
Resolution: 2.51 Å
EM Method: Single-particle
Fitted PDBs: 7s3i
Q-score: 0.58

Cary BP, Deganutti G, Zhao P, Truong TT, Piper SJ, Liu X, Belousoff MJ, Danev R, Sexton PM, Wootten D, Gellman SH

Nat Chem Biol (2022) 18 pp. 256-263 [ DOI: doi:10.1038/s41589-021-00945-w Pubmed: 34937906 ]

Sort by: Download
Showing 1 - 5 of 5. Page 1 of 1
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [5]

Current status

  • REL [5]

Sample type

  • Complex [5]
  • Protein [5]

Organism

  • Homo sapiens [5]
  • Lama glama [4]
  • Synthetic construct [2]

EM Method

  • Single-particle [5]

Resolution

  • ≥ 2Å and < 3Å [2]
  • ≥ 3Å and < 4Å [3]

Model molecular weight

  • 100-250 kDa [5]

Release Date

  • 2025 [3]
  • 2022 [2]

Author by name

  • Belousoff MJ [5]
  • Cary BP [5]
  • Deganutti G [5]
  • Gellman SH [5]
  • Sexton PM [5]
  • Wootten D [5]
  • Hager MV [3]
  • Mariam Z [3]
  • Morris RK [3]
  • Danev R [2]
  • Liu X [2]
  • Piper SJ [2]
  • Truong TT [2]
  • Zhao P [2]

Author by ORCID

  • Gellman SH [5]
  • Deganutti G [5]
  • Sexton PM [5]
  • Cary BP [5]
  • Piper SJ [2]
  • Danev R [2]
  • Belousoff MJ [2]
  • Liu X [2]
  • Wootten D [2]

Journal

  • PNAS [3]
  • NAT CHEM BIOL [2]
  • BIORXIV [1]

Software

  • CRYOSPARC [3]
  • RELION [1]

Microscope

  • TFS GLACIOS [3]
  • FEI TITAN KRIOS [2]

Electron Source

  • FIELD EMISSION GUN [5]

Film or detector model

  • FEI FALCON IV 4K X 4K [3]
  • GATAN K3 BIOQUANTUM 6K X 4K [2]

External links

  • AlphaFold DB [5]
  • Gene Ontology [5]
  • InterPro [5]
  • PDB [5]
  • PDBe-Kb [5]
  • Pfam [5]
  • UniProt [5]