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grant_code:"CA206573"

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Current Database

  • EMDB [35]

Current status

  • REL [35]

Sample type

  • Complex [35]
  • Protein [35]
  • Ligand [33]

Organism

  • Rattus norvegicus [35]
  • Homo sapiens [10]
  • Mus musculus [5]

EM Method

  • Single-particle [35]

Resolution

  • ≥ 2Å and < 3Å [3]
  • ≥ 3Å and < 4Å [13]
  • ≥ 4Å and < 5Å [16]
  • ≥ 6Å and < 8Å [3]

Model molecular weight

  • 250-500 kDa [26]
  • 500-1000 kDa [9]

Release Date

  • 2023 [10]
  • 2022 [7]
  • 2021 [9]
  • 2018 [3]
  • 2017 [6]

Author by name

  • Sobolevsky AI [35]
  • Yelshanskaya MV [35]
  • Gangwar SP [19]
  • Jones DR [10]
  • Korman A [10]
  • Yen LY [10]
  • Klykov O [9]
  • Klykov OV [9]
  • Twomey EC [9]
  • Yen L [9]
  • Kottke CM [7]
  • Kurnikova MG [7]
  • Patel DS [7]
  • Frank J [6]
  • Grassucci RA [6]
  • Vassilevski AA [3]

Author by ORCID

  • Gangwar SP [19]
  • Sobolevsky AI [17]
  • Jones DR [10]
  • Korman A [10]
  • Twomey EC [9]
  • Yen L [9]
  • Klykov O [9]
  • Kurnikova MG [7]
  • Vassilevski AA [3]

Journal

  • NATURE [12]
  • NAT STRUCT MOL BIOL [10]
  • MOL CELL [9]
  • NEURON [4]

Software

  • CRYOSPARC [9]
  • RELION [9]
  • COOT [6]

Microscope

  • FEI TITAN KRIOS [31]
  • FEI POLARA 300 [4]

Electron Source

  • FIELD EMISSION GUN [35]

Film or detector model

  • GATAN K3 6K X 4K [22]
  • GATAN K2 SUMMIT 4K X 4K [9]
  • FEI FALCON IV 4K X 4K [4]

External links

  • AlphaFold DB [35]
  • Gene Ontology [35]
  • InterPro [35]
  • PDB [35]
  • PDBe-Kb [35]
  • Pfam [35]
  • UniProt [35]
  • ChEBI [31]
  • DrugBank [31]
  • ChEMBL [30]
  • Complex Portal [14]
  • SCOP2 [2]
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Showing 1 - 10 of 35. Page 1 of 4
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EMD-40741
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3D View
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK and channel blocker spermidine closed state
Release date: Sept. 6, 2023
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 8ss2
Q-score: 0.438

Gangwar SP, Yen LY, Yelshanskaya MV, Korman A, Jones DR, Sobolevsky AI

Nat Struct Mol Biol (2023) 30 pp. 1481-1494 [ DOI: doi:10.1038/s41594-023-01080-x Pubmed: 37653241 ]

EMD-40742
Download Map
3D View
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK and channel blocker spermidine closed state
Release date: Sept. 6, 2023
Resolution: 3.21 Å
EM Method: Single-particle
Fitted PDBs: 8ss3
Q-score: 0.507

Gangwar SP, Yen LY, Yelshanskaya MV, Korman A, Jones DR, Sobolevsky AI

Nat Struct Mol Biol (2023) 30 pp. 1481-1494 [ DOI: doi:10.1038/s41594-023-01080-x Pubmed: 37653241 ]

EMD-40743
Download Map
3D View
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 apo state
Release date: Sept. 6, 2023
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 8ss4
Q-score: 0.469

Gangwar SP, Yen LY, Yelshanskaya MV, Korman A, Jones DR, Sobolevsky AI

Nat Struct Mol Biol (2023) 30 pp. 1481-1494 [ DOI: doi:10.1038/s41594-023-01080-x Pubmed: 37653241 ]

EMD-40744
Download Map
3D View
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 apo state
Release date: Sept. 6, 2023
Resolution: 3.56 Å
EM Method: Single-particle
Fitted PDBs: 8ss5
Q-score: 0.4

Gangwar SP, Yen LY, Yelshanskaya MV, Korman A, Jones DR, Sobolevsky AI

Nat Struct Mol Biol (2023) 30 pp. 1481-1494 [ DOI: doi:10.1038/s41594-023-01080-x Pubmed: 37653241 ]

EMD-40745
Download Map
3D View
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK, channel blocker spermidine and antiepileptic drug perampanel closed state
Release date: Sept. 6, 2023
Resolution: 3.01 Å
EM Method: Single-particle
Fitted PDBs: 8ss6
Q-score: 0.475

Gangwar SP, Yen LY, Yelshanskaya MV, Korman A, Jones DR, Sobolevsky AI

Nat Struct Mol Biol (2023) 30 pp. 1481-1494 [ DOI: doi:10.1038/s41594-023-01080-x Pubmed: 37653241 ]

EMD-40746
Download Map
3D View
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK, channel blocker spermidine and antiepileptic drug perampanel closed state
Release date: Sept. 6, 2023
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 8ss7
Q-score: 0.544

Gangwar SP, Yen LY, Yelshanskaya MV, Korman A, Jones DR, Sobolevsky AI

Nat Struct Mol Biol (2023) 30 pp. 1481-1494 [ DOI: doi:10.1038/s41594-023-01080-x Pubmed: 37653241 ]

EMD-40747
Download Map
3D View
Structure of AMPA receptor GluA2 complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel closed state
Release date: Sept. 6, 2023
Resolution: 2.81 Å
EM Method: Single-particle
Fitted PDBs: 8ss8
Q-score: 0.53

Gangwar SP, Yen LY, Yelshanskaya MV, Korman A, Jones DR, Sobolevsky AI

Nat Struct Mol Biol (2023) 30 pp. 1481-1494 [ DOI: doi:10.1038/s41594-023-01080-x Pubmed: 37653241 ]

EMD-40748
Download Map
3D View
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel closed state
Release date: Sept. 6, 2023
Resolution: 2.72 Å
EM Method: Single-particle
Fitted PDBs: 8ss9
Q-score: 0.519

Gangwar SP, Yen LY, Yelshanskaya MV, Korman A, Jones DR, Sobolevsky AI

Nat Struct Mol Biol (2023) 30 pp. 1481-1494 [ DOI: doi:10.1038/s41594-023-01080-x Pubmed: 37653241 ]

EMD-40749
Download Map
3D View
Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to glutamate and channel blocker spermidine desensitized state
Release date: Sept. 6, 2023
Resolution: 3.88 Å
EM Method: Single-particle
Fitted PDBs: 8ssa
Q-score: 0.325

Gangwar SP, Yen LY, Yelshanskaya MV, Korman A, Jones DR, Sobolevsky AI

Nat Struct Mol Biol (2023) 30 pp. 1481-1494 [ DOI: doi:10.1038/s41594-023-01080-x Pubmed: 37653241 ]

EMD-40750
Download Map
3D View
Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to glutamate and channel blocker spermidine desensitized state
Release date: Sept. 6, 2023
Resolution: 3.66 Å
EM Method: Single-particle
Fitted PDBs: 8ssb
Q-score: 0.382

Gangwar SP, Yen LY, Yelshanskaya MV, Korman A, Jones DR, Sobolevsky AI

Nat Struct Mol Biol (2023) 30 pp. 1481-1494 [ DOI: doi:10.1038/s41594-023-01080-x Pubmed: 37653241 ]

Sort by: Download
Showing 1 - 10 of 35. Page 1 of 4
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [35]

Current status

  • REL [35]

Sample type

  • Complex [35]
  • Protein [35]
  • Ligand [33]

Organism

  • Rattus norvegicus [35]
  • Homo sapiens [10]
  • Mus musculus [5]

EM Method

  • Single-particle [35]

Resolution

  • ≥ 2Å and < 3Å [3]
  • ≥ 3Å and < 4Å [13]
  • ≥ 4Å and < 5Å [16]
  • ≥ 6Å and < 8Å [3]

Model molecular weight

  • 250-500 kDa [26]
  • 500-1000 kDa [9]

Release Date

  • 2023 [10]
  • 2022 [7]
  • 2021 [9]
  • 2018 [3]
  • 2017 [6]

Author by name

  • Sobolevsky AI [35]
  • Yelshanskaya MV [35]
  • Gangwar SP [19]
  • Jones DR [10]
  • Korman A [10]
  • Yen LY [10]
  • Klykov O [9]
  • Klykov OV [9]
  • Twomey EC [9]
  • Yen L [9]
  • Kottke CM [7]
  • Kurnikova MG [7]
  • Patel DS [7]
  • Frank J [6]
  • Grassucci RA [6]
  • Vassilevski AA [3]

Author by ORCID

  • Gangwar SP [19]
  • Sobolevsky AI [17]
  • Jones DR [10]
  • Korman A [10]
  • Twomey EC [9]
  • Yen L [9]
  • Klykov O [9]
  • Kurnikova MG [7]
  • Vassilevski AA [3]

Journal

  • NATURE [12]
  • NAT STRUCT MOL BIOL [10]
  • MOL CELL [9]
  • NEURON [4]

Software

  • CRYOSPARC [9]
  • RELION [9]
  • COOT [6]

Microscope

  • FEI TITAN KRIOS [31]
  • FEI POLARA 300 [4]

Electron Source

  • FIELD EMISSION GUN [35]

Film or detector model

  • GATAN K3 6K X 4K [22]
  • GATAN K2 SUMMIT 4K X 4K [9]
  • FEI FALCON IV 4K X 4K [4]

External links

  • AlphaFold DB [35]
  • Gene Ontology [35]
  • InterPro [35]
  • PDB [35]
  • PDBe-Kb [35]
  • Pfam [35]
  • UniProt [35]
  • ChEBI [31]
  • DrugBank [31]
  • ChEMBL [30]
  • Complex Portal [14]
  • SCOP2 [2]