Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

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grant_code:"AI170855"

Filter By

Current Database

  • EMDB [60]

Current status

  • REL [60]

Sample type

  • Complex [60]
  • Protein [3]
  • DNA [1]
  • Ligand [1]

Organism

  • Escherichia coli [36]
  • Escherichia coli [18]
  • Human immunodeficiency virus 1 [6]
  • Human immunodeficiency virus 1 [3]
  • Homo sapiens [1]

EM Method

  • Single-particle [60]

Resolution

  • ≥ 3Å and < 4Å [1]
  • ≥ 4Å and < 5Å [14]
  • ≥ 5Å and < 6Å [17]
  • ≥ 6Å and < 8Å [20]
  • ≥ 8Å and < 12Å [8]

Model molecular weight

  • 100-250 kDa [1]
  • 500-1000 kDa [1]

Release Date

  • 2025 [6]
  • 2024 [41]
  • 2022 [13]

Author by name

  • Lyumkis D [60]
  • Dong X [54]
  • Sheng K [54]
  • Williamson JR [54]
  • Aiyer S [47]
  • Gebert LFR [23]
  • Macrae IJ [23]
  • Lee J [18]
  • Marquardt S [18]
  • Wiliamson JR [18]
  • Doerfel LK [13]
  • Popova AM [13]
  • Rabuck-gibbons JN [13]
  • Andrade L [6]
  • Biswas A [6]
  • Craigie R [6]
  • Dinh T [6]
  • Engelman AN [6]
  • Gray G [6]
  • Greenwood J [6]
  • Jang S [6]
  • Jing T [6]
  • Kvaratskhelia M [6]
  • Li M [6]
  • Li Z [6]
  • Passos D [6]
  • Shan Z [6]
  • Shin HJ [6]
  • Strutzenberg TS [6]
  • Zhang Y [6]
  • Zhang Z [6]
  • Zhou B [6]

Author by ORCID

  • Lyumkis D [60]
  • Williamson JR [36]
  • Aiyer S [24]
  • Gebert LFR [23]
  • Macrae IJ [23]
  • Sheng K [18]
  • Dong X [18]
  • Wiliamson JR [18]
  • Lee J [18]
  • Doerfel LK [13]
  • Andrade L [6]
  • Biswas A [6]
  • Dinh T [6]
  • Li M [6]
  • Engelman AN [6]
  • Passos D [6]
  • Jing T [6]
  • Kvaratskhelia M [6]
  • Shan Z [6]
  • Zhang Y [5]
  • Craigie R [1]
  • Zhou B [1]
  • Strutzenberg TS [1]

Journal

  • NUCLEIC ACIDS RES [36]
  • TO BE PUBLISHED [18]
  • BIORXIV [6]
  • NAT COMMUN [5]

Software

  • CRYOSPARC [60]

Microscope

  • FEI TITAN KRIOS [31]
  • FEI TALOS ARCTICA [25]
  • TFS KRIOS [4]

Electron Source

  • FIELD EMISSION GUN [60]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [46]
  • GATAN K3 BIOQUANTUM 6K X 4K [13]
  • FEI FALCON IV 4K X 4K [1]

External links

  • PDBe-Kb [3]
  • UniProt [3]
  • Gene Ontology [2]
  • InterPro [2]
  • PDB [2]
  • Pfam [2]
  • AlphaFold DB [1]
  • ChEBI [1]
  • DrugBank [1]
Sort by: Download
Showing 1 - 10 of 60. Page 1 of 6
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EMD-44962
Download Map
3D View
Tetrameric Complex of full-length HIV-1 integrase protein bound to the integrase binding domain of LEDGF/p75
Release date: June 25, 2025
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 9bw9
Q-score: 0.332

Jing T, Shan Z, Dinh T, Biswas A, Jang S, Greenwood J, Li M, Zhang Z, Gray G, Shin HJ, Zhou B, Passos D, Strutzenberg TS, Aiyer S, Andrade L, Zhang Y, Li Z, Craigie R, Engelman AN, Kvaratskhelia M, Lyumkis D

Nat Commun (2025) 16 pp. 9430-9430 [ DOI: doi:10.1038/s41467-025-64479-8 Pubmed: 41136407 ]

EMD-45103
Download Map
3D View
Consensus map of NL4-3 WT HIV-1 intasome
Release date: June 25, 2025
Resolution: 4.0 Å
EM Method: Single-particle

Jing T, Shan Z, Dinh T, Biswas A, Jang S, Greenwood J, Li M, Zhang Z, Gray G, Shin HJ, Zhou B, Passos D, Strutzenberg TS, Aiyer S, Andrade L, Zhang Y, Li Z, Craigie R, Engelman AN, Kvaratskhelia M, Lyumkis D

Nat Commun (2025) 16 pp. 9430-9430 [ DOI: doi:10.1038/s41467-025-64479-8 Pubmed: 41136407 ]

EMD-45104
Download Map
3D View
Top half of NL4-3 WT HIV-1 intasome
Release date: June 25, 2025
Resolution: 5.0 Å
EM Method: Single-particle

Jing T, Shan Z, Dinh T, Biswas A, Jang S, Greenwood J, Li M, Zhang Z, Gray G, Shin HJ, Zhou B, Passos D, Strutzenberg TS, Aiyer S, Andrade L, Zhang Y, Li Z, Craigie R, Engelman AN, Kvaratskhelia M, Lyumkis D

Nat Commun (2025) 16 pp. 9430-9430 [ DOI: doi:10.1038/s41467-025-64479-8 Pubmed: 41136407 ]

EMD-45150
Download Map
3D View
Bottom half of NL4-3 WT HIV-1 intasome
Release date: June 25, 2025
Resolution: 5.3 Å
EM Method: Single-particle

Jing T, Shan Z, Dinh T, Biswas A, Jang S, Greenwood J, Li M, Zhang Z, Gray G, Shin HJ, Zhou B, Passos D, Strutzenberg TS, Aiyer S, Andrade L, Zhang Y, Li Z, Craigie R, Engelman AN, Kvaratskhelia M, Lyumkis D

Nat Commun (2025) 16 pp. 9430-9430 [ DOI: doi:10.1038/s41467-025-64479-8 Pubmed: 41136407 ]

EMD-45151
Composite map
Download Map
3D View
Hexadecamer of NL4-3 WT HIV-1 intasome
Release date: June 25, 2025
Resolution: 8.0 Å
EM Method: Single-particle
Fitted PDBs: 9c29
Q-score: 0.219

Jing T, Shan Z, Dinh T, Biswas A, Jang S, Greenwood J, Li M, Zhang Z, Gray G, Shin HJ, Zhou B, Passos D, Strutzenberg TS, Aiyer S, Andrade L, Zhang Y, Li Z, Craigie R, Engelman AN, Kvaratskhelia M, Lyumkis D

Nat Commun (2025) 16 pp. 9430-9430 [ DOI: doi:10.1038/s41467-025-64479-8 Pubmed: 41136407 ]

EMD-70530
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3D View
Tetrameric full-length HIV-1 integrase protein complex
Release date: June 25, 2025
Resolution: 6.92 Å
EM Method: Single-particle

Jing T, Shan Z, Dinh T, Biswas A, Jang S, Greenwood J, Li M, Zhang Z, Gray G, Shin HJ, Zhou B, Passos D, Strutzenberg TS, Aiyer S, Andrade L, Zhang Y, Li Z, Craigie R, Engelman AN, Kvaratskhelia M, Lyumkis D

bioRxiv (2025) [ DOI: doi:10.1101/2024.01.26.577436 Pubmed: 38328132 ]

EMD-44564
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3D View
iSAT PNA - ctrl-C-b3
Release date: Nov. 13, 2024
Resolution: 6.0 Å
EM Method: Single-particle

Sheng K, Dong X, Aiyer S, Lee J, Marquardt S, Lyumkis D, Wiliamson JR

To Be Published

EMD-44565
Download Map
3D View
iSAT PNA - ctrl-E-a1
Release date: Nov. 13, 2024
Resolution: 4.3 Å
EM Method: Single-particle

Sheng K, Dong X, Aiyer S, Lee J, Marquardt S, Lyumkis D, Wiliamson JR

To Be Published

EMD-44566
Download Map
3D View
iSAT PNA - ctrl-E-a3
Release date: Nov. 13, 2024
Resolution: 5.1 Å
EM Method: Single-particle

Sheng K, Dong X, Aiyer S, Lee J, Marquardt S, Lyumkis D, Wiliamson JR

To Be Published

EMD-44567
Download Map
3D View
iSAT PNA - ctrl-E-a2
Release date: Nov. 13, 2024
Resolution: 6.1 Å
EM Method: Single-particle

Sheng K, Dong X, Aiyer S, Lee J, Marquardt S, Lyumkis D, Wiliamson JR

To Be Published

Sort by: Download
Showing 1 - 10 of 60. Page 1 of 6
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [60]

Current status

  • REL [60]

Sample type

  • Complex [60]
  • Protein [3]
  • DNA [1]
  • Ligand [1]

Organism

  • Escherichia coli [36]
  • Escherichia coli [18]
  • Human immunodeficiency virus 1 [6]
  • Human immunodeficiency virus 1 [3]
  • Homo sapiens [1]

EM Method

  • Single-particle [60]

Resolution

  • ≥ 3Å and < 4Å [1]
  • ≥ 4Å and < 5Å [14]
  • ≥ 5Å and < 6Å [17]
  • ≥ 6Å and < 8Å [20]
  • ≥ 8Å and < 12Å [8]

Model molecular weight

  • 100-250 kDa [1]
  • 500-1000 kDa [1]

Release Date

  • 2025 [6]
  • 2024 [41]
  • 2022 [13]

Author by name

  • Lyumkis D [60]
  • Dong X [54]
  • Sheng K [54]
  • Williamson JR [54]
  • Aiyer S [47]
  • Gebert LFR [23]
  • Macrae IJ [23]
  • Lee J [18]
  • Marquardt S [18]
  • Wiliamson JR [18]
  • Doerfel LK [13]
  • Popova AM [13]
  • Rabuck-gibbons JN [13]
  • Andrade L [6]
  • Biswas A [6]
  • Craigie R [6]
  • Dinh T [6]
  • Engelman AN [6]
  • Gray G [6]
  • Greenwood J [6]
  • Jang S [6]
  • Jing T [6]
  • Kvaratskhelia M [6]
  • Li M [6]
  • Li Z [6]
  • Passos D [6]
  • Shan Z [6]
  • Shin HJ [6]
  • Strutzenberg TS [6]
  • Zhang Y [6]
  • Zhang Z [6]
  • Zhou B [6]

Author by ORCID

  • Lyumkis D [60]
  • Williamson JR [36]
  • Aiyer S [24]
  • Gebert LFR [23]
  • Macrae IJ [23]
  • Sheng K [18]
  • Dong X [18]
  • Wiliamson JR [18]
  • Lee J [18]
  • Doerfel LK [13]
  • Andrade L [6]
  • Biswas A [6]
  • Dinh T [6]
  • Li M [6]
  • Engelman AN [6]
  • Passos D [6]
  • Jing T [6]
  • Kvaratskhelia M [6]
  • Shan Z [6]
  • Zhang Y [5]
  • Craigie R [1]
  • Zhou B [1]
  • Strutzenberg TS [1]

Journal

  • NUCLEIC ACIDS RES [36]
  • TO BE PUBLISHED [18]
  • BIORXIV [6]
  • NAT COMMUN [5]

Software

  • CRYOSPARC [60]

Microscope

  • FEI TITAN KRIOS [31]
  • FEI TALOS ARCTICA [25]
  • TFS KRIOS [4]

Electron Source

  • FIELD EMISSION GUN [60]

Film or detector model

  • GATAN K2 SUMMIT 4K X 4K [46]
  • GATAN K3 BIOQUANTUM 6K X 4K [13]
  • FEI FALCON IV 4K X 4K [1]

External links

  • PDBe-Kb [3]
  • UniProt [3]
  • Gene Ontology [2]
  • InterPro [2]
  • PDB [2]
  • Pfam [2]
  • AlphaFold DB [1]
  • ChEBI [1]
  • DrugBank [1]