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EMD-24805

Single-particle
2.41 Å
EMD-24805
3D View Gallery
Deposition: 02/09/2021
Map released: 05/01/2022
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-24805
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7s1m summary report (pdf.gz) Map and 7s1m FULL report (pdf.gz)
EMICSS annotations (xml)

Ex4-D-Ala bound to the glucagon-like peptide-1 receptor/g protein complex (conformer 1)

EMD-24805

Single-particle
2.41 Å
EMD-24805
3D View Gallery
Deposition: 02/09/2021
Map released: 05/01/2022
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Lama glama, synthetic construct
Sample: GLP-1R bound to Ex4-D-Ala, G alpha s, G beta-1, G gamma-2, and Nb35
Fitted models: 7s1m

Deposition Authors: Cary BP , Gellman SH
Structural and functional diversity among agonist-bound states of the GLP-1 receptor.
Cary BP , Deganutti G , Zhao P, Truong TT, Piper SJ , Liu X , Belousoff MJ , Danev R , Sexton PM , Wootten D , Gellman SH
(2022) Nat Chem Biol , 18 , 256 - 263
PUBMED: 34937906
DOI: doi:10.1038/s41589-021-00945-w
ISSN: 1552-4469